Search PubMed⌕ Search

Biomedical subjects

A Wolff

Publications and source records attributed to A Wolff.

At least 109 records · Page 6Linked to original sources

[The mode of action of bacteriocin N5 purified from Clostridium perfringens].

The purified bacteriocin N5 produced by Clostridium perfringens BP6K inhibited simultaneously the syntheses of DNA, RNA and protein in sensitive cells, without DNA degradation. Bacteriocin N5 inhibited the accumulation of leucin and caused the exit of the previously accumulated amino acid. The effects of bacteriocin N5 are very similar to those observed for colicins E1, K, A and I.

Bacterial Proteins↗

Microbial content of nonsterile therapeutic agents containing natural of seminatural active ingredients.

The relationship was investigated between various chemical or pharmaceutical production processes and the extent of microbial contamination, of natural origin, of the resulting products. The products contained active ingredients of vegetable, enzymatic, or animal origin. It was concluded that (i) vegetable products practically free from microbes can be produced if the proper manufacturing steps are taken; (ii) sterilization of the media used to manufacture antibiotics, etc., produces products with little contamination; and (iii) products containing extracts of animal organs require careful refrigeration and addition of preservatives to produce acceptable levels of microbial contamination.

Bacteria↗