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Biomedical subjects

A Wessing

Publications and source records attributed to A Wessing.

At least 109 records · Page 6Linked to original sources

[Exudative senile maculopathy, clinical picture, pathogenesis, prognosis and therapy (author's transl)].

From the literature and our own experience it is evident that choriogenic subretinal vascular proliferation is the most important symptom of senile exudative maculopathy. Prior to proliferation a certain percentage of cases develops an isolated detachment of the retinal pigment epithelium. However, there are cases where already in the predisciform stage vascular proliferations are proved histologically. Photocoagulation can be applied to isolated pigment epithelial detachment, to cases with beginning vascular proliferation, and to late stages in order to accelarate the final scaring.

Age Factors↗

Treatment of Coats' disease with photocoagulation.

71 eyes with Coats' disease were treated with photocoagulation. By coagulation of the abnormal vessels the disease process could be halted in 64 eyes over a mean observation time of 2 years and 3 months after completion of treatment. In 51 of these eyes the lipoid deposits regressed. In only 7 eyes a progression of the disease could not be prevented. Complications of photocoagulation treatment were not observed.

Follow-Up Studies↗

Coat's disease. An epidemiologic and Fluorescein angiographic study.

Coats' disease represents a disorder of the retinal vascular walls. In a series of 112 consecutive eyes with Coats' disease the involvement was unilateral in 90.2%. The majority (72%) of patients were male. 57.8% were under 20 years of age. There was, however, a second peak of the disease (30.4%) between the age of 41 and 60. Severe cases were found mainly among juvenile patients, whereas in the senile group milder cases prevailed. Fluorescein angiographic findings comprised vascular aneurysms in almost all cases, rarefaction and coarsening of the capillary bed in 71%, capillary occlusions in 70%, occlusions of arterioles or arteries in 27%, shunt formations in 27%, extensive widening of arteries or veins in 27% and leakage of dye mainly in advanced cases. The participation of the central retina in the disease process was variable. Evidence is presented that Leber's military aneurysm retinitis is not a separate entity but a special form of Coats' disease.

Adolescent↗

[Histoplasmin skin test and focal hemorrhagic chorioiditis (author's transl)].

A histoplasmin skin test was performed on 56 patients with focal hemorrhagic choroiditis. The test was negative in 53 choroiditis patients and positive in three patients. The three patients with posi-ive skin test had been living for a long time in the eastern part of the U.S.A. where histoplasma capsulatum occurs endemically. The results of this study suggest that the infection with histoplasmin capsulatum is not the cause of focal hemorrhagic choroiditis in our area.

Choroiditis↗

[Focal hemorrhagic chorioiditis (author's transl)].

The clinical and fluorescenzangiographic followup of 111 patients revealed, that focal hemorrhagic chorioiditis is a chronic disease with poor prognosis for visual acuity. After a median follow-up period of more than two years, only half of all involved eyes showed inactive scarring of the lesions. In 13% both eyes were involved. Corticosteroids, antiphlogistics and vasoactive drugs had no significant influence on the course of the disease. The therapeutic results with photocoagulation were more favorable. In 15 of 25 photocoagulated eyes a fast and permanent regression of the choroidal proliferations could be achieved.

Adolescent↗