Search PubMed⌕ Search

Biomedical subjects

A Neuhold

Publications and source records attributed to A Neuhold.

86 records · Page 5Linked to original sources
PubMed1985

[The use of sonography in the diagnosis of pathological changes in the mouth floor and tongue region].

The application of real-time sonography in the area of the tongue and floor of the mouth is described. Its value is examined by a sonographic-surgical correlation of 40 examinations. In 38 cases, the sonographic findings correlated well with the clinical picture, as well as with the intraoperative and pathologic findings. Ultrasound seems to be a practicable imaging method, especially with malignant infiltration of the tongue.

Carcinoma, Squamous Cell↗
PubMed1985

[Sonographic, clinical and surgical correlations in the diagnosis and control of the course of tongue infiltrations].

With a high-resolution sonographic system, anatomical details in the area of the floor of the mouth and tongue are visualized. The value of sonography in the pretherapeutic assessment of suspicious palpation findings was investigated. 22 patients' tumors were examined during radiation, to document the course of therapy. 55 sonograms were evaluated and confirmed the excellent applicability of this procedure in the precise pretherapeutic determination of the size of the lesions and their relation to the surrounding structures. The tumors are readily detected even during radiotherapy.

Humans↗
PubMed1984

[Radiologic-endoscopic correlation in ulcerative colitis].

Double-contrast irrigoscopies (DCI) performed in 32 patients with confirmed ulcerative colitis are reviewed and correlated with colonoscopy. Whereas endoscopy proved more efficient in assessing superficial changes of the mucosa, DCI was found to be superior in the detection of deeper mucosal lesions and changes in the anatomic aspect of the colon wall. Moreover, DCI showed advantages in the evaluation of the entire colon including the coecum; examination of the coecum by endoscopy was achieved in 31% only of the scrutinised cases.

Colitis, Ulcerative↗
PubMed1984

[Fine relief of the stomach and diagnosis of gastritis. A radiologic-endoscopic-histologic comparative study].

To assess the sensitivity of radiology in diagnosis of gastritis within 2 hours endoscopy and biopsy of the stomach and double contrast barium meal were performed. The diagnosis was established of the morphologic picture of the areae gastricae, which were sufficient visible in 33 out of 50 cases (66%). In 7 patients radiologic findings were normal, 13 patients showed superficial gastritis, 10 patients had superficial gastritis with signs of atrophy and in 3 patients there was an erosive gastritis. In all 33 patients (100%) there was a complete correlation of radiologic and endoscopic findings, in 24 out of 33 cases (73%) even correlation between radiologic and histologic classification. These results are discussed and confrontated with literatures.

Adult↗
PubMed1983

[Tumor-like bursal calcifications due to uncontrollable hyperphosphatemia in chronic hemodialysis. Case report].

The most important factor that appears to be associated with soft-tissue calcifications in uremics is the increase of serum-phosphate levels, especially if the calcium-phosphate product exceeds the value of 75 (concentrations in mg/dl) [6]. In contrast to previous years tumoral paraarticular calcinosis is now rarely seen because much more attention has been paid to the prevention of hyperphosphatemia and because of pharmacological improvement of phosphate binding agents. Therefore, the level of serum phosphate in hemodialysed patients primarily depends on the patients adherence to the low phosphate diet and compliance with the phosphate binding therapy [4, 8]. We want to report of a patient on chronic intermittent hemodialysis who developed tremendous paraarticular soft tissue calcifications during a short period of time due to uncontrolled hyperphosphatemia despite correct intake of phosphate binding compounds.

Bursa, Synovial↗
PubMed1982

[The value of sonography in the follow-up of patients with transplanted kidneys].

42 cases with transplanted kidneys were examined by ultrasound. The results were compared critically with clinical and histological data. The ultrasound findings are identical with the other findings in 86%. Ultrasound therefore together with clinical laboratory and nuclear medical findings can in a very high percentage replace other high risk examinations like retrograde pyelography or angiography.

Acute Disease↗
PubMedDate not supplied

Quantification of regurgitant lesions by MRI.

We examined 46 patients with angiographically documented regurgitant lesions (26 patients with mitral regurgitation, 20 patients with aortic regurgitation) using an 0.5 Tesla magnet. In each patient a multislice-multiphase spinecho sequence in sagittal-coronal double angulated plane was performed to assess left and right ventricular volumes, ejection fraction and regurgitant fraction. Additionally a blood flow sensitive gradient echo technique was done to visualize direction and extension of the regurgitant jet. MRI data were compared with quantitative and qualitative assessment of regurgitation by angiography and echocardiography. Using the gradient echo technique MRI could demonstrate the regurgitant jet in all patients. A linear correlation for volume parameters by MRI and angio was found with best correlation for the left ventricular stroke volume (r = 0.82, p less than 0.0001). Furthermore MRI regurgitant fraction correlated with angiographically determined regurgitant fraction in patients with aortic regurgitation (r = 0.91, p less than 0.0001) and mitral regurgitation (r = 0.67, p less than 0.001), respectively. Semiquantitative assessment of regurgitation by gradient echo technique showed an agreement with angiographic grading by Sellers in 70% of mitral and 75% of aortic regurgitation, respectively. The comparison of MRI and color Doppler sonography showed only moderate correlation of r = 0.72 (p less than 0.01).

Aortic Valve Insufficiency↗
PubMedDate not supplied

Degenerative Achilles tendon disease: assessment by magnetic resonance and ultrasonography.

As Magnetic Resonance (MR) imaging and Ultrasound (US) allow the evaluation of soft-tissue structures not previously possible with other imaging techniques, a clinical study has been undertaken to determine the value of these two modalities in the detection of lesions in the Achilles tendon (AT), other than acute total rupture. Seven healthy subjects and 28 symptomatic patients with Achillodynia and/or signs of thickening of the AT were investigated with MR and US; all results were compared with the clinical features. Surgical findings were available in 14 patients. The patients were divided into three groups; those with tendon thickening, incomplete and complete chronic ruptures. Thickening of the AT was easily detected with both methods. MR was superior in the detection of incomplete tendon rupture and in the evaluation of various stages of chronic degenerative changes. We conclude that only if US remains unclear, an additional MR study should be performed and together with the clinical diagnosis indication for surgery can be made more efficient.

Achilles Tendon↗
PubMedDate not supplied

Assessment of mitral regurgitation by magnetic resonance imaging.

To evaluate the potential of magnetic resonance imaging (MRI) in detection and quantification of mitral regurgitation, 26 pts. with echocardiographically or angiographically documented mitral regurgitation were examined using a 0.5 Tesla superconducting magnet. In each patient a multislice-multiphase study in a sagittal-coronal double angulated projection (four-chamber view equivalent) was performed to assess left and right ventricular volumes, ejection fraction and regurgitant fraction. Additionally a blood flow sensitive cine-study (fast field echo: FFE) was done to visualize direction and area of regurgitant jet. MRI data were compared with quantitative and quantitative assessment of mitral regurgitation by angiography, 2D echocardiography, Doppler sonography and color flow mapping. Using the FFE mode MRI was able to detect the regurgitant jet as a typical signal loss within the left atrium in all patients. The ratio of regurgitant jet area/left atrium area as determined by MRI showed a correlation with a comparable ratio from color Doppler sonography of R = 0.87 (p less than 0.001). There was also good agreement in semiquantitative grading of mitral regurgitation between MRI and angiography (R = 0.77, p less than 0.001). The determination of left and right ventricular stroke volume allowed the calculation of the regurgitant fraction, which showed a correlation with invasively determined regurgitation fraction of R = 0.84 (p less than 0.001). These data provide additional information that MRI may be useful as a noninvasive technique to detect and quantify mitral regurgitation.

Adult↗
PubMedDate not supplied

Bone marrow edema of the hip: MR findings after core decompression.

Magnetic resonance imaging is an extremely sensitive technique for evaluation of bone marrow changes at an early stage of avascular necrosis (AVN) of the hip. We therefore examined 11 painful hips whose clinical symptoms led us to suspect idiopathic AVN. The radiographs of all of these either were normal or demonstrated a minimal decrease in radiodensity. Magnetic resonance demonstrated diffuse signal loss of the bone marrow at short TR/TE images of the femoral head in all hips, with various extensions in the head, neck, and intertrochanteric area. These regions turned iso- to hyperintense on long TR/TE images compatible with bone marrow edema (BME). Focal abnormalities characteristic for AVN were not seen in any of the cases. Radionuclide studies performed in six cases were positive. All patients underwent core decompression treatment. Hydrostatic bone marrow pressure measurement and intraosseous venography were positive in five cases when measured. Histology available in eight cases confirmed the presence of BME. Furthermore, the bone changes corresponded to those of early AVN. Follow-up examinations after core decompression with MR showed normal signal intensity in all cases. Magnetic resonance represents a viable diagnostic tool for BME and can monitor the therapeutic success of core decompression. Whether BME of the femoral head constitutes a distinct transient syndrome or represents an early form of AVN is controversial at present. Our findings support those who believe that BME may represent an initial stage of idiopathic AVN.

Adult↗
PubMedDate not supplied

Down syndrome: MR quantification of brain structures and comparison with normal control subjects.

For quantification of brain structures from MR scans, a novel, powerful stereologic tool known as Cavalieri's principle was applied. This tool enables an objective estimation of volume. The method was applied to detect differences in various brain structures between persons with Down syndrome and control subjects. On the basis of absolute values, smaller volumes for the whole brain, cerebral cortex, white matter, and cerebellum were seen in persons with Down syndrome. Similar results were observed when a normalization procedure, based on the volume of cranial cavity, was used. Stereologic determinations of the volumes of brain structures from MR images can reliably identify volume differences between persons with Down syndrome and control subjects.

Adult↗
PubMedDate not supplied

Long term follow-up of radiological signs of pulmonary hypertension in correlation with haemodynamic changes.

Patients with pulmonary hypertension of unknown cause show a typical radiological pattern with prominence of the pulmonary segment, increase in diameter of the right descending branch of the pulmonary artery and marked tapering of the peripheral vascular bed. The aim of this study was to evaluate if changes in radiological indices correlate with hemodynamic changes during long term follow-up, in 19 patients with pulmonary hypertension followed for a mean of 8.4 years. In 10 patients, an increase in pulmonary arterial pressure (Ppa) was measured, and in all further increase in the diameter of the right descending branch was seen. The prominence of the pulmonary segment increased in only six of the ten patients. In three patients, no change in Ppa and in the radiological signs was noted. But in four of six patients a decrease in Ppa was not followed by changes of the radiological signs. In conclusion, we could show that there is a good correlation between radiological signs of pulmonary hypertension and further increase of pulmonary arterial pressure in patients with pulmonary hypertension, whereas a decrease in pressure is not necessarily reflected by a decrease in the radiological signs.

Adolescent↗
PubMedDate not supplied

Morphometric analysis of the corpus callosum using MR: correlation of measurements with aging in healthy individuals.

PURPOSE: To analyze changes of the human corpus callosum and MR midsagittal brain structures during normal aging. METHODS: A morphometric evaluation strategy for quantification of these brain structures on MR scans was developed. This computerized measuring program did allow the acquisition of more than 100 one- and two-dimensional parameters. RESULTS: During normal aging, the anterior parts of the corpus callosum (genu and anterior parts of the trunk) were significantly decreased, suggesting alterations of frontal and temporal interhemispheric fiber systems. Further changes were seen in callosal thickness and callosal width of the anterior parts of the corpus callosum. The profile area of the telencephalon was significantly reduced during normal aging. The size of the mesencephalon showed age-specific changes. CONCLUSIONS: The proposed computer program proved to be a powerful and reliable tool to get objective and reproducible quantitative data of corpus callosum and midsagittal brain structures. Specific age changes were found in the corpus callosum, indicating alteration of the frontotemporal interhemispheric fiber systems.

Adult↗