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Biomedical subjects

A Schulze

Publications and source records attributed to A Schulze.

At least 145 records · Page 8Linked to original sources
PubMed1989

High frequency oscillatory and conventional mechanical ventilation in experimental surfactant deficiency: a study using a new infant ventilator technique.

The performance of a new infant ventilator system had to be evaluated. Technically it is characterized by flow (V)- and pressure (P)-transducers mounted immediately near the endotracheal tube. A microcomputer works as a function generator and governs servo-controllers for V and P thus offering a multiplicity of different modes both of the conventional (CMV) and high frequency oscillatory (HFO) type. The additional dead space imposed by the system is identical with its internal compressible volume of 2 ml. Serial pulmonary lavages were performed in 17 adult rabbits while on CMV. PaO2 per unit of mean airway pressure (MAP) decreased thereby from 95.9 +/- 29.3 to 9.0 +/- 6.7 (kPa/kPa). The animals were then alternately ventilated by HFO (5, 10, or 20 Hz) and CMV, at matched MAP's. No significant difference in PaO2 between the two methods was revealed in intra-animal comparisons except a slight superiority of CMV at MAP's above 1.7 kPa (P less than 0.05). There was no clear linear relationship between PaO2 and MAP both at CMV and HFO. A strong increase in PaO2 often occurred beyond a MAP threshold. In 37 postlavage HFO runs at 5 Hz in 13 animals volume amplitudes of 3.19 +/- 0.5 ml/kg of bodyweight resulted in PaCO2 levels of 6.29 +/- 1.87 kPa. Except in one experiment (10 Hz) volume amplitudes below the natural dead space produced arterial hypercapnia.

Animals↗
PubMed1989

[The effect of early childhood experiences on neurotic disorders in the adult].

"Empiricists" and "clinicians", in especial those in the field of psychoanalysis, have reached divergent views on the significance of early childhood experiences for neurotic affections in the adult. The present paper discusses the need to resolve such "apparent" differences. To be effective, models of psychological development should, besides taking into account biological hereditary influences and the psychosocial conditions of childhood, also consider the ongoing perpetualisation of neurotic behavior through social feedback.

Adolescent↗
PubMed1988

[Torticollis spasmodicus and addiction].

From a random sample of 49 patients suffering from torticollis spasmodicus and dependence on alcohol or medicaments, 6 have been selected and are discussed with i view to findings possible mutual influences between the disorders. In particular, premorbid accentuation of personality presented itself as a potential risk factor leading to both tortocollis and alcoholism. In various cases, the patient makes use of alcohol for self-treatment of extrapyramidal-motor symptoms. But such phenomenological developments are preceded by varied constellations of conditions, that have to be taken into account in the treatment.

Adult↗
PubMed1988

[Catamnestic studies of patients with writer's cramp following inpatient psychotherapy].

The paper gives the results of a follow-up study of 58 patients after psychotherapeutic treatment as in-patients for writer's cramp. Where as immediately after discharge 74.1% of the patients felt an improvement in their condition, at the time of the follow-up study only 17.2% were demonstrably improved, with 37.9% subjectively feeling an improvement over their state before treatment as in-patients. These results suggest that the customary psychotherapeutic methods employed have less effect on the evidently multifactorial extrapyramidal-motor basic complaint but rather have the effect of improving the patient's ability to cope with this in daily life.

Adolescent↗
PubMed1988

[Changes in functional cerebral laterality of patients with torticollis spasmodicus].

By comparing the results of tapping with and without simultaneous speaking and by evaluating their lateral differences the probable lateralization of functional speech centre was established in 28 patients with torticollis spasmodicus and 28 healthy controls. In doing this, it became evident that unlike the controls the patients as a hole in a significant way lateralized the speech centre more frequently to the right. The changed cerebral laterality in the patients was supposed to be stimulated by pronounced emotional conflicts and to be involved in the disease of torticollis spasmodicus.

Brain↗
PubMed1987

Isolation and characterization of esters of indole-3-acetic acid from the liquid endosperm of the horse chestnut (Aesculus species).

Esters of indole-3-acetic acid were extracted and purified from the liquid endosperm of immature fruits of various species of the horse chestnut (Aesculus parviflora, A. baumanni, A. pavia rubra, and A. pavia humulis). The liquid endosperm contained, at least 12 chromatographically distinct esters. One of these compounds was purified and characterized as an ester of indole-3-acetic acid and myo-inositol. A second compound was found to be an ester of indole-3-acetic acid and the disaccharide rutinose (glucosyl-rhamnose). A third compound was partially characterized as an ester of indole-3-acetic acid and a desoxyaminohexose.

Chromatography↗
PubMed1987

[Psychopathologic symptoms in torticollis spasmodicus].

The paper presents the results of detailed diagnosis of 51 patients with torticollis spasmodicus. A discussion of the results would seem to indicate the possibility of there being one group with prior neuroses, one group compulsive in nature, and one group whose diminished performance arises from the condition of the brain. Reliable diagnosis is only possible when both mental and physical parameters have been taken into consideration.

Adult↗
PubMed1987

Pathogenetic significance of venous hyperoxaemia in retinopathy of prematurity.

Ten underweight newborns with severe retinopathy of prematurity (ROP) and 18 newborns with slight changes in the sense of ROP were compared with 66 healthy infants. The distribution of 13 possibly pathogenetically effective features in these 3 groups of patients was studied by means of variance analysis. The greatest significance resulted for multiple blood transfusions and exchange transfusions. From this it was concluded that the toxic oxygen effect on the immature retina was probably more dependent on the venous PO2 (determined by Hb concentration, O2-affinity, arterial PO2, and blood flow) than on the isolated arterial PO2.

Analysis of Variance↗
PubMed1986

Possible effects of organelle charge and density on cell metabolism.

To respond to gravity a biological system must: First, perceive the stimulus; and, second transduce the stimulus into an appropriate response. This laboratory has studied a system of perception and transduction involving the gravity-induced asymmetric distribution of a plant growth hormone. From these studies we have developed a working theory which states as its postulates that: a) The perception of the gravitational stimulus involved a perturbation of the plant's bio-electric field; and b) that the transduction of the stimulus involved voltage-gating of hormone movement from the plant's vascular tissue into the hormone responsive growing tissue. These studies may provide the simplest system for studying [correction of studing] the mechanism whereby the gravity signal is translated into a biological response.

Biological Transport↗
PubMed1985

Estimation of indole-3-acetic acid in gametophytes of the moss, Physcomitrella patens.

By means of gas chromatography-selected ion monitoring-mass spectrometry using an isotope-dilution assay with 4,5,6,7-tetradeutero-indole-3-acetic acid as the internal standard, indole-3-acetic acid has been estimated to be present in aseptically cultured gametophytes of wild-type Physcomitrella patens (Hedw.) B.S.G. at a level of 0.075 microgram g-1 dry weight or 2.1 ng g-1 fresh weight.

Bryopsida↗