Search PubMed⌕ Search

Biomedical subjects

B Daicker

Publications and source records attributed to B Daicker.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Perilenticular tissue changes in intraocular lenses worn without complications].

Eighteen eyes containing an intraocular lens (IOL) removed post mortem from 16 patients after an uncomplicated postoperative course of up to 50 months, and 2 IOLs removed intraoperatively were studied macroscopically, histologically and ultrastructurally to detect changes in the lenses themselves and in the surrounding ocular tissues. Various types of lens-loop degradation, erosion of the iris pigment epithelium with formation of posterior synechiae and pressure atrophy of the iris stroma were found, but there was little evidence of iritis. A mixed cell population containing many foreign-body giant cells had settled on most lenses, some of which were encased in membranes. The loops of one Sinskey PCL had penetrated the ciliary body and iris root to reach the trabecular meshwork. The significance of these findings is discussed.

Cataract Extraction↗
PubMed1984

Septo-optic pituitary dysplasia. Observations on three patients.

Septo-optic pituitary dysplasia is a relatively rare but pathophysiologically interesting malformation of the brain midline structures including optic chiasm and nerves, hypothalamus, neurohypophysis and septum pellucidum. The lesion develops between the 5th and 8th week of pregnancy. The cause is unknown but heredity seems unlikely. Symptoms result from hypothalamic and neurohypophyseal insufficiency of variable severity combined with reduced vision due to hypoplasia of optic nerves and chiasm. Prognosis is variable, depending on the severity of the defect as well as on the earliest time of diagnosis followed by suitable hormone substitution and specialized care of blindness. We present the clinical course in three patients and the pathological findings in one patient who died in the 14th month of life.

Child↗
PubMed1983

[Heterotopic smooth muscle in the choroid].

A histological and ultrastructural description of a case with an area of smooth muscle in the choroid of both eyes in presented. This was a chance finding in the globes of a deceased female patient whose lids (OU) as well as the conjunctiva and sclera of one side were affected by mycosis fungoides. The heterotopic smooth muscle in the choroid is interpreted as being an isolated malformation in otherwise nondysplastic eyes. It is possible that the rare leiomyomas of the choroid occur in such heterotopias, which have not been observed before.

Adult↗
PubMed1982

[Inner retinal traction breaks resembling a sharkmouth in areas of peripheral cystoid degeneration (author's transl)].

10 predominantly diabetic eyes from a mixed collection of 1,561 enucleated specimens showed extended, linear, ridgelike elevations of the inner retinal layers within areas of cystoid degeneration. These ridges lie peripherally and run parallel to the ora. The posterior slope of each ridge contains a chain of inner retinal holes which extend into the cavities of the cystoid degeneration. The changes, viewed from behind, resemble an open sharkmouth. The posterior border of the vitreous base adheres to the crest of the ridge behind which the vitreous itself is detached. The ridges and inner holes are thought to result from vitreous traction, chronic rather than acute, acting on peripheral areas of cystoid degeneration which can presumably be elevated more easily than normal retina.

Adult↗
PubMed1982

Anterior bulbus perforation and vitrectomy in the 'minipig'.

Wound healing after experimental anterior eye perforation, including lens, ciliary, body and vitreous, was studied in 12 miniature pigs (minipigs). In half of the eyes, perforation was followed by removal of the damaged lens and suturing of the wound. In the other half, a primary subtotal vitrectomy was performed after removal of the lens. The behaviour of the connective tissue in the wound-healing process was not fundamentally changed by subtotal vitrectomy. In both groups very little fibrous ingrowth into he vitreous structure was observed, suggesting that the pig vitreous has marked antifibroplastic properties. The anatomical and technical features of vitrectomy in the minipig, and the advantages and disadvantages of this animal model are discussed. It appears that the eye of the minipig is ideal for the study of biochemical factors preventing fibrous ingrowth into the vitreous.

Animals↗
PubMed1982

[Cogan-Reese syndrome].

The clinical, histological and ultrastructural findings in a case of Cogan-Reese syndrome (iris nevus) are presented. The typical iris nodules first appeared 14 years after a unilateral, juvenile, open-angle glaucoma was diagnosed. No lasting regulation of the intermittently elevated pressure was possible either medically or surgically. The failure of two filtering operations was due to the histologically verified endothelialization of the blebs. Endothelialization and deposition of Descemet's membrane on the anterior surface of the lens and on the zonule is described for the first time in this syndrome. The histological findings support the view that the peripheral anterior synechiae and iris nodules are secondary to the endothelialization. Hence the diagnosis of Cogan-Reese syndrome cannot be made until relatively late in the course of this disease. Cytological similarities between the proliferating endothelium in this case and in Chandler syndrome support the recent hypothesis that the Cogan-Reese syndrome belongs to the irido-corneal-endothelial group of syndromes.

Adult↗
PubMed1981

[Metastatic tumors of the uvea (author's transl)].

Uveal metastases are now the most common intraocular tumors. The ophthalmologist is becoming increasingly involved in their diagnosis and treatment due to advances in systemic cancer therapy. These metastases can often be distinguished from autochthonous tumors by reason of their location, appearance and behavior. A synopsis of these characteristics is exemplified by a short review of the literature and by original histological and clinical material from patients with uveal metastases arising from a wide range of primary tumors. The lessons which may be derived from this material for the diagnosis and local treatment of these metastases is discussed.

Breast Neoplasms↗
PubMed1980

[Corona serrata at the root of the iris].

In certain blue-eyed patients with shallow anterior chambers an irregular whitish saw-tooth pattern is visible at the root of the iris, especially on the temporal side. This finding does not appear to have been described previously. The anatomical reasons for this iris root pattern are discussed.

Eye Color↗
PubMed1980

[Medullary thyroid carcinoma metastasizing to the choroid, ciliary body and iris: clinical and pathological findings in two cases (author's transl)].

Two cases (four eyes) of medullary thyroid carcinoma with metastases in the choroid, ciliary body and iris are described for the first time. In one eye the choroidal metastases were destroyed clinically by photo- and cryocoagulation. In another eye coagulation of a tumor may have facilitated transscleral extension into the orbit. The clinical conclusions arising from the pecularities of these tumors are discussed. It is particularly striking that in 2 patients with this rare tumor metastases developed in the anterior uvea in all four eyes.

Carcinoma↗
PubMed1979

[Studies on pigmented surface wrinkling retinopathy by scanning electron microscopy (author's transl)].

The light- and scanning electron microscopic appearance of 3 areas of pigmented epiretinal fibroplasia (pucker) are described in an eye removed following detachment surgery. The centre of each area of pucker consists of a fibroglial sheet covered by retinal pigment epithelium. The surface morphology of these cells resembles typical or slightly degenerated epithelium. Extensive areas of these pigment epithelial sheets were pigmentfree. There was no evidence that the pigment epithelial sheets exerted either direct or indirect traction on the inner surface of the retina. The origin of these cells and their role in the formation of retinal wrinkling is discussed.

Aged↗
PubMed1979

[The histological substrate of the extraocular muscle thickening seen in dysthyroid orbitopathy (author's transl)].

The diagnosis of dysthyroid orbitopathy can be confirmed in over 80% of cases by demonstrating thickened extraocular muscles on computertomograms. The criteria are briefly discussed and the histological picture of the muscle thickening is described. The changes are variable and depend upon the course of the disease. Fatty infiltration is the most important factor causing muscle thickening, mucopolysaccharide deposition and fibrosis contribute less to the increased muscle volume, while inflammatory cell infiltration and proliferation of the endomysium play a minor role. The fatty infiltration and fibrosis, representing late changes, are probably therapy resistant in contrast to the other changes.

Adipose Tissue↗
PubMed1979

[Leiomyoma of the ciliary body - misdiagnosis leading to an unconventional but successful surgical approach].

Report on a leiomyoma of the ciliary body in a 12-year-old girl. The clinical findings were misinterpreted as a traumatic ciliary body cyst because of the associated iridodialysis, the fact that the tumor could be transilluminated, because it appeared cystic on ultrasonography, and because there was a history of severe cranial trauma. In the course of an attempt to puncture the presumed cyst a cherry-sized ciliary body tumor was revealed. It proved possible to shell this out without performing an iridocyclectomy. An elective enucleation would have been performed had the true diagnosis been known preoperatively. Due to the misdiagnosis and the resulting unconventional approach the eye was preserved with some residual functions. the histological picture was that of a leiomyoma, a tumor rarely found in the ciliary body. The histological and electronmicroscopic appearance are described and compared with the few cases previously reported.

Adolescent↗
PubMed1978

[Studies on fibrous and fibro-glial surface wrinkling retinopathy by scanning electron microscopy (author's transl)].

The scanning electron microscope was used to examine 16 cases of epiretinal membrane formation and retinal puckers which occurred in a variety of primary retinal disorders. In this first section the authors describe three types of epiretinal membranes: (1) Fibrous acellular membranes with and without vitreous adhesions. Retinal puckering was caused by vitreous traction with collagen strands binding the residual folds. (2) Fibrous membranes containing isolated glial cells. (3) Fibrous membranes partly covered by sheets of glial cells. In all three forms the acellular fibrous component is believed to represent vitreous cortex remnants. The invariable presence of these fibrous membranes at sites of retinal pucker and their relationship to wrinkled internal limiting membrane suggests that contraction of these membranes is responsible for retinal puckering. Morphological evidence of glial membrane contraction and collagen production by glial cells was not found.

Connective Tissue↗
PubMed1978

[The macular fatty degeneration of the peripheral retina a variety of the snail track degeneration (author's transl)].

A previously undescribed form of snail-track degeneration with scattered flecks was found in three eyes with absolute glaucoma. Light- and electron-microscopic examination of these lesions in the retinal periphery revealed atrophy and gliosis with massive accumulation of fat within the astrocytes and Müller's cells. It was not possible to explain the patchy distribution of the lesions. The fatty change in the macroglia is believed to indicate 'in situ breakdown' of slowly atrophying retina. Morphologic and pathogenetic similarities suggest that all forms of snail-track degeneration with snowflakes represent nonspecific fatty degeneration of the retina.

Adult↗
PubMed1978

[Ocular findings in reno-facial dysplasia (Potter-syndrome) (author's transl)].

The clinical and pathological details of a case of reno-facial dysplasia are presented and described. Hyperplasia and lamination of Bowman's membrane, corneal endothelial dystrophy with degenerative changes in the posterior stroma, hypoplasia of the retinal ganglion cell and nerve fibre layers, and severe changes in the retinal and iris blood vessels are believed to be pathognomonic ocular features of this syndrome, in addition to cataract and signs of immaturity. These findings are compared with the few descriptions of the syndrome previously published. The corneal damage is postulated to result indirectly from oligohydramnios which causes chronic compression of the globes and thus endothelial damage due to contact with the spherical cataracts. The pathological changes in the retinal and iris vessels are either genetically determined or the result of chronic hypoxia.

Abnormalities, Multiple↗
PubMed1978

[Spotty fatty retinal degeneration (author's transl)].

The author describes the macroscopical, microscopical and ultrastructural features of a peculiar form of snail track degeneration, which was found in 3 eyes with absolute glaucoma. The snowflakes are concentrated to scattered patches in an extensive frosted area of the peripheral retina. The glittering points consist of neutral fat in a gliotic and atrophic retina. Electron microscopy examination shows fat droplets within the astrocytes and Müller cells. These findings are believed to be the expression of a "in situ break down" of a very slowly atrophying retina by the macroglia.

Adult↗