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Biomedical subjects

A Tanguy

Publications and source records attributed to A Tanguy.

At least 55 records · Page 3Linked to original sources

[False images of foreign bodies of plant matter in the limbs of children. Apropos of 3 case reports].

Vegetal foreign bodies in the limbs cannot be demonstrated by X-ray examination and may lead to erroneous diagnosis. The answer should be given by surgical exploration, however, and this is particularly true for mobile foreign bodies in the joint, a high degree of suspicion is necessary at surgery. Three observations are presented in this paper which emphasize practical recommendations to perform without delay the simple efficient surgical procedure consisting in removal of the foreign body.

Adolescent↗

[Appendicular cystic pneumatosis. Apropos of a case].

The case of a 3-year-old girl with pneumatosis cystoides of the appendix is reported. Pneumatosis cystoides intestinalis is an uncommon disease, particularly in the appendiceal localization and in the young child. Despite of the benign nature of the disease, we emphasize the need of an early diagnosis by systematic histological examination of the removed appendices. The etiopathogenesis is obscure.

Appendicitis↗

Dilatation of the subarachnoid pericerebral space and absorption of cerebrospinal fluid in the infant.

The authors investigated intracranial pressure, resistance to cerebrospinal fluid (CSF) absorption following ventricular infusion and radiopharmaceutical absorption of radionuclide injected into the ventricles in two infants with dilatation of the subarachnoid pericerebral space. The results of this study showed an increased resistance to CSF absorption. Intraspinal CSF absorption was seen to predominate, as shown by isotopic cisternography.

Cerebrospinal Fluid↗

Biomechanical properties of spinal ligaments and a histological study of the supraspinal ligament in traction.

This paper reports the results of a biomechanical study of 43 human spinal ligaments from fresh cadavers and living subjects. Tensile tests were performed with an original testing machine. The tension load and relaxation were applied at the same constant slow rate (1 mm min-1) on entire ligaments. In order to avoid ligament injuries, fixation in the apparatus was on the bone held in clamps specifically designed for each bone, never the ligament itself or its bony attachments. All the load-deformation curves had a sigmoid shape and during load-unload cycles ligaments exhibited elastic properties. This was particularly evident for the ligamentum flavum. The intertransverse posterior longitudinal ligament and the ligamentum flavum were the most resistant. The elongation-tension curve pattern may be explained by the microscopic architectural change that was studied in supraspinous ligament.

Adult↗

[Unusual late disclosure of left congenital diaphragmatic hernia].

A posterolateral hernia through Bochdalek foramina was discovered in a 27 months old child under unusual circumstances. During lifting an heavy weight, migration occurred of the abdominal content through the foramina into the left thorax. The size of the pleuroperitoneal communication was well demonstrated by peritoneography. Possible rupture of a diaphragmatic relaxation was eliminated on findings at surgery. Reconstructive surgery led to an uneventful recovery which is the rule in this type of late-discovered hernia.

Child, Preschool↗

[Cervical tumors of thymic origin in children].

Cervical tumors of thymic origin are exceptional and can be either cystic or solid. The embryogenesis of the thymic gland explains the cervical location of these tumors. The authors present two cases in which the clinical picture was limited to cervical masses with very few symptoms. Treatment consisted of surgical removal. Subsequent course was uneventful without any immunological deficit or myasthenia.

Child↗

Radiotherapy as an integrated part of the treatment of soft tissue sarcomas.

A considerable improvement in the prognosis of soft tissue sarcomas in the adult has been obtained with a treatment schedule combining surgery and routine radiation therapy (possibly preoperative and certainly postoperative); local recurrences, the predominant element in the natural history of the disease, have become very rare and limb function is generally maintained. Metastatic risk presents the major problem, and in our series spread of the disease remained uncontrolled in 25% of cases. Further research is required in this area, and a better definition of the risk factors, especially with regard to histology, is needed. We suggest that the possibility of reinforcing treatment of those histological forms at high metastatic risk by the introduction of multidrug therapy after local treatment be investigated. Such studies can only be effectively conducted within the framework of a multicenter collaborative controlled clinical trial.

Female↗

[X-ray computed tomography of intracranial fluid cavities in the infant (ventricles, the interhemispheric fissure and pericerebral spaces)].

The brain of 102 infants with an age range of 0,5-22 months was examined with computed tomography (C.T.). The main indications for C.T. investigations were psychomotor retardation or seizures. There were 70 infants with an increase of the volume of intracranial cerebrospinal fluid characterized by -a pericerebral effusion with a thickness from 1-14 mm -a dilatation of interhemispheric fissure -and most frequently an internal hydrocephalus. This phenomenon and his spontaneous remission suggested, that if arachnoïd will are observed in new-born infants, they increased in complexity with normal function as development proceeded.

Brain↗

[Talo-calcaneal continuity. Myth or reality?].

On the basis of two separate biomechanical studies of talus and calcaneus, the authors show: the absolute continuity of the trabecular structure of these bones, the mechanical behaviour characterised as "fragile" for the talus and "intermediate" for the calcaneus, superficial strains underload: by photoelastic studies, they are show to be in reversed phases both on their lateral and medial sides. Authors conclude that these two bones act together as sectional across which collect dispach and absorb transmitted forces during gate.

Adult↗

[Anatomical study of a human case of total celosomia].

The authors studied a human specimen delivered at 36 gestational weeks and presenting with a caelosomia. The various abnormalities could be classified as: superior caelosomia: ectocardia, diaphragmatic hernia; middle caelosomia: liver outside the abdominal cavity, mesenterium commune O, meso-hepato-cave; inferior caelosomia: cloacal extrophia. In addition to the forementioned abnormalities, a lumbosacral meningocele and multicystic kidneys were found. All these abnormalities are exceptionally found all together in one human specimen and this monster might be classified in the total caelosomia group.

Abdomen↗

[Combination chemotherapy with vincristine, melphalan, CCNA, cyclophosphamide, prednisone in myeloma].

The authors report the results of a prospective, multi-centre trial involving 87 patients with previously untreated myeloma who were treated by combination chemotherapy consisting of melphalan, cyclophosphamide, CCNU, prednisone and vincristine. 83.1% of patients had a high tumour mass (stage III on Durie and Salmon's classification). The response to treatment could be evaluated in 76 patients and 70% were found to respond. The median actuarial survival of the whole population is 30 months. The survival is significantly longer (p less than 0.001) in responders (median 40 months) than in non-responders (median: 17 months); the survival is significantly shorter (p less than 0.01) in subjects with renal failure (median: 10 months) than in subjects without renal failure (median: 36 months). This treatment is sufficiently well tolerated to be administered on an outpatient basis. One case of acute monoblastic leukaemia was observed. These results are similar to those reported in the literature.

Antineoplastic Combined Chemotherapy Protocols↗

Surface electrical stimulation in the treatment of idiopathic scoliosis: preliminary results in 30 patients.

From 1978 to 1981, 30 patients have been treated for idiopathic scoliosis with surface electrical stimulation using the E.S.O. (Electro Spinal Orthosis) Single Channel designed by Medtronics. The criteria for selection were: patients who were skeletally immature; single thoracic, thoracolumbar or lumbar curvatures between 30 degrees and 40 degrees; or the same curve pattern greater than 20 degrees with 5 degrees of documented progression in one year; patient and family reliability. Patients with previous treatment were excluded from the study. No one was more than 15 years of age. Curve amplitude was between 25 degrees and 35 degrees in 72% of the patients. Curve pattern was single thoracic in 28 patients, thoracolumbar in one, and lumbar in one. Five patients were excluded from the evaluation of the results of stimulation of the correction of the curve. Of the 25 patients remaining, one was improved, 14 were stable, two had mild acceptable progression (less than 10 degrees with no need for further treatment), and eight had an unacceptable progression greater than 10 degrees requiring some form of alternative treatment. The authors conclude that significant improvement in the curvatures under treatment was extremely unlikely, that progression may have been stopped in some curves, that the curvatures under 30 degrees had the best results, and that curvatures that do not respond to surface electrical stimulation are not likely to respond to a Milwaukee brace treatment.

Adolescent↗

[Fractures of the femoral shaft in children. Apropos of a homogeneous series of 97 fractures].

The authors have analysed the results of 97 fractures of the femoral shaft in children. In 75 instances, the treatment was conservative-traction followed by a plaster cast after three weeks. The reduction was satisfactory in only 19 cases. The plaster cast did not prevent secondary displacement. After surgical treatment, complications were observed in one third of the cases. The review of the cases with a long follow up showed that with growth, there was good remodelling. In 95 p. 100 of the children there was no loss of function detectable by the family, and only a careful clinical and radiological examination was able to demonstrate some sequelae.

Adolescent↗

[Anatomic and histologic study of the human ileocecal valve. Developmental aspects as a function of age].

Based on gross anatomy and histological studies of thirty specimens ranging from nineteen weeks of gestational age to eighty-two years old, the authors present an analytical study of the ileocecal valve. The results confirm the evolutive aspect of the ileocecal valve with age, but, however seems to demonstrate a functional regression correlated with the frequency of its incontinence in adulthood.

Adolescent↗

[Value of herniography in the therapeutic management of inguinal hernias in young girls. Apropos of 148 cases].

The authors report a study on 148 female children demonstrating clinical evidence for inguinal hernias. The diagnosis was evaluated using Ducharme-Bensoussan's procedure for herniography hernia was documented in 143 cases, so which 44% revealed genital tract content. Eight cases produces unrelated pathological findings, especially crural hernia, nephro-uropathy diaphragmatic hernia. However, the main interest of the procedure is in evaluating the controlateral inguinal canal. Whereas three infants presented with bilateral symptoms, bilateral hernia was proven in 66 cases (46,2%) by herniography. In this way, the procedure is a sure way to ensure that hernia is really unilateral and to prevent any controlateral recur in the coming months.

Child↗