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Biomedical subjects

A Oehling

Publications and source records attributed to A Oehling.

At least 37 records · Page 2Linked to original sources

Lepromatous leprosy and contact dermatitis.

The rare association of lepromatous leprosy and allergic contact dermatitis due to chromium in cement was confirmed clinically and biologically in a male patient. The apparent lack of influence of lepromatous leprosy on the development and maintenance of this dermatitis dependent upon cell-mediated immune mechanisms is discussed.

Adult↗

[Standardization of in-vitro methods for diagnosing allergic disorders].

The various "in vitro" techniques were studied and the conclusion was reached that the hemagglutination and complement fixation tests were the most suitable for diagnosis. Sera were selected from 377 patients with very positive intracutaneous reactions to the antigens in question, the distribution being as follows: 110 sera positive to milk, 114 sera positive to eggs, 95 sera with a very marked intracutaneous reaction with gramineous pollen, and 58 with house dust. By means of the hemagglutionation technique of Boyden and the complement fixation test of Kolmer with these antigens, it was determined that the diagnostic reliability for food substances was 94,4% in the sera with positive anamnesis. For milk, there was 100% reliability in bronchial asthma and atopic dermatitis. With respect to pollen, hemagglutination gave 100% reliability in patients with positive anamnesis. The percentage with complement fixation was somewhat lower. Comparing the diagnostic reliability with hemagglutination, house dust gave an arithmetic average of 82,6% in positive anamnesis. With these antigens, hemagglutination by Boyden's technique appears the most suitable method.

Animals↗

Aerosol chemotherapy in bronchopulmonary candidiasis.

One of the most frequent complications encountered in non-specific respiratory pathology of recent years is overinfection by Candida albicans. An important contributive factor is the recent massive antibiotherapy, above all with tetracyclines, favouring this overinfection. Since at present the treatment of bronchopulmonary processes is difficult owing to the lack of an effective oral or parenteral therapy, a study was carried out of 33 patients treated with nystatin and amphotericin B in aerosol form, with 3-4 sessions of treatment per day, during a minimum of 10 days. At each session either 50,000 U of nystatin or 5 mg of amphotericin B were administered. The results obtained showed that after treatment, C. albicans was no longer present in the sputum of 84% of cases treated. In view of these results it is considered that - at present - the two most suitable substances for the treatment of pulmonary candidiases are nystatin and amphotericin B in aerosol form.

Adolescent↗