Search PubMed⌕ Search

Biomedical subjects

A M Rywlin

Publications and source records attributed to A M Rywlin.

At least 55 records · Page 3Linked to original sources
PubMed1980

Ferrugination caused by Monsel's solution. Clinical observations and experimentations.

Ferrugination of fibrin, dermal collagen, and striated muscle fibers may result from the application of Monsel's solution (20% ferric subsulfate) for hemostasis to wounds caused by excisions of skin. The collagen fibers in the dermis are coated with a slightly refractile, gray-brown substance which is strongly positive with Perl's reaction for iron. Ferruginated collagen fibers are eliminated through the epidermis as the epidermis regenerates. Some of the ferruginated fibers become calcified. Siderophages are present in these and adjacent areas. Seepage of Monsel's solution into deeper tissues at the site of biopsy may result in ferrugination of skeletal muscle, perichondrium, and even cartilage. We applied Monsel's solution to biopsy sites caused experimentally in a rabbit and confirmed the capacity of the solution to produce ferrugination of collagen fibers and skeletal muscle. Ferrugination of collagen fibers becomes less pronounced as the wounds heal and as iron pigment is taken up by macrophages. Ferruginated fibers of skeletal muscle act as foreign bodies to elicit a granulomatous reaction. Comparison of biopsy sites to which Monsel's solution had been applied with biopsy sites to which the solution had not been applied indicates that the substance does not seem to interfere with the rate of epidermal regeneration. However, when there is injury to skeletal muscle and other deep tissues by Monsel's solution, an inflammatory reaction persists at these sites for weeks.

Administration, Topical↗
PubMed1980

Ceroid granulomas in a tubo-ovarian cyst.

We have described a previously unreported lesion--ceroid granulomas in a tubo-ovarian cyst. We postulate that the ceroid granules in the histiocytes are derived from lipids within the foamy histiocytes which are often associated with tubo-ovarian abscesses.

Adult↗
PubMed1980

Non-hodgkin's malignant lymphomas. Brief historical review and simple unifying classification.

A brief historical review and a unifying classification of the non-Hodgkin's lymphomas are presented. The principles underlying this classification are that 1) neoplastic cells are named after normal cells they resemble most; 2) the germinal center is a reaction center where small lymphocytes undergo blastic transformation as well as the birthplace of small lymphocytes; and 3) lymphoid cells can be subdivided by size and cytologic characteristics into small, intermediate, and large types. This classification can be expanded by additional qualifying terms. Whether such expansions are justified in terms of reproducibility and clinical significance remains to be proven.

History, 20th Century↗
PubMed1979

Acropustulosis of infancy.

Acropustulosis of infancy (Al) is a syndrome consisting of pruritic pustules that are found primarily on the extremities of infants. It is uncommon, but not rare, and persists about two years. In two infants in whom Al began at birth, there was a striking response to sulfones. There was no response to other therapy. Laboratory findings are not diagnostic for Al. Similar histopathologic changes (subcorneal pustules) can be found in other eruptions of infancy.

Biopsy↗
PubMed1979

Histiocytosis X.

Explore the source record for details and available documents.

Diagnosis, Differential↗
PubMed1978

Optimal enzyme test combination for diagnosis of acute myocardial infarction.

One hundred consecutive patients admitted to our cardiology service with the suspected diagnosis of acute myocardial infarction were evaluated with serical enzyme and isoenzyme determinations in an attempt to develop the medically and financially optimal combination of enzyme tests. In patients with onset of chest pain less than 24 hours before admission, creatine phosphokinase MB determination on admission and after 12 hours was sufficient to diagnose of exclude myocardial infarction. One serum LDH isoenzyme determination 24 hours after admission confirmed the diagnosis in 74% of patients.

Acute Disease↗
PubMed1977

Fine needle aspiration cytology.

Aspirations were done in 221 breasts and 32 extramammary sites with a 25 gauge needle attached to an ordinary 10 ml syringe. The aspirated material was expressed from the needle hub onto a slide, smeared by means of a second slide, air dried, and stained with a Wright-Giemsa solution. The cytologic interpretation closely correlated with the subsequent histological diagnoses. No false-positive readings were encountered. A falsely negative diagnosis was made in 11 breasts, mostly due to faulty aspiration. Widespread use of the fine needle aspiration cytology should drastically reduce the need for breast biopsies. This technic also may be used in the diagnosis of extramammary lesions.

Aged↗
PubMed1976

Metastatic carcinoma in histologic sections of aspirated bone marrow: a comparative autopsy study.

The incidence of metastatic carcinoma in bone marrow was studied by two different approaches in 220 consecutive autopsies of patients with carcinoma: histologic sections of aspirates from the iliac spine, as usually done in living patients; and gross and microscopic examination of the thoracolumbar spine. Ten percent of the autopsies showed bone marrow metastases by the aspiration technic as contrasted with 34.5% by the autopsy technic. Three cases had positive bone marrow aspirates in the absence of metastases demonstrable by routine autopsy. The combination of autopsy and aspiration technics yielded an incidence of metastatic marrow involvement of 35.9%. Of patients with marrow metastases at autopsy, 25% also had positive aspirates. This study establishes a norm for the comparison of the efficiency of discovery of metastatic carcinoma by different modalities of clinical bone marrow sampling.

Autopsy↗
PubMed1976

Effect of oxygen in graded concentrations upon tracheal mucous velocity. A study in anesthetized dogs.

Graded concentrations of oxygen were used to establish dose-duration relations for the effect of oxygen on tracheal mucous velocity and tracheobronchial histologic findings in the anesthetized dog. Observations of tracheal mucous velocity were made during 30-hour periods of breathing air (100-percent humidified and warmed to 38 degrees C) and oxygen mixtures (also 100-percent humidified and warmed to 38 degrees C). In animals breathing oxygen mixtures, the baseline tracheal mucous velocity was taken as the value while breathing room air at the experiment's start. No statistically significant differences in tracheal mucous velocity occurred during air breathing. Tracheal mucous velocity fell 45 percent from the baseline value after breathing 100-percent oxygen for two hours (P less than 0.01), fell 42 percent after 75-percent oxygen for nine hours (P less than 0.01) and fell 51 percent after 50-percent oxygen for 30 hours (P less than 0.001). Histologic examination of the trachea and major bronchi after six hours of 100-percent oxygen and 12 hours of 75-percent oxygen revealed signs of acute tracheobronchitis. Minor histologic alterations in the tracheobronchial tree occurred both in animals breathing air and 50-percent oxygen for 30 hours; therefore, histologic evidence of oxygen toxicity could not be established at 30 hours. These findings indicate that in the anesthetized dog, oxygen depresses mucous transport as a function of inspired oxygen concentration (FIO2) and that even FIO2 as low as 0.05 might be deleterious.

Acute Disease↗