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Biomedical subjects

B Braun

Publications and source records attributed to B Braun.

At least 163 records · Page 9Linked to original sources
PubMed1981

Ultrasonically guided fine needle aspiration biopsy of hepatic and pancreatic space-occupying lesions and percutaneous abscess drainage.

Ultrasonically guided fine needle aspiration biopsy as a safe, easy and uncomplicated procedure permitted cytological diagnosis in 54 out of 57 patients (94.7%) with confirmed tumor infiltrations of the liver and in 25 out of 30 patients (83.3%) with sonographically localized space -- occupying tumor-suspect lesions of the pancreas, 22 of which were verified as pancreatic cancer by laparatomy or autopsy, 3 patients suffered from malignant lymphoma. False negative results were obtained in 1.8% and 6.7%, respectively. There was no false positive diagnosis of neoplasm. Ultrasonically guided aspiration biopsy thus appears to be an excellent method for verification of clinically or sonographically suspected hepatic or pancreatic tumors or such suspected by other procedures. 42 cysts or abscesses in pancreas and liver were punctured and drained in 8 cases, using a flexible catheter. The therapeutical management of cysts or abscesses under ultrasonic guidance may shorten hospitalization or avoid intraabdominal operation.

Biopsy, Needle↗
PubMed1981

[Diagnosis of focal nodular hyperplasia of the liver (author's transl)].

In two female patients with hypothalamic-hypophyseal Cushing's syndrome who had not taken oral contraceptives, upper abdominal sonography showed three liver tumours as chance findings. In one case the left lobe was involved alone and in one case both lobes. None of the three tumours could be demonstrated by means of computer assisted tomography. Autopsy in one case and liver arteriography and scan in other other led to the diagnosis of focal nodular hyperplasia of the liver. These cases demonstrate the importance of sonography in the recognition of liver tumours. A connection between the overpopulation of adrenocorticosteroids and the formation or enlargement of focal nodular hyperplasia of the liver cannot be excluded.

Adult↗
PubMed1981

[Percutaneous transhepatic gallstone extraction (author's transl)].

Gall stones 1-3 cm in size were removed in three out of four patients from the common bile duct using a Dormia basket via the percutaneous transhepatic route. This method is indicated in selected cases: inoperable patients or those with a high surgical risk, and calculous obstruction after hepatico-jejunostomy. The method is limited in stones over 1 cm by their hardness.

Aged↗
PubMed1981

[Ultrasound and guided aspiration puncture in delayed bleeding of splenic rupture (author's transl)].

We report on ultrasonic findings on 6 patients who suffered from subcapsular or delayed traumatic bleeding of the spleen. All patients had been hospitalized in our department of internal medicine because of a misinterpretation of their clinical symptoms. In 4 patients we secured the intraperitoneal bleeding with ultrasonically guided fine needle aspiration puncture. In case of a suspected ruptured spleen we suggest ultrasonic tomography with guided aspiration puncture at the beginning of diagnostic measures before invasive procedures (peritoneal lavage, angiography) and during follow-up.

Adult↗
PubMed1981

The significance of serologic, histologic, and immunohistologic findings in the prognosis of 88 asymptomatic carriers of hepatitis B surface antigen.

Eighty-eight asymptomatic carriers of hepatitis B surface antigen (HBsAg) were followed with biochemical, serologic, histologic, and immunohistologic studies over a period of four years. None of the 78 HBsAg carriers with normal or minimally changed liver tissue, antibody to hepatitis B e antigen (HBeAg) in serum, and no intranuclear hepatitis B core antigen (HBcAg) developed a chronic inflammatory liver disease. Four individuals lost circulatory HBsAg, and at least two individuals terminated their HBsAg carrier state. Seven asymptomatic HBsAg carriers with chronic hepatitis were characterized by HBeAg in serum and intranuclear HBcAg. However, three HBsAg carriers with chronic hepatitis and an absence of intrahepatocellular HBcAg were positive for antibody to HBeAg over the observation period. The mechanism that leads to chronic hepatitis in these patients remains to be determined.

Adult↗
PubMed1981

Ultrasonic demonstration of renal vein thrombosis.

The sonographic findings of renal vein thrombosis are described in a patient examined for pain in the upper right abdomen. Since sonographic findings of the kidney itself are nonspecific, as are clinical appearance, laboratory data, and excretory urography, direct sonographic visualization of thrombus within the lumen of the renal vein and the inferior vena cava is of major importance in the diagnosis of renal vein thrombosis.

Humans↗
PubMed1980

[Captopril in the treatment of essential hypertension (author's transl)].

The antihypertensive effect of captopril was tested on 19 patients with essential hypertension, WHO grade I or II. In 11 patients blood pressure levels returned to normal over an observation period of 12 weeks at a dose of 3 C 50-150 mg daily (group A). In eight patients with grade II hypertension the absolute blood-pressure reduction was the same, but did not reach normal levels (group B). Although additional intake of propranolol, at a dose of 3 X 40 mg daily, achieved further reduction, normal pressures were still not attained. Initial blood pressure levels were higher and plasma-renin activity lower in patients of group B than of group A. There was a definite rise in plasma-renin activity with captopril, but corresponding to the suppression of plasma-renin in severe hypertension it was less. There was a fall in plasma-aldosterone levels, corresponding to a reduced angiotensin II level as a result of inhibition of the converting enzyme. The fall in plasma-aldosterone activity was less in severe hypertension, although there was the same inhibition of converting enzyme activity in both groups. Normochromic anaemia was noted in three patients, requiring further observation and explanation. No patient developed orthostatic hypotension or reflex tachycardia.

Adult↗
PubMed1979

[Modern methods in localization of pheochromocytomas (author's transl)].

In six patients with adrenal pheochromocytoma the tumors were localized by ultrasonography, phlebography of the adrenal glands and by estimation of plasma catecholamines selectively obtained from the vena cava and the adrenal gland veins. All tumors were localized by selective catecholamine estimation, five by ultrasonography, and four by phlebography. The smallest pheochromocytoma of 1.5 g weight was only localized by selective catecholamine estimation but not by ultrasonography or phlebography. This tumor, however, had been visualized by computed tomography. To avoid diagnostic errors by selective catecholamine estimation, it is important to withdraw blood from the adrenal gland veins prior to the injection of any radiographic contrast media, since this may result in an extremely enhanced secretion of catecholamines from the adrenal medulla.

Adrenal Gland Neoplasms↗
PubMed1979

Real-time ultrasound examination in the diagnosis of gastrointestinal tumors.

Inflammatory and neoplastic infiltrations of the intestinal wall lead in advanced stages to a tumorous thickening that can be visualized by ultrasound as the so-called cockade sign. The possibilities and limitations of ultrasound diagnosis of gastrointestinal tumors are presented. Over a period of 2 years, 73 tumors were diagnosed, 39 primarily by means of ultrasound with the real-time technique; 15 tumors were curatively resected at the time of primary ultrasound diagnosis.

False Positive Reactions↗
PubMed1979

[Grey-scale ultrasound in the diagnosis of cystic lesions of the kidney (comparison with excretory urography) (author's transl)].

In a total of 155 cystic renal lesions diagnozed by means of ultrasound the correct differentiation of cystic or solid consistency could be determined in 96.8% of cases. The sonographic result was inaccurate or false in only 2.6%. Sonography also determined the correct morphological and anatomical type of the liquid space-occupying formation in 89%. Pathological cavities of the renal pelvis as well as hydronephroses were the cause of incorrect diagnoses. 36.6% of solitary renal cysts revealed by ultrasound (average diameter of cyst: 3.9 cm), could not be detected by pyelography; radiology most frequently failed to determine cortical renal cysts. Sensitivity and specificity of nephrosonography for detection of cystic malformation of the kidney were distinctly better than pyelography. Out of a total of 34 patients with hereditary polycystic renal disease (HRPD) sonography diagnozed multiple cysts of the liver in 15 cases (44%). The use of ultrasound in examining relatives of patients with HPRD enables an earlier diagnosis of the chronic progressive disease.

Aged↗