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Biomedical subjects

A Primavera

Publications and source records attributed to A Primavera.

80 records · Page 5Linked to original sources
PubMedDate not supplied

Gastrointestinal complication of high-dose corticosteroid therapy in acute cerebrovascular patients.

Corticosteroids are commonly used in the treatment of stroke, although their clinical effectiveness has not been established. Side effects, especially gastrointestinal complications, occur in patients with cerebral disease. A necroscopy study of 124 patients investigated the occurrence of gastrointestinal lesions in patients with acute stroke treated with high-dose of corticosteroids compared to untreated patients with stroke and to patients dying from non-vascular neurological diseases. A significant relationship between the use of steroids and gastrointestinal lesion in strokes is demonstrated.

Acute Disease↗
PubMedDate not supplied

Simple renal cysts in hypertensive patients: relation between cyst growing and anti-hypertensive therapy.

The study investigates relationship between simple renal cyst enlargement studied by ultrasonography and anti-hypertensive treatment. To this purpose we enrolled 42 patients with newly diagnosed hypertension affected by simple renal cysts. Fourteen were randomly assigned to treatment with ACE-Inhibitors (group 1), twelve to diuretics (group 2) and sixteen to Ca-Antagonists (group 3). Patient performed a basal ultrasonography to evaluate basal cyst dimension before starting anti-hypertensive treatment. Following 12 months of the anti-hypertensive regimen, a new echograph was performed to evaluate changes in cyst size. A control group consisting of 15 patients with normal blood pressure and simple renal cysts was enrolled (group 0). An enlargement of cysts was detected in all patients. However, the enlargement observed in patients treated by Ca-Antagonists was significantly greater than that observed in the other groups (p<0.05). Our study supports the hypothesis that Ca-Antagonists may favor cyst enlargement by enhancing cyclic AMP production. In fact, cAMP and cAMP agonists stimulate fluid secretion by lining cells of the cyst wall, inducing cyst enlargement.

Aged↗
PubMedDate not supplied

[Triphasic waves in dementia syndromes].

Seventy-one EEGs (0.49%) of 53 patients, out of 14,458 recordings, contained triphasic waves: twenty-nine were patients with metabolic encephalopathies and 24 were demented patients (16 of these had a presumptive diagnosis of Alzheimer's disease and the other eight of mult-infarct dementia). Demented subjects with metabolic disorders are included in the metabolic encephalopathies group. In all of the cases of Alzheimer's disease, triphasic waves were atypical: in 14 they occurred singly or in short bursts, in 10 they had occipital predominance and in 2 they were bilateral but asymmetrical. In 5 cases, triphasic waves were associated with myoclonus and in 2 of them they occurred in long runs with a pseudo-periodic pattern. In these cases the distinction from Creutzfeldt-Jakob disease was based on neuropathologic findings.

Aged↗
PubMedDate not supplied

Amyloid neuropathy in light chain multiple myeloma.

We describe a 73-year-old man with peripheral neuropathy and light chain lambda-type myeloma. A sural nerve biopsy showed the typical neuropathological picture of amyloid neuropathy. With the present case we first demonstrate amyloid deposits in peripheral nerves during light chain multiple myeloma and stress the importance of amyloidosis in the development of peripheral neuropathy.

Aged↗
PubMedDate not supplied

[Hemispheric cerebrovascular lesions with secondary brain stem involvement. Anatomo-clinical study].

The authors studied incidence, nature and place of vascular injuries of brainstem secondary to acute hemispheric vascular injuries. In a large number of 363 patients deceased and submitted to autopsy, incidence was 10.2%, higher in haemorrhagic primitive injuries (13.4%) in comparison with ischemic ones (4.9%). The nature of brainstem secondary injuries appears to be above all of haemorrhagic type and pons the favourite place. Such injuries are determined not only by compression but also by distorsion of brainstem.

Acute Disease↗