Letter: Racial differences in leucoyte count.
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Biomedical subjects
Publications and source records attributed to A Rougemont.
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A coprological examination was performed among 410 adults living in two rural traditional villages of the Bamako region (Mali Republic). The results are compatible with those of several reports coming from other areas. A remark is done about Ascaridiasis which seems to be rare in rural communities of tropical Africa.
The neurologic examination of 90 leprosy subjects shows the importance of nerve enlargement and associated sensorimotor deficiencies. The association of various clinical signs, the ones in contrast to the others and the influence of the history of the illness are taken in consideration. Finally these results are compared with some previous works.
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An haematological, biological, parasitological and immunological study about anaemia of pregnancy was carried out in two rural village of Mali Republic, where P. flaciparum malaria is hyper-endemic. The 25 pregnant women found in the villages were compared with 23 controls. One could observe that anaemia more often normochromic and regenerative usually appears during the second trimestre of pregnancy. Only a few cases with haemaglobin levels below 8 g. % are hypochromic. Serum transferrin levels were slightly higher among pregnant. None among 31 bone marrows examined showed megaloblastic changes. Haptoglobin levels below 10 mg. % were observed in 3/4 of the pregnant women versus 1/4 in controls. Like some others, this study confirms the primary responsability of malaria haemolysis in the aetiology of anaemia of pregnancy and the interest of systematic chemoprophylaxis, at least from the third month of pregnancy. Vitamin and iron therapy is to consider therafter in hyper-endemic areas of P. falciparum malaria when nutritional problems are not predominant.
Between 1973 and 1976, 96 confirmed hospital cases of imported malaria occurred in Marseille. The collected epidemiological data indicate the recent increase of the annual incidence and an equal number of cases in immigrants and in people returning from the tropics. Among them, tourists, servicemen and merchant seamen are the groups most at risk. A high proportion of infections are with P. falciparum, mainly from Africa, Malagasy and Comoros. The diagnosis is only confirmed on an average of 6 days after the first medical advice and 2 patients died from falciparum infections. Travellers to tropical countries are often careless about taking prophylactic drugs and the danger of imported malaria should be emphasized.
Recent findings in Ivory Coast provide an opportunity to review possible factors influencing epidemiological differencies between forest and savanna patterns of onchocerciasis. Environmental factors, host factors, entomological and parasitological factors are taken into consideration. This provides evidence of two strains of parasite, associated with differences in pathogenicity, in biochemical structure, and with different species of the vector complex S. damnosum. The distribution of the severe pattern of the disease covers the area where the savanna vectors S. damnosum s.s. and S. sirbanum prevail, and extends as far as the southern limit of their range. In this respect, the terminology now in use appears to be justified by the geographical extent of the different patterns of the disease.
The authors point out the use of P. falciparum antigens from man in the Malaria IFA test. In Malaria areas it is very easy to find them and although they are "coated" by antibodies they are quite valuable in significant titers. The use of P. falciparum from man is therefore very interesting for Malaria diagnosis in non endemic areas and very useful for Malaria surveys in endemic areas.
Switzerland's first Master degree course in public health was launched in the autumn of 1990 at the Geneva University School of Medicine. It is a 3 year, part-time course, which is learner-centred and community-oriented. The aim of the course is to prepare students to use a multi-disciplinary approach to plan, implement and evaluate activities intended to solve public health problems. Throughout the course, studies plan, implement and evaluate projects concerning health problems they have encountered in their work as health professionals. The curriculum includes individual and group work, discussions and seminars with teachers and students, and brainstorming sessions with specially trained facilitators. The students can thus identify and fulfil individual educational objectives while working on community-related health projects. Priority health needs of individuals and communities are thus the pivotal points of the novel approach to public health training.