Biomedical subjects
B D Radotra
Publications and source records attributed to B D Radotra.
Meningeal melanocytoma: report of two cases.
Two cases meningeal melanocytoma, one each at cranial and spinal location, are described. Neurological deficits in both cases improved following surgery. Pathological features of this rare tumour are discussed.
Synovial sarcoma of the nasopharynx.
A case of primary synovial sarcoma of the nasopharynx in a 28-year-old man is presented. The patient was treated with operation followed by radiotherapy and is free of recurrence or evidence of metastasis 40 months after treatment. Because of the extreme rarity of this tumor in this site, the importance of its recognition is stressed.
Entomophthoromycosis: clinico--mycological study of a case.
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Reticulate acropigmentation of Kitamura.
Reticulate acropigmentation of Kitamura in a mother and her daughter is reported. Both demonstrated peri-orbital involvement in addition to involvement of acral areas, face and eyelids which has not been recorded before.
Penile venous haemangioma.
A case of venous haemangioma at the base of penis is reported. The patient presented with complaints of pain, hemilateral tilting during erection and progressively increasing swelling at the base of penis. The lesion was resected surgically and was diagnosed on histopathological examination to be penile venous haemangioma. Possible aetiopathogenesis of haemangioma in general and characteristics of venous haemangioma in particular are briefly discussed. A similar case report has not been found in the literature.
Rothmund-Thomson syndrome in two siblings.
Rothmund-Thomson syndrome, a rare autosomal recessive disorder, is characterized by photosensitivity; specific skin changes including poikiloderma, atrophy, and telangiectases; juvenile cataracts; short stature; and bone defects. We describe two siblings with this syndrome.
Condylomata lata of the eyelids.
A patient with secondary syphilis and extensive condylomata lata on the face, neck, axillae, groins, and genitalia is described. His facial condylomata lata affected the eyelids, medial canthus, nasolabial folds, angles of the mouth, and chin. Condylomata lata of the eyelids has not been described previously.
Primary renal Hodgkin's lymphoma: case report.
Primary extranodal Hodgkin's lymphoma is very rare. The first case of primary renal Hodgkin's lymphoma is reported.
Mutilating keratoderma--a case report.
A 19 year old girl had mutilating palmoplantar keratoderma with generalised ichthyosiform dermatosis and linear verrucous plaques in popliteal fossae. Her mother had similar disorder.
Eosinophilic granuloma with cord compression.
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Lupus vulgaris following BCG vaccination.
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Positive Nikolsky's and bulla-spread signs in acute bullous lichen planus.
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Lupus nephritis with polycystic kidney disease.
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Pathology teach and tell: neonatal hemochromatosis with massive hepatic necrosis.
Neonatal hemochromatosis (NH) is an uncommon disorder clinicopathologically defined by severe liver disease of intrauterine onset associated with extrahepatic siderosis that spares reticuloendothelial elements. NH phenotypically is a similar disorder to hereditary hemochromatosis. However, its extremely early onset of liver failure makes it notably unique. Massive liver necrosis in the newborn is a rare occurrence, but whenever present hemochromatosis should be considered in the differential diagnosis. Herein, we report a case of neonatal hemochromatosis that had massive hepatic necrosis with sparing only little parenchyma. The outcome was fatal within the first month of life.
Spectrum of pediatric developmental and genetic renal lesions and associated congenital malformations--an autopsy study from north India.
Pediatric developmental and genetic renal lesions are a known cause of mortality in the perinatal/neonatal period. These lesions are associated with a wide range of extrarenal congenital malformations that influence the outcome of the patients. In this autopsy study, we have analyzed the spectrum of pediatric developmental and genetic renal lesions and their associated congenital malformations. A total of 4,099 autopsies (20 weeks of gestation to 1 year of life) were reviewed, of which 158 cases (3.85%) of pediatric developmental (143 cases) and genetic renal lesions (15 cases) were found. Autosomal recessive polycystic kidney disease was the commonest genetic lesion. Primitive ducts with cuffing of immature mesenchyme--the sine qua non of renal dysplasia--was found in all cases of dysplasia. Associated congenital malformations were seen in all cases and thus a thorough search for them is mandatory. Ductal plate malformation was found in all cases of autosomal recessive polycystic kidney disease and in 1 case of bilateral multicystic dysplasia.
Histomorphology of renal dysplasia--an autopsy study.
A retrospective analysis of pediatric autopsies in the past 18 years was done with the aim of studying the histomorphology of renal dysplasia. Renal dysplasia comprised 150 (3.66%) of the 4,099 pediatric autopsies from 20 weeks of gestation to 1 year of life. Primitive ducts with the fibromuscular collar, the sine qua non of renal dysplasia, was seen in all cases. Lobar disorganization and cysts were seen in all cases except for the 7 cases of hypodysplasia. Other elements were seen in varying proportions: cartilage in 33.7%, bone in 1.08%, thickening of basement membrane of the primitive ducts in 64.13%, extramedullary hematopoiesis in 98.9%, nerve twigs in 72.8%, and nodular renal blastema in 2.17% cases. In unilateral multicystic dysplasia/renal agenesis, the contralateral kidney showed abnormalities in 44.45% and 47.37% of cases, respectively.