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Biomedical subjects

A Roe

Publications and source records attributed to A Roe.

11 recordsLinked to original sources

Specification of retinogeniculate X and Y axon arbors in cats: fundamental differences in developmental programs.

Monocular enucleation at E36, followed by intracellular labeling of single, physiologically identified X and Y axons, demonstrates fundamental differences in their termination patterns within the lateral geniculate nucleus (LGN). X axons have arbors that appear normal in their dorsoventral extent, though some are located in inappropriate regions of the LGN. Y axons have arbors that are either abnormally tall, spanning the entire extent of the LGN, or of normal height but located in inappropriate regions of the LGN. These termination patterns resemble patterns seen after monocular enucleation at E44, and reinforce the conclusion that X and Y axons differ fundamentally in the cues that constrain the dorsoventral extents of their arbors.

Animals↗

A comparative study of two methods of controlled mobilization of flexor tendon repairs in zone 2.

This prospective study compares subjects following primary repair of flexor tendons in zone 2 using either controlled active motion or a modified Kleinert regime. A matched pairs design was employed, subjects being matched for gender, age and injury characteristics. Twenty-six pairs of subjects with 92 tendon injuries in 52 digits were assessed 12 weeks postoperatively in respect of range of motion and dehiscence. Outcomes were defined using the Strickland criteria. No statistically significant differences in respect of range of motion were demonstrated between the groups. Incidence of rupture, however, was significantly less in the modified Kleinert group (7.7%) than in the controlled active motion group (46%).

Adult↗

Rectus sheath haematoma mimicking splenic enlargement.

Rectus sheath haematoma is uncommon and frequently misdiagnosed. In this paper an incorrect diagnosis of splenic enlargement was made. Ultrasound and computerized tomography revealed a large rectus sheath haematoma.

Aged↗

Anal sensation and the continence mechanism.

Thermal sensation is thought to be important in sensory discrimination between different substances. The aim of this study was to determine the thermal sensitivity in the anal canal in continent patients with hemorrhoids (N = 20), a group that has been reported to have a sensory deficit, and to compare the results with control subjects (N = 40) and patients with idiopathic fecal incontinence (IFI) (N = 22). Anal manometry was performed and sensation to mucosal electrostimulation and temperature change in the lower, middle, and upper zones of the anal canal assessed. Thermal sensation was impaired in the hemorrhoid group as compared with controls, but not to the same degree as in IFI (e.g., median thermal sensitivity in mid anal canal, control 0.9 degrees C, hemorrhoid 1.2 degrees C, IFI 2.0 degrees C, P less than .05 and less than .001, respectively). The correlation between the two tests of sensation was 0.54 (P less than .001) and the reproducibility of thermal sensory thresholds was 0.82 (P less than .001). In conclusion, patients with hemorrhoids have a mild anal sensory deficit, but continence in this group is likely to be augmented by other factors.

Adult↗

Differential functioning on the Illingworth by home- vs institution-reared 3-month-old infants.

The performance on the Illingworth of 32 3-mo.-old home-reared Greek infants was compared to that of 22 infants reared in a modern institution. Home-reared infants were superior to institutional infants in every aspect of development except on Manipulations (fine motor coordination). It is speculated that the superiority of the home infants is attributed to the quality of the mother/caretaker-infant relationship.

Achievement↗

Obstructed defaecation.

Obstructed defaecation is a common anorectal symptom frequently but not invariably associated with perineal descent. Associated excessive straining at stool leads to external sphincter neuropathy, but this per se does not cause incontinence. Where simple measures are unsuccessful evacuation proctography should elucidate the cause of the obstructive constipation and allow rational treatment.

Anal Canal↗

Infant Gesell scores vs. cognitive skills at age 12 years.

In an earlier study, it was found that infant performance on the Gesell correlated better with performance on nonverbal than verbal cognitive skills up to the age of 5 years. Recently, the same 26 male middle-class Ss, now 12 years old, were retested with the WISC-R, WRAT, and PPVT. Performance on the Gesell was found to relate significantly to WISC-R Performance IQ and to a lesser extent to PPVT IQ, but did not relate to WISC-R Verbal IQ nor to performance on the WRAT. The results suggest that the Gesell has a better predictive validity for nonverbal than verbal cognitive skills.

Child↗

Patterns in productivity of scientists.

Bibliographies of 53 eminent research scientists in different fields are analyzed in terms of total publications, type of publication, coauthorship, and mean number of publications per year. For the physical and biological scientists, comparisons are made with the publication records of 153 eminent 19th-century scientists.

Anthropology↗