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Biomedical subjects

A Malinowski

Publications and source records attributed to A Malinowski.

At least 73 records · Page 4Linked to original sources

[Subpopulations of t lymphocytes and lymphocyte proliferative activity in normal pregnancy].

T lymphocyte subpopulations (CD3+, CD4+, CD8+) and the lymphocyte proliferative responses to mitogens (PHA, Con A, PWM), in the environment of fetal calf serum (FCS) were examined in 16 normal primigravidas in the third trimester of pregnancy and in 15 healthy nonpregnant women. In normal pregnant women significantly lower absolute and percentage numbers of CD3+ and CD4+ T cells and almost twice reduced CD4+/CD8+ ratio were found, in comparison with nonpregnant subjects. Despite the shifts among particular T lymphocyte subsets in the peripheral blood, non disorders were found in the lymphocyte proliferative responses to mitogens in normal pregnancy.

Adult↗

[Immunomodulating properties of sera in normal pregnant women].

The purpose of this study was to analyze the immunosuppressive properties of sera of normal pregnant women. Effects of pregnancy sera on the proliferation of mitogen (PHA, Con A, PWM)-induced lymphocytes were examined in healthy primiparas. The sera of normal pregnant women inhibited the proliferation of PHA- and Con A- induced both autologous and allogenic lymphocytes (obtained from nonpregnant and pre-eclamptic women), while remaining neutral towards the proliferation of PWM- induced lymphocytes in comparison with fetal calf serum. The basic immunomodulatory activity of the sera in pregnant women was contained in the heat-stable fraction.

Adult↗

[Concentration of heavy metals in pregnant women].

Copper, zinc, and lead concentrations were measured in two groups 72 pregnant women. Twenty-one of them, making up the control group, lived and worked in Wrocław. The other 51 women, the second group, had lived more than five years in Lubin-Polkowice and worked in the local non-ferrous metal plants. They were particularly endangered by their exposure to copper, zinc, and lead concentrations. Pregnancy was normal in all cases. Maternal blood, umbilical cord blood, placenta homogenate, and amniotic fluid were examined by techniques of atom-absorption spectrometry. The metals tested were conspicuously absorbed by placental tissue, but no danger to the pregnant women could be established.

Amniotic Fluid↗