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Biomedical subjects

B Azadeh

Publications and source records attributed to B Azadeh.

At least 37 records · Page 2Linked to original sources
PubMed1989

Verruciform xanthoma of the penis.

Verruciform xanthoma is a rare pathologic entity with a predilection for the oral mucosa. A case of verruciform xanthoma involving the penis, the second reported in this location, is presented.

Adult↗
PubMed1987

Sedaghatian congenital lethal metaphyseal chondrodysplasia--observations in a second Iranian family and histopathological studies.

In 1980, Sedaghatian described in two brothers and one sister a neonatally lethal disorder associated with slight rhizomelic limb shortness, mild platyspondyly, and severe metaphyseal dysplasia. Here data are presented on another Iranian infant with the Sedaghatian syndrome who died on day 4 and was found to have histologic evidence of severe epimetaphyseal dysplasia. The occurrence in children of both sexes in one instance, born to normal parents who were first cousins, and currently apparent confinement of the disorder to Iranians suggests that the Sedaghatian syndrome is an autosomal recessive trait with high gene frequency in Iranians. This may be a more complexly pleiotropic syndrome than suggested by the roentgenograms, since one of Sedaghatian's patients also had "microphthalmia, asymmetry of ears, depressed nasal bridge, broad nose, short neck, prominent sternum, and short lower extremities."

Bone and Bones↗
PubMed1985

Histological spectrum of cutaneous leishmaniasis due to Leishmania tropica.

Skin biopsies from 117 cases of acute and 23 cases of lupoid leishmaniasis were studied. Of the 117 acute cases, anergic macrophage response were seen in 44, diffuse necrosis in 9 and focalized necrosis in 11 biopsies; the remaining 53 biopsies showed scanty or no parasites with a few to abundant epithelioid cells probably representing post necrotic changes before complete healing of the lesions. The 23 biopsies of lupoid leishmaniasis showed rather well organized epithelioid granulomata surrounded by lymphocytes, inconspicuous plasma cells, no amastigotes and no necrosis. Lupoid cases showed strong delayed hypersensitivity with leishmanin and low serum antibody titres. It appears that the lesions of urban cutaneous leishmaniasis spend a long time in the anergic phase. Partial destruction of parasites by activated macrophages together with gradual elevation of antibody levels prepares the appropriate antigen-antibody ratio for optimum development of necrosis at PI3 leading to effective elimination of parasites. Plasma cells appear to be important in the induction of necrosis and inhibition of epithelioid granulomata. A significant inverse relationship has been found between plasma cells and epitheloid cells. The delayed hypersensitivity observed in lupoid leishmaniasis is probably the result of a poor humoral response evidenced by inconspicuous plasma cells and low serum antibody titres.

Adolescent↗
PubMed1985

"Localized" leishmania lymphadenitis: a light and electron microscopic study.

Nineteen cases of "localized" leishmania lymphadenitis without any evidence of visceral leishmaniasis are reported. Fifteen males and 4 females aged 5 to 30 years have presented with localized lymphadenopathy of up to 3 months duration. The disease has a seasonal incidence of late summer to mid-winter. Cutaneous leishmaniasis even when present, usually was overlooked. Lesions of cutaneous leishmaniasis were absent in 3; healed in 1; small, similar to insect bites in 5; classic in 3; lupoid in 1 and unknown in 6 patients. Serum leishmanial antibody determination by IFAT performed on 12 cases were positive. Toxoplasma serology was negative. Histological picture of one lymph node biopsy showed an (anergic) intact histiocytic response characterized by thousands of intracellular amastigotes, no necrosis and inconspicuous plasma cells. In 17 biopsies the picture was that of histiocytic granulomata with varying degrees of necrosis, moderate numbers of amastigotes in several foci, fibrosis and varying numbers of plasma cells. One biopsy from a lupoid case shows numerous epitheloid granulomata, no organisms, no necrosis and inconspicuous plasma cells. Electron microscopy has been performed on 8 biopsies to confirm leishmania amastigotes. Differential diagnosis from toxoplasmosis and cat-scratch disease is discussed. Histological types of responses in the lymph nodes are comparable to those described in cutaneous leishmaniasis: an anergic response with intact macrophage granuloma, a histiocytic response with necrosis, and a lupoid type of response with epithelioid granulomas.

Adolescent↗
PubMed1980

Argentaffin cells, intestinal metaplasia and antral metaplasia in carcinoma of the gall bladder.

The occurrence of argentaffin cells, intestinal metaplasia, and antral metaplasia has been studied in 20 gall bladders with carcinomas, in a papilloma, and in 20 specimens of cholelithiasis. Argentaffin cells were present in six carcinomas, but in only one specimen were they present in large numbers. Only one adenocarcinoma contained occasional argyrophil cells and no argentaffin or argyrophil cells were seen in the papilloma. Five of the 20 specimens of cholelithiasis contained occasional argentaffin cells. Intestinal and antral metaplasia were found in four carcinomas, in the papilloma, and in seven of the 20 specimens of cholelithiasis. It is suggested that metaplastic changes may play a role in the pathogenesis of carcinoma of the gall bladder.

Carcinoma in Situ↗
PubMed1979

Prayer nodules.

Explore the source record for details and available documents.

Aged↗
PubMed1977

Sex-chromatin in Iranian newborn females.

The incidence of sex-chromatin-positive cells during the first five days of life was investigated in buccal smears stained with aceto-orcein in three groups of newborn females: 51 term infants, 17 small-for-date prematures and 9 prematures with birth weight appropriate for gestational age. In addition, single buccal smears were obtained from a control group of 50 older female children. No significant difference was found in the number of sex-chromatin positive cells between the three groups of infants. The mean incidence of sex-chromatin-positive cells in the neonatal period was lower than that of the older control girls, as has been reported by previous workers. The mean incidence of sex-chromatin-positive cells on the fifth postnatal day never reached 17% which was the mean frequency of sex-chromatin positive cells in older controls. This contrasts with the findings of other workers who reported the rise of sex-chromatin positive cells to occur on the second or third days of life.

Cell Count↗
PubMed1972

Immunoglobulin levels in infantile pneumocystosis.

Two hundred and twelve determinations of IgA, IgG, and IgM were performed in 50 infants during an epidemic of interstitial plasma cell pneumonia. Criteria for diagnosis are discussed. The immunoglobulin levels in pneumocystic, non-pneumocystic, and normal American infants are compared. An analysis of the findings in individual cases reveals a time-related immunoglobulin response, which helps to elucidate the pathogenicity of the disease.

Adult↗