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Biomedical subjects

A Ridley

Publications and source records attributed to A Ridley.

41 records · Page 3Linked to original sources
PubMedDate not supplied

An immunofluorescence study of the passive arthus reaction in rat sciatic nerve.

The Arthus reaction, passively induced in rat sciatic nerve by local injection of antibody and intravenous injection of antigen, was studied by immunofluorescence, using fluorescein and tetramethylrhodamine isothiocyanate. The reaction in nerve is similar to that occurring in skin. Antigen-antibody complexes formed at the site of the reaction activate complement and attract large numbers of polymorphonuclear leucocytes which then ingest the immune complexes. The significance of the Arthus reaction in relation to diseases of the peripheral nervous system is mentioned.

Animals↗
PubMedDate not supplied

The carry-over of Campylobacter isolates between sequential poultry flocks.

The carry-over of Campylobacter strains from one flock to a subsequent flock in the same broiler house has been studied using molecular epidemiological techniques. In all, 524 Campylobacter strains, isolated from two sequential broiler flocks from 60 broiler houses, were typed by restriction fragment polymorphism of the polymerase chain reaction (PCR) product of the flaA and flaB genes (fla typing). Selected strains were also typed using pulsed field gel electrophoresis (PFGE). By fla typing, 15 (21%) of the 60 houses with Campylobacter-positive sequential flocks had identical genotypes. In 10 (16% overall) of these houses the strains were also identical by PFGE. The difference in PFGE patterns in the strains from the three remaining houses may be indicative of genetic instability. Overall, these results suggest that carry-over from one flock to a subsequent flock in the same house is a relatively infrequent event and, therefore, that routine broiler house cleansing and/or disinfection is largely adequate to eliminate Campylobacter contamination. An alternative explanation of the low level carry-over is a persistent source or reservoir, external to the environment of the broiler houses.

Animal Husbandry↗