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Biomedical subjects

A Ramos

Publications and source records attributed to A Ramos.

At least 271 records · Page 15Linked to original sources

Renal involvement in leprosy.

Renal involvement in Hansen's disease was evaluated in 94 Portuguese patients, average age and duration of disease of 47.6 and 6.8 years respectively. Sixty-seven were studied retrospectively and 27 prospectively; renal biopsy was obtained in 4, fat-tissue needle aspiration for amyloidosis in 20, and tubular function was tested in ten. Mild proteinuria and/or haematuria was found in 33 patients, the severity increasing during erythema nodosum leprosum reactions, but without overt nephritic or nephrotic syndrome. Two patients had renal amyloidosis on biopsy and two more were confirmed by fat biopsy, a 10.5% incidence in those studied prospectively; all but one were of the lepromatous type, with frequent bouts of erythema nodosum leprosum. The two other renal biopsies showed mesangial glomerulonephritis, and one unexplained acute tubular necrosis; none had immune deposits by immunofluorescence. Proximal acidification was always normal, distal acidification tested by bicarbonate infusion was abnormal in one of nine patients, and six of nine patients had concentration defects. Leprosy causes frequent urinary sediment changes and concentration defects, usually without clinical expression; proteinuria and/or glomerular involvement is mainly due to amyloidosis.

Adolescent↗

[Congenital cardiopathy in a series of 53,578 children born in Oviedo (1976-1985)].

A diagnosis of congenital heart disease was carried out in the 5.2/1,000 of 53,578 live neonates who were born in the Hospital "Nuestra Señora de Covadonga" from 1-1-1976 to 12-31-1985. A relatively high and low incidences of ventricular and atrial septal defects were respectively found. The 69.1% of heart diseases were identified in the first month of life.

Adolescent↗

Cohort study of intestinal infection with campylobacter in Mexican children.

A cohort of 179 children under 5 years of age from a low-income urban community was followed up for a year to determine the incidence of symptom-producing and of diarrhoea-free campylobacter intestinal infections, and thus their illness-to-infection ratio. 66% of all children had at least one campylobacter infection, one-third of these being associated with diarrhoea. The annual incidence of all campylobacter infections was 2.1 episodes per child. The incidence was inversely related to age (r = -0.78 p less than 0.02). The illness-to-infection ratio, which in infants younger than 6 months was 1:2, was negatively associated with age (r = -0.7, p less than 0.02). Only symptom-producing infections occurring early in life seemed to protect against subsequent infections.

Age Factors↗

EEG maturation on children with different economic and psychosocial characteristics.

It has been shown that EEG maturation can be described in terms of regression equations on age of broad band EEG frequency parameters. In the present paper six groups of children with different economic and psychosocial characteristics of three countries were studied. Regression equations on age of the EEG relative power (expressed in percentages of the total EEG activity) in the delta, theta, alpha and beta bands in 8 bipolar derivations were computed in each group of children and the slopes compared with those previously published by John et al. (1980). Those children who grew up with adequate nutritional, sanitary and cultural environmental conditions showed the same slopes as U.S. and Swedish children selected with strict criteria of normality. Children nourished in poor socioeconomic and sanitary environments and who frequently had pathological personal antecedents with risk factors associated with brain damage showed either a slow maturation of the EEG characterized by smaller slopes of theta relative power or a great variance of EEG parameters and no relation of these parameters to age.

Child↗

Lipids, lipoproteins, and apoproteins in serum during infection.

We studied the alterations in the concentrations of total cholesterol, high-density lipoprotein cholesterol, triglycerides, and apoproteins A and B in serum of 54 patients hospitalized for various reasons, who developed sepsis during their stay. Forty of these patients required intensive care, 14 did not. Another group of patients with the same underlying pathological conditions was used as a control. We found the following: Sepsis causes the concentrations of total cholesterol, high-density lipoprotein cholesterol, and apoproteins A and B in serum to decrease, whereas triglycerides increase. However, these changes are not related to the infectious agent, the underlying illness, or the clinical situation of the patients. The return of serum lipids to more normal concentrations parallels the recovery from sepsis. The positive correlation between the drastically decreased concentrations of high-density lipoprotein cholesterol and the severe hypoalbuminemia in these patients suggests a common pathway for these two abnormalities.

Adolescent↗

Efficacy of flecainide in the management of ventricular arrhythmias: comparative study with amiodarone.

The effects on ventricular arrhythmias of a new class IA drug, flecainide, were compared with those of amiodarone in 10 patients with frequent, chronic, and stable ventricular ectopic beats (VEBs). The study consisted of an initial 1-week, placebo-controlled, baseline period followed by two 12-day, randomized, crossover, double-blind treatment periods with incremental dosage and 1 month of placebo between drug periods. Frequent VEBs, which were present in all 10 patients during both placebo control periods (30 or more VEBs/hour every hour, during 24-hour Holter monitoring), were markedly suppressed (reduction greater than 80%) in nine patients with both drugs (p less than 0.01). There was almost total abolition of the VEBs in six patients with flecainide, and the satisfactory results with a minimal dose in three demonstrate its fast onset of action. Side effects from either agent were infrequent and no discontinuation was necessary. We conclude from our study that flecainide is a highly effective antiarrhythmic agent.

Adult↗

Nephrolithiasis in premature infants.

The clinical records of ten premature infants with nephrolithiasis were reviewed. The probable mechanism of stone formation was hypercalciuria due to furosemide therapy (nine patients) and congenital hyperparathyroidism (one patient). The relatively high rates of urinary excretion of calcium from immature kidneys predisposed these neonates to the development of calcium stones. Renal calculi in neonates are complications of distinct, treatable conditions, and premature babies receiving furosemide treatment should be screened by ultrasonography for renal calcifications.

Female↗

Osseous lipoma: CT appearance.

Characteristic radiographic and computed-tomographic (CT) features of seven cases of osseous lipoma are reported: six with medullary and one with parosteal locations. Radiological diagnosis of this lesion is discussed, with emphasis on potential pitfalls in interpretation of CT scans. Although the presence of fat-equivalent density on scans is highly suggestive of osseous lipoma, comparable attenuation is documented in cases of chronic osteomyelitis and postnecrotic subchondral excavation.

Acetabulum↗