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Biomedical subjects

A V Guliaev

Publications and source records attributed to A V Guliaev.

At least 37 records · Page 2Linked to original sources

[Cytogenetic and medical genetic research on families with a high predisposition for the development of cancer of the gastrointestinal tract].

Three families suspected of predisposition to tumor development in the gastrointestinal tract have been followed in a medico- and cytogenetical study. According to genealogical analysis, cancer predisposition was confirmed in one family only. However, both specific and non-specific signs of genome instability and possible malignant transformation of cells were identified in members of the other two families.

Adolescent↗

[Simultaneous intrapleural resection of malignant tumors of the esophagus and cardioesophageal region].

Results of transpleural resection of esophageal and cardioesophageal tumors in 115 patients are discussed. Extensive combined access, formation of invagination anastomosis, preoperative preparation and intensive therapy for correction of homeostasis proved the basic elements of the therapeutic modality. The use of these elements assured lower postoperative lethality (13.9%), particularly, due to surgical complications (9.3%). In patients undergoing extensive combined resection, lethality rate was 10.0%. Intrapleural anastomosis failed in 5.7%.

Adenocarcinoma↗

[Operative interventions on the urinary tract in combined surgical treatment of cancer of the rectum and sigmoid].

Immediate and long-term results of 28 combined operations for carcinoma of the distal part of the colon with resection of different portions of the urinary system are thought by the authors to justify such interventions even in a real spread of tumour to the adjacent organs. A wider range of resectability does not exert a negative effect on immediate and long-term results of the surgery. Complications due to a wider volume of surgery are noted rarely and never result in lethal outcomes. The incidence of recurrences and metastases in the group of patients subjected to combined operations is the same as compared with typical interventions.

Adult↗

[Surgical prophylaxis of peritonitis and other suppurative-inflammatory complications following intra-abdominal resections in cancer of the large intestine].

The report discusses a surgical procedure for prevention of pyo-inflammatory complications and peritonitis tested experimentally in 21 rabbits and clinically in 44 patients with colorectal cancers. The frequency of pyo-inflammatory complications was reduced following a reinforcement of anastomosis sutures with autoplastic materials in a procedure employing extraperitonization.

Animals↗

[Diagnostic errors and inadequate therapeutic tactics in tumors of the large intestines].

The authors observed 21 patients after previous non-radical treatment in other medical institutions. The age of the patients was from 38 to 80. Radical operations were performed on all the patients during relaparotomies. The authors make a conclusion that choice of a rational surgical and curative tactics in colonic tumors was determined individually with special reference to the general state of the patient, careful assessment of the degree of local spread of the tumor. A dogmatic approach is thought to be inadmissible.

Adult↗

[Laparoscopy in oncological practice].

The results of an analysis of laparoscopy performed in 204 patients for neoplasms of the peritoneal cavity, retroperitoneal space and lung carcinoma are presented. Laparoscopic findings were confirmed by subsequent surgery in 166 cases. These findings in lung cancer patients were compared with the results of a previous radionuclide examination of the liver, laparoscopic diagnosis being confirmed in 66.6%.

Diagnosis, Differential↗

[A method of treating villous tumors of the rectum].

A method of dissection of the rectum mucosa together with the tumor is described. The mucosa defect is closed by bringing the mucous membrane down and putting stitches on all the circumference. Successful operations were performed on 7 patients.

Female↗

[Surgical prevention of peritonitis in resection of the colon for cancer].

A method of biological hermetization of the anastomosis by a peritoneal graft on the feeding pedicle is described which was used in 35 patients with carcinoma of different parts of the colon. There was no incompetent enterocolostomy in the patients following different kinds of resections of the colon. The proposed method does not make the operation longer.

Colectomy↗

[Lumbar-pelvic lymphadenectomy in the treatment of rectal cancer].

Extensive radical operations with the ablation of lymph nodes of the pelvis and lumbar region were fulfilled in 64 patients with rectum carcinoma. Prior to the operation all the patients were subjected to the inferior direct roentgen-contrast chromolymphography. High reliability of the negative conclusions of roentgen-contrast lymphography is shown. The positive results of the examination are less reliable. Twelve patients had histological evidence of metastases of the tumor in lymphatic nodes of the second and third stages of the lymphogenic spread of the carcinoma of the rectum. The extended volume makes the operation more radical.

Adult↗

[Choledochotomy and the methods for its performance].

The authors have made 390 operations on ductus choledochus. Indications for choledochotomy were choledocholithiasis, jaundice, cholangitis and others. The ideal choledochotomy was fulfilled in 7,1% of cases as a completion of diagnostic manipulations on the duct. The external drainage of ductus choledochus was performed in peritonitis, severe cholangitis and inflammatory alterations of the hepatoduodenal ligament and in weak senile patients (mortality--11,7%). Multiple stones and great dilatation of the duct (mortality--4,5%) were considered to serve indications for supraduodenal choledochoduodenostomy (38,7%). Papillotomy was made in fixed ampula stones, stenosis of Vater's papilla (18,2%). Lethality in such cases was twice as high as after choledochoduodenostomy (8,5%). The authors believe peritonitis and duodenostasis to be contraindications against the internal drainage of biliary ducts.

Ampulla of Vater↗

[Primary suture of perineal wound after extirpation of the rectum in rectal cancer].

A comparative estimation of a hermetic suture of the perineal wound in 53 patients and its tight tamponade in 68 patients after extirpation of the rectum for cancer is given. Primary suture may and should be employed during this operative procedure in the absence of diffuse bleeding from the lesser pelvis walls and a damage of the intestine. Hermetic suture of the wound shows some outright advantages: the possibility for patients' rising from bed in earlier terms prevents the occurrence of complications and contributes to shortening of the postoperative period.

Adult↗