["Surgery and delirium tremens"].
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Biomedical subjects
Publications and source records attributed to A Naess.
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A young man with a fistula between the right femoral artery and vein due to bullet wound presented 6 years later with exertional dyspnea and palpitations and venous insufficency of the right leg. Angiography showed a wide (greater than 20 mm) arteriovenous fistula. Moderate cardiac hypertrophy and cardiac output 14.8 l/min were found. During division and closure of the fistula, 8 l/min flow was measured in the right external iliac artery. The cardiac symptoms disappeared immediately and the venous insufficiency gradually.
Twenty-six cases of squamocellular carcinomas of the lip were immunostained for p53 protein. Nuclear accumulation of p53 protein was observed in 88% of the 26 carcinomas, in 64% of adjacent "normal" epithelium and in all four cases with adjacent atypical squamous epithelium. 93% of the specimens (13/14) with p53 protein accumulation in "normal" epithelium demonstrated evidence of solar elastosis. UV radiation may induce p53 gene mutation as an early event in the neoplastic transformation.