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Biomedical subjects

A Moroni

Publications and source records attributed to A Moroni.

At least 127 records · Page 7Linked to original sources

Composite acrylic cement with added hydroxyapatite: a study of the polymerization temperature.

Varying percentages (0 to 50%) of crystalline hydroxyapatite (HA) in powder form were added to ordinary acrylic cement (PMMA). The exothermic peak of the polymerization reaction and the setting time of this compound cement were investigated. Its mechanical properties are far superior to those of ordinary cement. The addition of small percentages of HA to acrylic cement produces a sharp fall in the exothermic polymerization peak; it also increases the setting time, although this remains within time limits that are only slightly greater than those for ordinary cement.

Bone Cements↗

Pigmented villonodular synovitis of the hip. Study of 9 cases.

Pigmented villonodular synovitis of the hip is a very rare condition. The authors report 9 cases out of a total of 139 cases of pigmented villonodular synovitis of joints observed at the Rizzoli Institute in the last 35 years. They describe the clinical, radiological and pathological aspects, and discuss the problems of differential diagnosis. In particular, they discuss the indications for surgery (total synovectomy or arthroprosthesis) and the post-operative regime.

Adolescent↗

Diabetes as pro-infective risk factor in total hip replacement.

It is widely accepted that diabetic patients, above all poorly controlled ones, are more susceptible to infection. To verify whether diabetes might be considered a pro-infective risk factor in total hip replacement, 1,042 patients, who from 1969 to 1979 underwent an operation for arthropros thesis of the hip, were studied. The patients were subdivided into two groups according to whether they were diabetic or not. The diabetic patients, though well controlled by diet or by diet plus oral hypoglycemic agents, received insulin for at least two days before surgery. In the early post-operative phase they showed transient worsening of glycemic control rapidly corrected by increased insulin dosage. The patients of both groups were operated in low air exchange operating theaters, by the same staff and using standardized surgical techniques, and all received antibiotic coverage as preventive treatment against infections for a week after surgery. Infection and suppuration occurred in 11% of diabetic patients and only in 2% of non-diabetic patients (p less than 0.001); in these cases the prostheses were removed after unsuccessful antimicrobial treatment. Our study indicates that diabetes mellitus must be considered a proinfective risk factor in patients who undergo an operation for total hip replacement and suggests that a conservative approach is required in diabetic patients.

Aged↗

Migration rates of human populations from surname distributions.

Migration is an important factor in the biological evolution of human populations, and surnames provide one of the simplest records of identification. The distribution of surnames can supply quantitative information on the structure of human populations. Surnames considered as alleles of a gene transmitted only by the male line can be assumed to be neutral markers and therefore satisfy the expectations of the neutral theory of evolution, which is entirely described by random genetic drift, mutation and migration. As data on surnames are easier to collect than those from genes, the information yield is potentially increased, but the validity of the conclusions must be tested in actual samples. The purpose of this report is to compare the estimates of migration rates in Italy, as inferred by the surname distribution found in the telephone directories and other sources, with the corresponding estimates from official demographic sources. Our findings show that in these samples the ratio of surnames to individuals makes it possible to calculate reliable estimates of migration rates.

Genetics, Population↗

The effect of surface material and roughness on bone screw stability.

OBJECTIVE: To evaluate the effects of osteointegration ability and surface texture on bone screw interface stability in three different groups of titanium screws. DESIGN: Sixty titanium tapered screws were used: twenty screws were polished, uncoated (Group A); twenty screws were rough, coated with titanium (Group B); and twenty screws were rough, coated with fluor-hydroxyapatite (Group C). Thirty screws, ten per group, were implanted in the femurs and tibiae of two sheep, which were euthanized one month after surgery. The remaining thirty screws, ten per group, were implanted in the femurs and tibiae of another two sheep, which were euthanized three months after surgery. RESULTS: At one month, extraction torque of Group C was higher than that of Group A (p = 0.042). At three months, extraction torque of Group C was higher than that of Group A (p < 0.0001) and Group B (p < 0.0001). At three months, extraction torque of Group C was higher compared with the corresponding insertion torque (p < 0.0001) and compared with the corresponding extraction torque at one month (p < 0.0001). At one and three months, a high percentage of bone-screw contact was observed histologically in Groups B and C. A continuous gap with fibrous tissue encapsulation was observed in Group A. CONCLUSIONS: This study shows that the osteointegration ability provided by the type of coating is a very important parameter for optimizing the bone-screw stability. Surface texture is also important. By using screws with optimal osteointegration ability, very positive clinical consequences can be expected.

Animals↗

Two cases of cuneiform subcapitate osteotomy in the outcome of severe epiphysiolysis of the hip.

The authors describe two cases of subacute epiphysiolysis with severe slipping submitted to corrective subcapitate osteotomy of the femur with an anterior approach. The patients were followed-up after approximately 7 years, and satisfactory results were observed: movement in flexo-extension was preserved with mild limitation of intrarotation. The accuracy of the osteotomy during surgery is emphasized in order to avoid necrosis of the femoral head, and hypercorrection in valgus to avoid shortening.

Adolescent↗

The surgical treatment of cervical disc herniation.

The authors reviewed 61 cases of cervico-brachialgia due to posterolateral disc herniation treated at the Rizzoli Orthopaedic Institute between 1975 and 1985. Results were positive in 69.3% of the cases, partially negative or negative in 30.7%. An analysis of the results reveals a high correspondence between clinical diagnosis and surgical findings (82%): but the percentage of error in clinical diagnosis (18%) cannot be overlooked. For this reason the clinical diagnosis must be confirmed by CT and/or MRI. In our experience, the posterior approach has proven to be suited to resolving most cervico-brachial pain syndromes due to posterolateral disc herniation.

Adult↗