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Biomedical subjects

B Delcambre

Publications and source records attributed to B Delcambre.

At least 163 records · Page 9Linked to original sources
PubMed1978

[Circulating immune complexes and anti-IgG antibodies in rheumatoid arthritis].

Anti-IgG antibodies were studied in 222 patients hospitalized in a Rheumatology service using "radio-immuno-precipitation-PEG-assay" (RIPEGA), The presence of anti-IgG antibodies was observed in 94 per cent of sero-positive rheumatoid arthritis (RA+), 88 percent of seronegative rheumatoid arthritis (RA--), 50 percent miscellaneous chronic inflammatory rheumatisms (CIR) and 77 percent of no-classifiable chronic inflammatory rheumatisms. The study of circulating immune complexes (CIC) using the CIC-125 I linkage tests, carried out on 101 RA cases, demonstrated their presence in 80 per cent of RA+ and 85 per cent of RA--. The comparison of these two factors during RA showed a concordant relationship that was statistically significant. The presence of the rheumatoid factor (RF) in the form of complexes in the blood stream, is discussed.

Antibodies, Anti-Idiotypic↗
PubMed1977

[Value of the detection and characterization of circulating immune complexes in rheumatoid arthritis].

The authors analyse the value of research into and identification of immune complexes (IC) in chronic inflammatory rheumatisms (CIR) and in rheumatoid polyarthritis (RP) in 93 patients hospitalise in a Rheumatology Department. Comparative levels of ICs were established simple and quick technique of measuring the 50% haemolytic complement (HC 50) used up by the ICs. The rheumatoid factor (RF) is identified at the PEG IC precipitates with the Waaler-Rose test. The existence of raised levels of IC containing RF in both seropositive and seronegative PRs and to a similar degree in a non-negligable percentage of clinically non-classable RICs conforms the diagnostic value of this research. On the other hand there is no relationship between the levels of ICs and either clinical signs or age of the illness. In RPs other than CIR circulating ICs are found whose nature is still unknown.

Antigen-Antibody Complex↗
PubMed1977

The use of the radioimmunoprecipitation-PEG assay (RIPEGA) to detect anti-IgG antibodies.

A new procedure, the radioimmunoprecipitation--P.E.G. assay (RIPEGA) is proposed for the detection of anti-IgG antibodies (anti-IgG Ab). This sensitive and reproducible test was performed by incubation of radio-labelled human IgG (125I-IgG) with patient's sera. Separation of free from complexed 125I-IgG was achieved by a 7% P.E.G. precipitation. Preliminary results demonstrated anti-IgG Ab in 84.4% of the cases of sero-positive rheumatoid arthritis (R.A.), 85% of seronegative R.A., 43% of other forms of inflammatory arthritis, 50% of unclassified arthritis and in 10.5% of the control subjects.

Arthritis, Rheumatoid↗