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Biomedical subjects

B Chiche

Publications and source records attributed to B Chiche.

At least 37 records · Page 2Linked to original sources

[A study of pancreatic insulinomas by electron microscopy. 9 cases (author's transl)].

Nine hypoglycaemia-inducing pancreatic tumours were studied by electron microscopy. In 8 of these tumours, it was possible to identify, within the cell cytoplasm, secretory granules with a "paracrystalline" content, identical in appearance to the granules of the B cell of the normal human pancreas. Thus electron microscopy would appear to be a reliable and sensitive method for the morphological identification of these endocrine tumours of the pancreas.

Adenoma, Islet Cell↗

[Necrosis in acute pancreatitis. Surgical and anatomopathological comparisons. 7 cases].

The surgeon should take pains to section and study himself the operative specimen after excision for acute pancreatitis, in order to understand the true nature of the lesions, which the most attentive and competent pathological examination cannot describe as vividly as direct examination by the operator. Often he will be surprised to find that the lesions, predominant in the capsule, are less profound and less severe than he had thought at first sight. Findings of this sort, if they were to be confirmed, would put into doubt the principle itself of routine pancreatectomy for acute pancreatitis.

Acute Disease↗

[Jejuno-ileal short-circuit operations in the treatment of obesity. 16 personal cases (author's transl)].

The authors report a personal experience of 16 cases and in the light of data in the world literature, the authors discuss the controversial method of treatment of very severe obesity when medical treatment has failed. The onset of various complications linked mainly to intestinal malabsorption, should make one careful in the indications for surgery which may, however, be applicable in certain cases.

Adult↗

[Perforation of gastroduodenal ulcers. Therapeutic trends. Apropos of 284 cases].

The authors analyse retrospectively 284 case records of perforation of gastric and duodenal ulcers treated between 1961 and 1972 and, from a study of the literature, the authors attempt to draw up prognostic factors which permit one to apply to this complication of ulcer disease, the most efficient short and long-term treatment.

Adolescent↗

[Sarcomas of the gallbladder].

The authors report two recent personal cases including one explored by retrograde cholangiography and discuss the main clinical, pathological characteristics of this rare disease. They emphasize the severity of the course which does not usually last more than a few weeks after the onset of the first signs.

Aged↗

[Ligation of the hepatic artery for metastases from a carcinoid tumor].

Following ligature of the hepatic artery in the treatment of hepatic metastases of a carcinoid tumour of the small bowel, the authors noted a spectacular regression in functional symptoms. Several similar cases are recorded in the literature and similar findings given. The comfort, even though short-lived, which ligation brings justifies its use.

Carcinoid Tumor↗

["Pearl-string artery" with mesenteric localization].

Angiorgrams sometimes show regular and symetrical corrugations of the arterial outline. The shadows have been given various names: pearl string arter, bamboo pattern and so on. Involved arteries are mostly those of the extremities, especially the lower limbs. The authors have found a case involving the mesenteric artery. Usually, there is no pathological state of the arterial wall. Thus, surgical action is unnecessary.

Adult↗

[Surgical methods in non-traumatic perforations of the colon into the free peritoneum (36 cases)].

When operating as an emergency for a perforation of the colon should one carry out a by-pass operation, colostomy or restore intestinal continuity? 36 colonic perforations are reported here, as a complication of cancer in 50 p. 100 of cases, or sigmoiditis in 38 p. 100 of cases. The perforation was situated on the sigmoid in 77 p. 100 of cases. 13 by-pass operations were carried out with a 23 p. 100 mortality, 12 colectomies without anastomosis with a 50 p. 100 mortality, and 2 colectomies with restoration of continuity, 9 p. 100 mortality. The overall mortality was 27.7 p. 100 much less than reported by other authors but, nevertheless partly due to the severity of peritonitis due to the presence of feces and, partly due to the operation adopted. The present attitude of the authors depends on the merits of each case. A large incision is made and the peritoneum thoroughly cleaned. If the surgeon is experienced, colonic resection is advisable for perforated cnacer and certain cases of sigmoiditis. Restoration of continuity depends, above all, on the anatomical condition of the colon above the lesion. Hartmann's resections or by-pass operations thus still have indications.

Adult↗