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Biomedical subjects

A Mihail

Publications and source records attributed to A Mihail.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Isolation, purification and characterization of polypeptides of influenza and parainfluenza viruses. Note III. Polypeptides of three influenza virus strains isolated in Romania.

An analysis is presented of the nature, number and relative molecular mass of the polypeptides of three influenza virus strains-A/Romania 1/73 (H3N2), A/Romania 1/75 (H3N2), and B/Romania 34/74-isolated during different epidemic outbreaks. The results obtained indicate some similarities between the protein subunits of the two influenza A virus strains (as concerns virus surface and nucleocapsid components) and point out the particular properties of the influenza B strain.

Orthomyxoviridae↗
PubMedDate not supplied

Neutralizing influenza antibodies, IgA and total protein in the nasopharyngeal secretions of subjects vaccinated by nasal route with the inactivated influenza vaccine prepared in the "Stefan S. Nicolau" Institute of Virology.

Intranasal administration of two doses of the inactivated influenza vaccine prepared in the "Stefan S. Nicolau" Institute of Virology was followed by rises in the level of neutralizing secretory influenza antibodies in 82% of the cases. The concomitant study of secretory antibody, IgA and total protein levels, as well as of the serum HAI influenza antibodies demonstrated that their evolution was parallel only in 23% of the vaccinees. The percentage of secretory antibody conversion was similar to the rate of protection conferred by the vaccine.

Administration, Intranasal↗
PubMedDate not supplied

[Epidemiological and virological research on influenza and viral respiratory infections in the southeastern region of Romania in the cold season of 1991-1992].

Investigations pointed out the high level of respiratory diseases and pneumonias in children, especially in the youngest ones (0-1 year-old) during all the surveyed period. An influenza outbreak during the second half of February was registered in the infantile population--school and low-age children--which gave most of the cases. Serology and isolations incriminated an influenza virus related to the A/Beijing 353/89 (H3N2) strain. Isolations worked out after the influenza epidemics pointed out circulation of parainfluenza and adenoviruses. The necessity is emphasized of the anti-influenza vaccination of low-age children.

Acute Disease↗
PubMedDate not supplied

[Relations between human and animal influenza viruses].

The following more important problems are dealth with in the present paper:--antigenic relationships between human and animal influenza viruses;--recombination of human and animal influenza viruses;--epidemiological relationships between human and animal influenza viruses;--the theory of cyclical evolution of influenza viruses.

Animals↗
PubMedDate not supplied

[The virological study of a certified focus of acute respiratory diseases in a half-closed community].

An acute respiratory disease outbreak appeared during February and March 1988 in a half-closed community. Virologic investigations were conducted and an influenza virus type B strain was isolated, antigenically like B/Victoria 2/87. Administration of the anti-influenza vaccine in the fifth day of the outbreak evolution led to considerable reduction of the new cases and to outbreak extinction after 48 hours.

Acute Disease↗