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Biomedical subjects

A Neri

Publications and source records attributed to A Neri.

At least 289 records · Page 16Linked to original sources
PubMed1980

Multiple myeloma in husband and wife.

An instance of multiple myeloma (MM) in a married couple is discussed, since cases of MM in husband and wife have rarely been observed. The patients were aged 60 when the disease was discovered, and the interval between the diagnosis in the mates was 44 months. Genetic or environmental factors that could have explained the occurrence of myelomatosis were not found in these spouses. Therefore, on absence of a defined cause, our observation, like others previously reported in the literature, should be considered, although exceptional, a chance event.

Female↗
PubMed1980

[WPW syndrome and mitral valve prolapse: pathogenetic relation or coexistence? Report of a case (author's transl)].

A case of coexistence of mitral valve prolapse and WPW syndrome is reported. Even a pathogenetic relation between the two anomalies has been suggested, a constant relation was not identified in the present case. WPW conduction was intermittent and affected the phonocardiographic features of mitral prolapse, but these were also present in absence of WPW syndrome. It is concluded that a close pathogenetic relation between WPW syndrome and mitral valve prolapse has not been identified in this case. A possible coexistence of the two anomalies is suggested.

Adult↗
PubMed1980

Tococardiography in pregnancy during extracorporeal bypass for mitral valve replacement.

A 23-year-old pregnant woman with class III rheumatic heart disease, with mitral stenosis, underwent mitral valve replacement with cardiopulmonary bypass during the 32nd week of gestation. Fetal heart rate and uterine activity were recorded during the operation. Transient fetal heart rate decelerations and loss of variability, as well as uterine contractions, were observed during surgery and subsided spontaneously afterward. The pregnancy was carried to term and resulted in a normal infant. Problems associated with maternal extracorporeal circulation during pregnancy are discussed. Long-term effects on the fetus are presently unknown.

Adult↗
PubMed1980

Impact of placenta previa on intrauterine fetal growth.

The impact of placenta previa on intrauterine fetal growth was studied over a 10-year period, 1968-77. Fetal growth was assessed at the time of delivery by measurement of four parameters--birthweight, length, and head and chest circumferences. For 129 deliveries associated with placenta previa, these parameters were plotted against gestational age on Usher and McLean intrauterine growth curves. Fetal growth was significantly retarded as judged by all four parameters. When the results were analyzed according to the number of vaginal bleeding episodes, different patterns were found for the parameters studied. Retardation in chest circumference was unrelated to gestational age or number of bleeding episodes. Retardation in weight and chest circumference appeared at an early gestational age (25th week) and was more pronounced in the group with repeated episodes of bleeding. Retardation in head circumference and length appeared later (from the 32nd week of gestation) and was also more pronounced in the group with repeated vaginal bleeding. In women who had only one bleeding episode and in whom gestation continued to the 38th week or longer, birthweight, but none of the other three parameters, was consistent with the week of gestation. The results show that birthweight alone is insufficient to estimate intrauterine fetal growth retardation.

Female↗
PubMed1979

Effects of a sugar mixture on blood alcohol parameters and impairment in the intact rat.

The effects of a sugar mixture containing 43% glucose and 36% fructose on ethanol metabolism and on ethanol-induced impairment were studied in intact rats. When ethanol was given orally mixed with the sugars there was a significant reduction in the area of the blood alcohol time curve accompanied by a decrease in the peak ethanol concentration and a slowing in the rate of ethanol absorption. The whole curve followed a lower course and the time for complete removal of ethanol from the body was markedly reduced even though the slope of the elimination phase (beta) was not significantly increased. Ethanol-induced impairment as measured using a tilting plane device was significantly less when ethanol was given mixed with the sugars and paralleled the reduced area and duration of the blood alcohol curve. The magnitude of the effect observed on blood alcohol levels and impairment was dependent on the dose of sugars administered in relation to the alcohol dose. When the sugars were given orally after absorption and distribution of ethanol were complete the slope of the elimination phase (beta) was increase by 30%. These findings point to an increased rate of ethanol metabolism in rats in the presence of sugars. The action of the sugars prevails only for the first few hours after administration thereafter the rate of ethanol metabolism returns to normal.

Administration, Oral↗
PubMed1979

Activity of creatinol O-phosphate on persistent ventricular premature beats in ischemic heart disease. Double blind clinical trial.

In a double-blind investigation N-methyl-N-(beta-hydroxyethyl) guanidine O-phosphate (creatinol O-phosphate, COP) was checked versus a reference substance (solvent of COP) on volunteers affected by ischemic heart disease with persistent ventricular premature beats (VPB). COP was able to reduce VPB by 50--100% in 85% of the volunteers treated with this drug. This fact and the virtual absence of side-effects of COP lead the authors to the conclusion that COP merits more extensive investigations in this field in view of its clinical employment alone or in association with specific antiarrhythmic agents.

Aged↗
PubMed1979

Squamous metaplasia of the endometrium. Endometrial response to intrauterine presence of fibroblast-carrying Ivalon sponge.

Squamous metaplasia of the endometrium was detected in 3 women out of ten in which fibroblast-carrying Ivalon sponge (produced by implanting the sponge subcutaneously for 6 to 8 weeks) was inserted into the uterus following dilatation and curettage. The experiments were carried out in view of previous successful similar procedures in rabbits to produce fibroblastic bridges inside the uterus, and to avoid the patients from undergoing major surgery (hysterectomy) if possible, and at the same time to use the experiment as a model of contraception procedure. Since no improvement was experienced by the patients, which continued to have excessive blood loss, hysterectomies were performed at a later date, and the specimens were thoroughly examined. The possible effect of the Ivalon sponge (acting as IUCD) on the endometrium is discussed.

Adult↗
PubMed1977

Congenital hypoplastic anaemia with unusual dyserythropoietic features. A case report.

A case of severe congenital anaemia (Hb levels 3--4 g/dl) is presented. The patient, a 21-year-old female, requires, since the age of two, periodical blood transfusions, but is nevertheless able to lead a normal life as a housewife. Although the case has to be considered as a form of congenital hypoplastic disorder of the erythroid tissue, some of the clinical and haematological features are compatible with a congenital dyserythropoietic state. On the basis of clinical findings it is suggested that it may represent a previously undescribed form of anaemia which shares the features of both hypoplastic and dysplastic congenital affections of erythropoiesis.

Adult↗
PubMed1977

Ovarian abscess associated with incomplete abortion and intrauterine contraceptive device.

A 28-yera-old woman with an intrauterine device (IUD) was admitted to hospital with signs of incomplete abortion. The IUD was removed and curettage revealed necrotic infected decidua with no trophoblastic cells or chorionic villi. The patient subsequently developed multiple abscesses in the right ovary. The mechanism of development of ovarian abscesses in patients with IUD or with infected incomplete abortion is discussed.

Abortion, Incomplete↗