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Biomedical subjects

B Anderson

Publications and source records attributed to B Anderson.

At least 415 records · Page 23Linked to original sources
PubMed1977

Myometrial invasion and hysterography in endometrial carcinoma.

One hundred and seventy-nine patients with endometrial carcinoma underwent hysterography as part of their pretreatment evaluation. One hundred and twenty-six women received preoperative irradiation followed by hysterectomy; 30 had surgery alone; while 23 received radical radiotherapy. We have classified hysterograms by the degree of tumor invasion suggested radiographically and have compared these, in the operated cases, with postoperative pathologic examination. Characteristically, lesions confined to the endometrium, or with superficial myometrial penetration, demonstrate either no radiologic abnormality or a small, shallow defect by hysterogram. In those patients with deep myometrial invasion of cancer, hysterograms usually demonstrate a large defect in the endometrial cavity. We believe that hysterography helps assure optimum treatment of each individualized case by helping to determine the volume of tumor and extension into the myometirum.

Female↗
PubMed1976

Myelinated nerve fibers and severe myopia.

Two 4-year-old boys, one white and one black, had unilateral extensive myelinization of retinal nerve fibers associated with severe myopia, esotropia, and amblyopia. The finding of unilateral extensive myelinization of the nerve head and retinal fibers in a child may indicate a potentially remediable anisometropic amblyopia.

Child, Preschool↗
PubMed1976

Spontaneous renal allograft rupture without rejection: a case report.

A case of spontaneous renal allograft rupture is described. Typically, this infrequent transplant complication occurred in the early post-transplant period in an oliguric setting with progressive pain, tenderness and swelling at the transplant site associated with hypotension and a decreasing hematocrit. Prompt surgical exploration and repair of the defect in the convex border of the renal allograft controlled hemorrhage and resulted in graft survival, and a normal blood urea nitrogen and creatinine 10 months after transplantation. There have been no rejection episodes and the renal biopsy demonstrated no evidence of rejection or acute tubular necrosis. Ice preservation for 24 hours and changes secondary thereto may have made the kidney susceptible to rupture when the position of acute flexion was assumed.

Adult↗
PubMed1976

Aggression in captive pigtail monkey groups: effects of provision of cover.

To assess the influence of provision of "cover" on aggressive behavior in captive nonhuman primate groups, concrete cylinders were introduced into rooms in which six groups of pigtail monkeys resided. Basal incidence of aggression was measured prior to introduction of the cylinders and during their presence in the rooms. Four groups, which underwent little or no change in group composition during the study, exhibited substantially less aggression when cover was available than when it was not. Moderate and extreme changes in group composition occurred in two groups; these changes resulted in slight and dramatic increases in aggression, respectively, at the times when the changes occurred. Subjects frequently used the cylinders to avoid the concrete cylinders resulted in decreased aggression in stable groups but did not prevent aggression in groups which underwent moderate or extreme social change.

Aggression↗
PubMed1975

Effect of osmolarity on intracellular pH of rat diaphragm muscle.?22.

To investigate the effect of altered extracellular osmolarity on cell pH, intact rat diaphragms were incubated in a Krebs-Ringer bicarbonate solution. Cell pH was measured simultaneously by weak-acid (pH DMO) or weak-base (ph nicotine) distribution. When osmolarity was raised by mannitol addition, cell water decreased 5-10% (P smaller than .01) while both pH DMO and pH nicotine increased (P smaller than .01) under acid, normal, and alkaline external pH conditions. Hyperosmolarity of identical degree caused by urea resulted in no changes in either cell water or cell pH. Identical amounts of mannitol added to the bath in the absence of external osmolar changes resulted in no changes in either cell water or cell pH. When extracellular osmolarity was lowered by decreasing sodium chloride concentration, cell water increased 10-12% (P smaller than .01). Despite this large change in cell water, no changes in pH DMO or pH nicotine occurred. These data indicate that osmolar induced alterations in cell water only partially explain cell pH changes found in abnormal osmolar states. Alterations in passive and active hydrogen ion transport must also play significant roles.

Animals↗
PubMed1975

Effect of volume expansion on renal citrate and ammonia metabolism in KCl-deficient rats.

When rats with desoxycorticosterone acetate (DOCA)-induced potassium chloride deficiency are given sodium chloride there is simultaneously a partial correction of metabolic alkalosis and a marked reduction in urinary citrate excretion and renal citrate content. To examine DOCA's role in this phenomenon and to determine how sodium chloride alters renal metabolism, rats were made KC1 deficient using furosemide and a KC1-deficient diet. Renal citrate and ammonia metabolism were then studied after chronic oral sodium chloride administration or acute volume expansion with isotonic mannitol. Although both maneuvers partially corrected metabolic alkalosis, sodium chloride raised serum chloride concentration while mannitol significantly decreased it. Urinary citrate excretion decreased to 10% of control in rats given NaCl and to 50% of control in rats infused with mannitol. The filtered load of citrate was constant or increased indicating increased tubular citrate reabsorption. Renal cortical citrate content also decreased approximately 50%. Renal cortical slices from KCl-deficient rats incubated in low or normal chloride media produced equal amounts of 14CO2 from (1, 5-14C) citrate. In addition, urinary ammonia excretion increased by over 300% in both groups. This occurred in the mannitol group despite increased urinary pH and flow rate indicating a rise in renal ammonia production. It seems that neither DOCA nor an increase in serum chloride concentration explains the experimental results. Rather, it appears that volume expansion is responsible for increased renal tubular citrate reabsorption and renal ammonia production. As these renal metabolic responses ordinarily occur in response to acidosis, the data are consistent with the hypothesis that volume expansion reduces renal cell pH in 3KCl-deficient rats.

Ammonia↗
PubMed1975

Nursing behavior of infant pigtail monkeys (Macaca nemestrina): preferences for nipples.

Nursing behavior of 56 singleton infant pigtail monkeys (Macaca nemestrina) was monitored. Infants over 1 mo. of age showed strong preferences for one of their mothers' nipples, while few infants less than 1 mo. old did so. The infants which had the lowest birthweights for each sex showed no clear preference even though they were older than 1 mo. A trend toward lateral preference (for the right nipple) was identical for male and female infants. Analysis of the development of preference for nipple may provide useful information of assessing development progress.

Animals↗