[Retroperitoneal fibrosis: diagnosis and course].
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Biomedical subjects
Publications and source records attributed to B Dufour.
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In this article, the authors study the complications following all the kidney transplantations performed in their hospital between 1969 and 1980. During this period, 580 patients underwent 637 transplantations, including 120 (19%) with urological complications: urinary fistulae (49%), stenoses (28%), vesicorenal refluxes (13%), and calculi (10%). The postoperative mortality rate was 2.7%. Some patients presented with two or more complications. The circumstances of the discovery of the sequelae and the treatment prescribed are described in each case and a comparative study is made with other transplantation centers.
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Two random groups of sixty patients each were given an extract of pygeum africanum in one group, and a placebo in the other. The results highlight the placebo effect (50 per cent of cases), and that the extract provided an overall improvement in the functional symptoms. The differences between the two treatments were statistically significant for nocturnal frequency, difficulty in starting micturition, and incomplete emptying of the bladder.
The authors report a series of thirty seven patients presenting with vesicorenal reflux. The circumstances leading up to the discovery of the disorder, and the urographic and cystographic findings are described. of the 37 patients, 9 were treated medically, 6 by nephrectomy, and 22 by ureteral reimplantation, involving, in some of the cases, an extravesical dissection of the ureter.
The authors report a case of multiple thyroid metastases in a patient who had undergone excision of a renal adenocarcinoma eight years previously. At the first operation, there had been no sign of any metastases. A benign thyroid adenoma was also found.
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Congenital malformations and tumours of the bladder are the commonest indications of uretero-sigmoidostomy, an operation associated with the name of Coffey who perfected the technique. A part from the renal and metabolic complications of this operation, the risk of benign or malignant tumours at the anastamosis should not be overlooked. Four cases are reported which underline the incidence of juvenile polyps and mixed juvenile and adenomatous polyps which tend to degenerate. The medical literature is reviewed. Uretero-sigmoidostomy is a definite cause of tumour formation. The different pathogenic hypotheses are discussed. Colonoscopy is a method of detecting the tumour, of obtaining a histological diagnosis and treating benign polyps by diathermy under endoscopic control. This technique allows preservation of the anastomosis. The prevention of these lesions should be assured by annual endoscopy for 5 years after operation.
The authors describe a technique for the trans-vesico parietal exteriorisation of ureteric catheters inserted endoscopically. Once the ureteric catheters have been inserted, the free end is pushed into the bladder. A suprapubic trocar opens the way to the outside by a trans-vesico parietal route. A foreign body forceps is inserted endoscopically and grasps the ureteric catheter, inserting its end into the trocar. The catheter can then be pushed through to the outside without the need to "open" the bladder.
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Twenty-five cases of invasive carcinoma of the bladder treated by surgery, radiotherapy and chemotherapy are discussed. Cis-diammine dichloroplatinum (CDDP) was used in 8 cases, bleomycin in perfusion in 6 cases and a combination of CDDP and adriamycin in 11 cases. Of 8 cases with lymph node invasion, 4 are alive 5 to 21 months after the start of treatment. Of 12 who were followed up and has no nodal involvement, 9 are alive 5 to 52 months from the start of treatment. The tolerance to treatment is poor, but the results are encouraging. Therefore, we suggest a program of treatment consisting of intense preoperative radiotherapy, partial or radical cystectomy, followed by an combination of 100 mg of CDDP and 60 mg of adriamycin monthly for 9 months.
An anterior subcostal transperitoneal approach was employed in a series of 50 operations, including 43 enlarged nephrectomies for cancer. The advantages of this technique are that it gives direct access to the aortic diaphragmatic orifice and the large vessels and upper pole of the kidney, it is simple to enlarge, and it is solid. It has only minor inconveniences. As only the abdominal cavity is opened, the patient's respiratory function is preserved, especially in the elderly and those with respiratory insufficiency. With a lower mortality and morbidity, a shorter period of hospitalisation, and lower costs, it enables the same enlarged excision to be performed as during thoraco-phrenolaparotomy. It can also be employed for other types of operation on the kidneys and renal vessels, the adrenals, or the lateral aortic glands.
Fifty-three surgical operations, including 43 enlarged nephrectomies for cancer, were conducted employing the anterior transperitoneal approach along the costal margin. This technique has been used for the last 4 years for excision of renal cancers, as well as certain difficult nephrectomies (pyonephrosis, repeated kidney operations), and for surgery on the renal vessels, the adrenals, and the peri-aortic lymphatics. The approach is solid and easy to enlarge, and gives direct access to the diaphragm, the large vessels, the renal pedicle, and the upper pole of the kidney. As only the abdomen is incised, morbidity is low.
When the renal pelvis and the proximal ureter are destroyed, surgical repair is always difficult. In case of a loss of substance of the upper ureter, it is possible to replace the obstructed (or destroyed) segment and to preserve the healthy iliopelvic ureter. The 'renoureteric bypass' consists of the insertion of an intermediate segment between the lower calyx of the kidney and the lumboiliac ureter. A prosthesis or an intestinal loop may be used to restore the continuity of the urinary tract. The results obtained in dogs being excellent, the technique was applied successfully in man in 2 cases.
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