[Statistical analysis of the radiographic study of the effects of low concentrations of puromycin on amino acid incorporation in amphibian embryo cells cultivated in vitro].
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Biomedical subjects
Publications and source records attributed to A M Duprat.
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The molecular mechanism of neural induction of embryonic cells is an important but poorly understood problem in neuroembryology. Glycoconjugates in the target cell plasma membrane and/or its structural organization play a key role in the reception of the inductive signal. It is the competent target tissue itself which probably contains the capacity and specificity for neuralization. However, the mechanism of transmission of the signal which leads to activation of the intracellular machinery involved in the process of neural determination remains to be elucidated. With respect to the information acquired by the target cells during neural induction, and the early events in differentiation, neuronal precursor cells have been shown to have acquired the potential to display a high degree of biochemical and phenotypic differentiation, even in the absence of further embryonic influences.