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Biomedical subjects

A Nowakowski

Publications and source records attributed to A Nowakowski.

At least 55 records · Page 3Linked to original sources
PubMed1982

Ultrastructural aspects of leukaemic cells in acute myeloblastic leukaemia.

Ultrastructural aspects of leukaemic cells in a case of myeloblastic leukaemia are described. Changes concerning of mitochondrial ultrastructure, but primarily the presence of vast numbers of fibrillar structures in the cytoplasm of the examined cells were observed. These structures were spreading through their gradual widening to cover almost the whole cell cytoplasm, damaging its organellae and internal architecture. The nature of the observed changes remains unknown.

Bone Marrow↗
PubMed1977

Nonrandom chromosome rearrangements in 27 cases of human myeloid leukemia.

The R-banding pattern of the chromosomes of 31 patients hospitalized in the Hematologic Clinic for myeloid leukemia were studied before chemotherapy. This analysis permitted identification of one unusual 3-chromosome rearrangement t(3;9;22) in addition to 25 classic forms of (22q-;9q+) translocation accompanied by the specific Ph' chromosome in chronic granulocytic leukemia patients, independent of the blastic course of the disease. During blastic crisis observed in 6 patients, extra 8 and 10 chromosomes, monosomy for chromosome 17, isochromosomes 17q, translocation (12q;13q), and additional Ph' were noted. The nonrandomness of these findings is determined from results published by other authors. Their significance for the cellular phenotype is presently unknown.

Chromosome Aberrations↗
PubMed1976

[Leukemic form of lymphosarcoma (clinical study of 7 cases].

Seven cases of leukaemic form of lymphosarcoma are presented. In all studied patients three characteristic signs were present: generalized lymphadenopathy, presence of lymphosarcoma cells in peripheral blood, spontaneous proliferation of white blood cells in short-term culture. Differential diagnostic difficulties with regard to chronic lymphatic leukaemia are stressed. It is thought that the sign of spontaneous proliferation may be used as a differential diagnostic criterion.

Adult↗