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Biomedical subjects

A Schaefer

Publications and source records attributed to A Schaefer.

At least 127 records · Page 7Linked to original sources
PubMed1976

[Recovery after fasting in the rat placed either on spontaneous diet choice or on imposed diet conditions].

During recovery from a five days' fasting, rats fed with separately presented glucids, proteins and lipids, show a 22 days' increase of the total caloric intake, and thus the fasting caloric lack is exactly compensated. On the contrary, rats fed with choice between proteins or glucids-lipids mixture (with various ratios) do not show such an increase, and thus do not compensate. The conclusion is, that the alimentary conditions are determinant in these kinds of experimentations.

Animals↗
PubMed1975

[Effects of glucose, aminoacid or lipid infusion on dietary self-selection in the rat].

Rats with an intracardiac chronic catheter were offered dietary self-selection between glucids, proteins and lipids intakes. They are infused continuously with 0.9% NaCl except on the test day with glucose, amino acids or lipids. Parenteral load is about 25% of the daily total food intake. With glucose infusion a selective decrease in glucids intake is observed of about 80% of the caloric glucose load. Aminoacidemic and lipidic infusions lead not only to decrease respectively in proteins and lipids intakes, but also in glucids intakes. So, in this case, total caloric intake decreased more than caloric load. Results are discussed in the hypothesis of existence of a hepatic chemosensibility.

Amino Acids↗
PubMed1975

[Seasonal fluctuations of food intake and bodyweight in the dormouse Glis glis (author's transl)].

Cycles of body weight lasting a few weeks occurred in dormice fed ad libitum, throughout the year with the same food. The pattern of the fluctuations suggests an oscillation between an upper and a lower limit. When the lower limit is reached, compensatory mechanisms acting on the food intake are induced which cause an increase in body weight to the upper one; when this upper limit is reached, other mechanisms cause the body weight to decrease to the lower one. Thus, body weight and variations in food intake may well be controlled by the difference between the body weight and the limit it will reach. In a warm environment (23-25 degrees C) these fluctuations are smaller than in the cold (5-6 degrees C). They are also smaller during summer than during winter in animals placed in natural climatic conditions. In summer, the body weight stays near the upper limit; in this season, as in the warm environment, the lower limit approaches the upper one. Thus, the main circannual variation of body weight regulation in dormice may be the elevation during summer of the lower body weight limit.

Animals↗
PubMedDate not supplied

Acute versus chronic conditions for studies of fetal nutrient requirements: applicability to the human.

In order to validate results obtained in 'acute' versus 'chronic' experimental conditions, two fetal sheep nutrients, lactate and glucose, have been determined in 'acute' conditions and compared with the 'chronic' data in the literature. Maternal and fetal blood glucose in 'acute' conditions was in the range of published 'chronic' data. Fetal blood lactate was similar in 'acute' and during 'chronic' conditions. Maternal and fetal veno-arterial (VA) differences were in the same direction in 'acute' and in 'chronic' conditions for both lactate and glucose and of the same magnitude for lactate. For glucose, a good relationship was observed between umbilical VA differences and maternal arterial concentrations for all 'acute' and 'chronic' values. Thus no fundamental differences appear in the results obtained in 'acute' or during 'chronic' conditions. The applicability of such animal results to the human and the use of acute conditions to study fetal nutrition in the human are discussed.

Animals↗