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Biomedical subjects

A Ridley

Publications and source records attributed to A Ridley.

At least 37 records · Page 2Linked to original sources

Treatment of the Guillain-Barré syndrome by plasma exchange.

Twelve consecutive patients with Guillain-Barré syndrome were treated with plasma exchange. Examination two weeks after treatment was commenced showed that three had not improved. Five showed only a minimal improvement, which was considered to be compatible with the natural history of the disease. The remaining four patients showed a more substantial improvement which could have been related to the plasma exchange.

Adult↗

Lymphocyte-mediated cytotoxicity against gliomas.

The effects of peripheral blood lymphocytes from patients with glioma on glioma cells grown in culture was studied using an in vitro microcytotoxicity test. Lymphocytes from 12 of the 20 patients studied showed significant cytotoxic activity against their own tumour cells. Four of them reacted against heterologous glioma cells and 4 also showed some reactivity against foetal brain cells. An attempt to correlate in vitro cytotoxicity with the degree of lymphocytic infiltration of the tumour suggested an association, but the number of cases examined was too small to achieve statistical significance.

Adult↗

Cerebellar ectopia presenting in adult life.

Three cases of cerebellar ectopia first producing symptoms in adult life are reported. This potentially remediable anomaly may not be suspected in adults, in whom associated congenital bony abnormalities of the skull and cervical spine are often absent. In these cases diagnosis depends on radiological contrast studies; in particular it is important to examine the cervical canal in the prone and supine positions.

Adolescent↗