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Biomedical subjects

A Wilk

Publications and source records attributed to A Wilk.

At least 91 records · Page 5Linked to original sources
PubMed1980

[Treatment of fractures of the anterior arch of the mandible in children (author's transl)].

The ideal treatment for fractures of the mandibular anterior arch is the simplest procedure which ensures reduction, and sufficient stability for satisfactory dental articulation. The forces applied during mastication are in fact of a low degree and there is a minimal risk of secondary displacement; bone consolidation rapidly occurs and effective remodelling of minor articulation disorders is possible in children under 10 years of age. No single technique is applicable in children, and treatment of mandibular fractures in children under 13 is a function of the dental age, and must employ local possibilities for each age group to the best advantage.

Age Factors↗
PubMed1978

Binding of antigen to surface Ig on isolated rat mast cells.

This study concerns observations on isolated rat mast cells sensitized to specific antigen. Specific binding of antigen to the surface immunoglobulins of these cells could be demonstrated by immunofluorescence technique as well as by radiolabelled antigen binding and the degree of binding parallelled the allergic reaction as judged by histamine release. Exposure of mast cells to antigen at both low and high antigen concentrations did not change the distribution of the surface immunoglobulins. Furthermore, neither capping not shedding could be induced, even by excessive antigen stimulation. The amount of antigen molecules bound to surface Ig was linearly correlated to the allergic histamine release. When mast cells were sensitized to two antigens of different molecular weight, the cells showed the highest sensitivity to the antigen having the highest molecular weight. These results indicate that both the amount of antigen and the molecular weight of the antigen bound to surface Ig are important factors in the allergic histamine release from mast cells, whereas surface Ig redistribution is not.

Anaphylaxis↗
PubMed1977

[Facial osteotomies without fixation].

The authors first review the problems associated with inter-maxillary blockage and of classical methods of immobilisation used in all types of facial osteotomy. Their experience of osteosynthesis in traumatology has led them to use whenever possible osteosynthesis alone with screw fixed microplates. The other methods are used only as secondary assistance in the case of necessity. Osteosynthesis without blockage prevents recurrence and does not compromise the result as far as satisfactory dental articulation is concerned.

Alveolar Process↗
PubMed1976

A study of Russell bodies in human monoclonal plasma cells by means of immunofluorescence and electron microscopy.

Five patients with a serum M component were shown to possess plasma cells containing Russell bodies. Four of the patients suffered from multiple myeloma, whereas the fifth probably had a different disease or was in a premyeloma stage. The Russell bodies stained blue with the May-Grünwald-Giemsa stain and were found both in the nuclei and in the cytoplasm of the plasma cells. Ultrastructural studies showed that the Russell bodies were osmophilic and those located in the cytoplasm were always situated within the cisternae of the rough endoplasmic reticulum. The intranuclear Russell bodies were always surrounded by a triple layered membrane, and some evidence was obtained that these bodies were first formed within the perinuclear space of the cells. Immunofluorescence studies using anti-L chain conjugates showed a positive marginate straining of the intranuclear as well as the cytoplasmic Russell bodies of the cells from all patients. Only one patient had cells with Russell bodies which also stained their location in the plasma cells. It is concluded that some plasma cells in multiple myeloma may produce an excessive amount of L chains which, in combination with a failure in the secretion of immunoglobulin molecules, may lead to the formation of Russell bodies.

Adult↗
PubMed1975

[Fronto-malar osteosynthesis by means of screwed plates].

The external orbital apophysis provides a zone of solid anchorage for the treatment of fractures as well as for the immobilization of osseous fragments after facial osteotomy. While proposing new miniaturized material the authors present 45 cases of fronto-malar osteosynthesis carried out in one year. They recall that solid immobilization by plating avoids inter-maxillary blockage, and is the only means of restraint among those presently used which is capable of opposing late post-operative recession. Consequently after facial osteotomy, the plates are left in place for 12 months. They are removed under local anethesia.

Bone Plates↗
PubMedDate not supplied

Use of a new malleable implant as a bone substitute in maxillofacial surgery.

Biocompatible osteoconductive polymer (BOP) has been used since 1979 as a substitute for bone in orthopedic surgery and neurosurgery. To date, in maxillofacial surgery, loss of bone volume as a result of either trauma or osteoporosis has been compensated for by autologous bone onlay graft or subperiosteal apposition grafts of synthetic materials. Neither of these solutions is entirely satisfactory. Autologous bone is subject to reabsorption, requiring initial overcorrection and multiple reoperations to achieve an acceptable result. Preshaped implants of Proplast, Vicryl, Gore-Tex, or silicone do not offer much flexibility, and coral granules and hydroxyapatite are difficult to handle. Finally, all foreign materials can elicit problems with tolerability. In its SP (solution/powder) form, BOP is a paste that can be molded precisely to the required shape, making it ideal for maxillofacial surgery. This study examined the long-term tolerability and facial alterations after implants of BOP in 11 patients who underwent post-trauma and cosmetic surgery.

Adult↗