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Biomedical subjects

A Salamon

Publications and source records attributed to A Salamon.

At least 19 recordsLinked to original sources

[Abdominal injuries in polytraumatised patients].

Authors have observed in 1978-1984 in 87 of 214 polytrauma cases injuries of the abdominal organs. The data concerning children in whom the high ratio of injuries of the abdominal organs and the low mortality are conspicuous are shown separately. The necessity of urgent diagnosis to which especially the abdominal irrigation has given great help is stressed. After a review of the literature and a control of their own material the problem is considered as actual, as in polytraumas the abdominal injuries are frequent, the valuation of the abdomen in the patient, generally in shock or unconscious is problematic, the many times simultaneous therapy of the abdominal and joined injuries is difficult, the mortality high.

Abdominal Injuries

[Incidence of fractures of the proximal femur and the distal end of the forearm (results of a Vas County survey compared to international data)].

Authors analysing the one year material of injured in one county, state the age and sex specific incidence in the two types of fractures. Compared with other European data they found difference in male/female distribution: the values concerning women are substantially lower in the county Vas, those of men are on the other side equal. To clear the difference and the tendency further examinations are thought to be necessary, especially regarding the increasing importance of femoral fractures of the hip region in public health and national economy.

Europe

[Classification of polytraumatized patients, experience with the ISS system].

Authors assessed the process of healing of 161 polytraumatized patients from 1976- to 1987, treated intersively, using the ISS system. Mortality was 27 per cent. Independently from the ISS system the concomittant shock foretold invariably a bad prognosis, although this was also joined generally to a big point number. The ISS system is simple and characterized the degree of the injury well. Through it, it will be possible to measure the gravity of the injury, to estimate statistically the prognosis and to compare the different materials. The number of points in the ISS system shows a good correlation with the survival (death) and the length of the intensive treatment. No patient was lost below 28 points whereas over 49 only 2 have survived. The point value may give information only up to the level of statistical probability concerning the prognosis (or the activity of the treatment) of the single patients. Because of its simplicity, its wide spreading and good practical use the general introduction of the ISS point system, as basic system, is thought to be advisable. For a more accurate judging a further making better and completing of the system (age, conjoined diseases, factors influencing each other mutually) further of the use, if necessary, of the scores applied in accident surgery and intensive therapy seems to be suggested.

Critical Care

Assessment of the intracardiac left to right shunts with a single scintillation probe.

In order to assess the accuracy of pulmonary time-activity curves obtained at bedside with a single scintillation probe and Technetium-99m-labelled erythrocytes, pulmonary to systemic flow ratio (Qp:Qs) was calculated for radionuclide and hemodynamic investigations in 104 patients with suspected intracardiac left to right shunts. Cardiac catheterization confirmed the presence of shunts in 76 patients. Pulmonary time-activity curve was 100% sensitive, 88% specific, and 96% accurate in detecting the shunt. Correlation between the radionuclide and hemodynamic Qp:Qs was excellent (r = 0.93). Results were classified in four quantitative categories according to the Qp:Qs values. In 76 patients (73%) radionuclide and hemodynamic data fell in the same category. We conclude that radionuclide pulmonary time-activity curves generated with a scintillation probe is a reliable method in quantitative assessment of intracardiac left to right shunts.

Adolescent

Independent evaluation of a multidisciplinary rehabilitation program for chronic low back pain.

Severe chronic low back pain was diagnosed in 236 patients by one physician and they were referred to the University of Miami Comprehensive Pain and Rehabilitation Center (UMCPRC) over a 5-year period for an intensive 4-week inpatient treatment program. Of these 143 (61%) were able to be contacted by telephone and given a structured interview designed for the study. The average time elapsed at follow-up from referral for all patients was 22.5 months. Outcome was measured in the following terms: current levels of pain, percent decrease in pain, subsequent health care utilization, activities of daily living, and attitudes toward treatment. After completion of the interview, the McGill Pain Questionnaire and the Oswestry Low Back Pain Disability Questionnaire were sent to the patients. The patients fell into five groupings: Group 1--participants in the UMCPRC program (n = 39); Group 2--those whose participation was not approved by insurance (n = 30); Group 3--those who declined participation (n = 46); Group 4--participants in other programs (n = 14); Group 5--dropouts (n = 14). The five groups were not meaningfully different with regard to prereferral demographics. Interestingly, Group 1 patients exhibited significantly greater prereferral pain and unemployment levels. Despite this, at follow-up significantly more Group 1 members were employed and they exhibited a greater percent decrease in pain as compared to the nonparticipant groups. Returned McGill and Oswestry Questionnaires mirrored these findings. Group 1 members also demonstrated significantly lower rates of subsequent health care utilization, i.e., physician visits, hospitalizations, and surgery than the nonparticipant groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult

[Immunohistochemical and immunologic changes in aponeurosis in Dupuytren's disease].

Authors examined the aponeurosis of 23 patients with Dupuytren's contracture and of 5, formerly healthy persons, who died in consequence of accidents. It was found that the IgA and IgM content of the palmar aponeurosis is significantly elevated in Dupuytren's disease. The distribution of the immunglobulin containing cells and the fibronection localisation of the aponeurosis was also examined. On the basis of their examinations they think that the autoimmun mechanism may have a role in the development of Dupuytren's disease.

Dupuytren Contracture

[Problems of the two-stage restoration of flexor tendon injuries. I. Current results. Biological and functional factors affecting healing].

After describing the morphological and biological relations in the intact human flexor tendon and tendon sheat unit authors deal in details with the severe injuries of the flexor tendons inside the tendon sheat, having a bad prognosis. The results of the previous experimental investigations, and among them their own results, are reviewed. The success of the two-phase tendon transplantations in this kind of injury is determined, according to their opinion, beside the known clinically related factors, by biological and functional factors. Further examination of the complicated reparative processes with the use of modern methods of investigation is planned. The present work is ment for introduction of these experiments.

Hand Injuries

[Problems of the two-stage restoration of flexor tendon injuries. II. Light- and scanning electron microscopy studies of flexor tendon sheaths from hens and from humans].

Authors examined the normal flexor tendon/tendon sheat unit of the toes of the hen and in the zone Verdan 2 of the human hand with light and scanning electron microscope. The fine structure of the synovial membrane was studied with special care. It was found, in accordance with some previous literary data, that the morphology of the hen's and human tenosynovium resemble to each other. The structures of the parietal visceral synovial membranes are described and compared, and the mechanism of the secretion of the synovial fluid is discussed. The results of the present investigations may serve, over the description of the normal anatomical relations, as a comparison to other experiments of two-phase tendon transplantations with the formation of pseudo tendon sheats and also for clinical practice.

Animals

[Biological and functional factors in 2-stage flexor tendon reconstruction].

After a review of the morphological and biological relationship of the intact human flexor tendon-sheath unit, the authors discuss injuries of the flexor tendon. They summarize research to date, including their own results. In their opinion, the success of two-stage tendon grafting used in the treatment of such injuries, apart from the known clinical factors, also depends on biological and functional factors.

Finger Injuries

[BCG osteitis].

Explore the source record for details and available documents.

BCG Vaccine

Immunopathological study on palmar aponeurosis in Dupuytren's disease.

The authors examined the immunological and immunohistochemical alterations of palmar aponeurosis in Dupuytren's contracture. In the IgG-content no difference were found between the intact and diseased aponeurosis. The mean of IgA content was 2 fold, the IgM content 3 fold higher in Dupuytren's aponeurosis than in normal ones. The immunoglobulin containing cells localised around the Dupuytren's nodules and in fibrotic, but not nodular parts of aponeurosis. Extracellular immunoglobulin deposits were not found.

Adult

Fine structural alterations of the palmar aponeurosis in Dupuytren's contracture. A combined scanning and transmission electronmicroscopic examination.

The authors examined the fine structural alterations of palmar aponeurosis in Dupuytren's contracture. Two types of the fibroblasts can be identified: classic fibroblasts and myofibroblasts. In the Dupuytren's tissue one fourth of all non-inflammatory cells were regarded as myofibroblasts. In the Dupuytren's aponeurosis the orientation of the thin and thick collagen fibers varied. The Paccini corpuscles were hypertrophised and around them compact collagen tissue was increased.

Adipose Tissue

Failure of injection of rat placental lactogen to inhibit prolactin in vivo.

In an attempt to demonstrate a negative feedback of rat placental lactogen (rPL) on prolactin secretion, pregnant rats were hysterectomized and injected intraperitoneally with placental extracts. Hysterectomy alone prolonged the incidence of nocturnal prolactin surges and injection of placental extracts did not alter this response. However, the absence of rPL in the serum following the injections indicated a primary reason why no inhibition was seen. Only when rPL was given intravenously was there detectable amounts found in the blood. The slow disappearance of rPL from the circulation following hysterectomy in Day 11 pregnant rats suggests that the lack of rPL in the blood following ip injection of placental extracts is not due to rapid clearance of rPL from blood. The failure to show a negative feedback of rPL on prolactin in vivo may be due primarily to the lack of appearance of rPL in the circulation following an ip injection of placental extracts.

Animals