Abortion procedure.
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Abortifacient Agents, Nonsteroidal↗
Biomedical subjects
A P Schneider
Publications and source records attributed to A P Schneider.
Human parvovirus infection.
Fifth disease (erythema infectiosum) has recently been linked to human parvovirus (HPV) infection. HPV is also capable of causing aplastic anemia, arthritis and perinatal complications, including hydrops fetalis and spontaneous abortion. Clinically suspected cases of HPV infection can now be confirmed serologically. IgM antibodies peak early in the course of infection and are usually undetectable by two months. New procedures, including HPV-specific DNA probes, are being used to confirm in utero infections.
Anemia, Aplastic↗
Human parvovirus infection and seronegative-like arthritis in adults.
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Adult↗
Risk factor for ovarian cancer.
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Breast Feeding↗
Breast milk jaundice in the newborn. A real entity.
I have reviewed clinical trials that provide data relative to the comparative rates, means, or odds ratio of jaundiced normal breast-fed newborns vs jaundiced normal formula-fed newborns. A pooled analysis of 12 studies revealed moderate jaundice (serum bilirubin level, greater than or equal to 12 mg/dL) in 514 of 3,997 breast-fed vs 172 of 4,255 formula-fed newborns. An analysis of six of these 12 studies demonstrated severe jaundice (serum bilirubin level, greater than or equal to 15 mg/dL) in 54 of 2,655 breast-fed vs ten of 3,002 formula-fed newborns. Eleven of 13 studies found breast-fed newborns to have a higher mean serum bilirubin level. One study of 12,023 newborns found a significant (odds ratio, 1.80) relationship between breast-feeding and jaundice of the newborn. In conclusion, breast-feeding is one common cause of jaundice in normal newborns in the first week of life and beyond.
Breast Feeding↗
The coughing child. A primary care perspective.
Cough in children, even in infants under 1 year of age, is a frequent problem in clinical practice. Many causes are possible and should be considered, but only a few are likely. In primary care, appropriate evaluation is based on skillful history taking. In an ostensibly healthy child or infant with recurrent episodes of nighttime cough preceded by an upper respiratory infection, asthma should be strongly considered. This is especially important when there is a positive family history of asthma.
Age Factors↗
Induction of hemoglobin accumulation in human K562 cells by hemin is reversible.
Twenty micromolar hemin causes no change in the rate of division of K562 cells but results in accumulation of 11 to 14 picograms of embryonic and fetal hemoglobins per cell. This effect is reversible, and hemoglobin induction in response to hemin, and loss of hemoglobin upon removal of hemin, can be cyclically repeated. The cells can be indefinitely subcultured in the presence of the inducer. Thus, the control of hemoglobin levels in K562 cells does not depend on irreversible differentiation.
Cell Differentiation↗
In-hospital cardiopulmonary resuscitation: a 30-year review.
BACKGROUND: We performed a meta-analysis to: (1) assess the disputed issue of in-hospital cardiopulmonary resuscitation (CPR) success rates among elderly patients, (2) investigate the possibility of a declining CPR success rate between 1960 and 1990, (3) provide an overview estimate of CPR effectiveness in specific patient groups, and (4) assess CPR risks. METHODS: Ninety-eight reports providing in-hospital CPR survival-to-discharge rates were included in this overview. These reports were identified from MEDLINE searches, previous reviews, and reference citations. RESULTS: A pooled analysis revealed that 2994 (15 percent) of 19,955 patients were successfully resuscitated (survival to discharge). The rate of successful CPR has not changed in 30 years (r = -0.14, P > 0.05), but there has been a steady decline in the optimism regarding its value (r = -0.29, P < 0.01). Patients younger than 70 years of age had a success rate of 16.2 percent (odds ratio = 1.36; 95 percent confidence interval, 1.20 to 1.53) versus 12.4 percent for patients older than 70 years (P < 0.001). Community hospitals had a higher CPR success rate than teaching hospitals (18.5 percent versus 13.6 percent, P < 0.001). Although 72.9 percent of the post-CPR deaths were within 72 hours, prolonged in hospital survival in a vegetative state did occur; 1.6 percent of successfully resuscitated patients had a permanent neurological impairment. CONCLUSION: The increasing pessimism about the value of CPR, specifically, its futility in the elderly patient, is not supported by this review. The results of this meta-analysis should assist both the physician and the patient in determining the probable outcome of CPR.
Age Factors↗