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Biomedical subjects

A Wagner

Publications and source records attributed to A Wagner.

At least 397 records · Page 22Linked to original sources
PubMed1987

Side-effects of cytapheresis with cell separators.

The rate of procedure-related side-effects was evaluated in 11,895 cytaphereses performed with a Haemonetics 30 (H-30) cell processor (2,486 procedures) or with a Haemonetics V-50 (H-50) cell processor (6,813 procedures) or with the Fenwal CS-3000 cell processor (2,596 procedures). The overall rate of side-effects was 7.41% (absolute number 881). There was a significant difference between female and male donors concerning the frequency of hypotension episodes and citrate toxicity related reactions. There were also distinct differences between the single cell separator types concerning the frequency and type of side effects. Hypotension episodes and citrate-related reactions were observed most frequently during cytapheresis with the H-30 (7.65 and 2.96% respectively). Venous access and technical problems appeared more often when the H-50 or the CS-3000 were used. Thus both the H-50 as well as the CS-3000 cell separators allow safe cytapheresis with a low number of side-effects.

Austria↗
PubMed1986

[Incidence of neuropathies in so-called rheumatoid vasculitis].

40 patients with so-called rheumatoid vasculitis, a special form of the course of rheumatoid arthritis with high rheumatoid titres and inclination to extraarticular organ manifestation were clinico-neurologically and electro-diagnostically examined. Neurologically in 10 patients a neuropathy was found, in which case polyneuropathies numerically prevailed. By means of the additional electromyographic and electroneurographic examination in altogether 75% of the patients pathological findings and thus a participation of the peripheral nervous system could by proved. The aetiology of the individual disturbance of the nerve function remains open. Questions of the pathogenesis are discussed.

Arthritis, Rheumatoid↗
PubMed1986

Relationship between childhood hyperactivity and accident proneness.

Previous research suggested that hyperactive children are especially susceptible to accidents. Two questions remain: is the relationship peculiar to hyperactivity in childhood or for behaviorally disturbed children in general and does the relationship hold for females as well as for males? To answer these questions 189 patients at a child psychiatric clinic were rated on a scale which included measures of hyperactivity and accident proneness. The hyperactive patients were more likely to be described as accident prone than nonhyperactive patients. The relationship between childhood hyperactivity and accident proneness is confirmed and is specific. The relationship holds for both boys and girls.

Accident Proneness↗
PubMed1986

Deuterioglucose: alteration of biodistribution by an isotope effect.

Carbon-14 glucose, in which all carbon-hydrogen bonds were replaced by carbon-deuterium bonds (deuterioglucose), was extracted from algae growing in heavy water and exposed to [14C]carbon dioxide. The identity of [14C]deuterioglucose was confirmed by comparison with authentic material on two high performance liquid chromatography and two thin layer chromatography systems. Fermentation to lactate followed by oxidative decarboxylation demonstrated that 35% of the 14C was on carbons 3 and 4 for deuterioglucose isolated from a 24-hr algal incubation, and 61% for a 20-min incubation. Mice were injected intravenously with either (24-hr) deuterioglucose or with 14C-labeled (protio)glucose labeled uniformly. The deuterioglucose cleared more slowly from the blood, while heart and brain accumulated label more slowly. Tissue concentrations peaked at later times for deuterioglucose. Deuteration may be a useful feature of radiopharmaceutical design.

Animals↗
PubMed1986

[Problems in the topographic diagnosis of bilateral abducens pareses].

It is not possible to exactly differentiate bilateral abducent paralysis case topographically into those arising peripherally and those from the brain stem by means of clinical data. The application of electrophysiological methods, especially the acoustically evoked brain stem potentials and the oculo-auricular phenomena, greatly increases the accuracy of topographical diagnosis. If the oculo-auricular reaction can be triggered in the normal way, a lesion of the brain stem may be practically excluded, whereas changed acoustically evoked potentials at an early point may indicate a disturbance of function in the core region of the 6th cranial nerve.

Abducens Nerve↗