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Biomedical subjects

A Luger

Publications and source records attributed to A Luger.

At least 109 records · Page 6Linked to original sources
PubMed1984

[Urticarial vasculitis].

Knowledge of urticarial vasculitis is very important, because its therapy and prognosis are different to other clinically similar diseases, eg idiopathic urticaria. We present a 72-year-old female patient suffering from recurrent urticaria associated with slight fever, arthralgia, occasional abdominal pain, as well as highly elevated erythrocyte sedimentation rate. Histologic examination of involved skin revealed leucocytoclastic vasculitis. Corticosteroid treatment led to clinical improvement. Courses of urticarial vasculitis may vary to a high degree; the clinical spectrum of urticarial vasculitis may turn to ranges from chronic idiopathic urticaria to systemic lupus erythematosus. Clinical hallmarks of urticarial vasculitis are slowly (within 72 hours) regressing wheals, arthralgia, as well as highly elevated erythrocyte sedimentation rate.

Aged↗
PubMed1984

[Continuous arteriovenous hemofiltration in the therapy of acute renal insufficiency].

30 patients with acute renal failure were treated in an intensive care unit by continuous arterio-venous haemofiltration (CAVH). This procedure has less side effects as compared with intermittent haemodialysis, peritoneal dialysis and haemofiltration (hypotension, bio-incompatibility and lack of biochemical steady state) and CAVH is clearly superior with regard to fluid removal. In removing the uraemic toxins CAVH is more effective than peritoneal dialysis and, in most instances, satisfactory as sole renal replacement therapy in acute renal failure.

Acute Kidney Injury↗
PubMed1983

[IgM diagnosis in syphilis serology].

The methods in use for the detection of T pallidum-specific antibodies in human sera are the 19S-(IgM-)FTA-ABS and the IgM-SPHA test. Encouraging results have been obtained with the IgM-ELISA-TP technique using new antigens. The development of the different methods up to the present time are described. The margin of error is low, 3.4% of the 19S-(IgM-)-FTA-ABS results are false-positive and 3.6% false-negative, the respective figures for the IgM-SPAH test are 1% (false-positive) and 8% (false-negative). The agreement with the clinical diagnosis is excellent in the secondary stage (94 to 95% reactivity), the reasons for lower rates in the primary and late phases are discussed. The half-life period of reactivity after adequate treatment amounts to 2 to 6 months in all stages except for the IgM-SPHA test in neurosyphilis, where reactivity remains for 24 months (mean value) due to the production of autoantibodies.

Antibodies, Bacterial↗
PubMed1983

[Specificity and sensitivity of the solid phase hemadsorption test: a study of treated and untreated syphilitics].

SPHA-test was performed on 317 treated and 78 untreated patients with syphilis and partly compared to 19S-IgM-FTA-ABS- as well as VDRL-test. Equivalent results were obtained in a reference laboratory, the correspondence being 94.8 percent regarding SPHA and 95.6 percent concerning 19S-IgM-FTA-ABS. In comparison to 19S-IgM-FTA-ABS, increased numbers of weakly reactive values occurred in SPHA correlating with the Latex-test. Because of its specificity and sensitiveness, SPHA turned out to be superior to VDRL with regard to the control of treatment. The biological significance of weakly reactive SPHA results is still unclear and does not indicate a necessity for therapy.

Antigens, Bacterial↗
PubMed1983

[Recent progress in syphilis serology].

Serological investigations for the diagnosis of syphilis have been performed in a special subunit at the Department of Dermatology to Lainz Hospital, Vienna, since 70 years. At present 80,000 to 100,000 sera are tested annually. The classical test systems VDRL, TPHA, AMHA-TP and FTA-ABS demonstrate, in particular, the presence of IgG antibodies and are, thus, suitable for the diagnosis of the disease, but do not permit conclusions on the activity of the disease and the actual need for antisyphilitic treatment. The newly developed IgM diagnosis of syphilis with the IgM-SPHA- and the 19S-IgM-FTA-ABS test solve these problems and can be performed even under routine conditions using the methods of solid phase haemadsorption and computerized high pressure liquid chromatography. In addition, the serological diagnosis of neurosyphilis has been worked out by the determination of the TPHA-index and the detection of antitreponemal IgM-antibodies in the cerebrospinal fluid. The relative frequency of latent syphilis infections has increased over the past years and serodiagnosis of syphilis, thus, become more and more important. The availability of five independent test systems has enabled the elaboration of a test profile which keeps the margin of error to below 0.1%. A further method, the ELISA technique is at present under investigation and renders promising results by the use of recently developed reagents.

Cerebrospinal Fluid↗
PubMed1983

[Skin metastases of malignancies of internal organs].

In 4 cases with cutaneous metastases from internal cancer the primary tumours were found in the gallbladder, the breast, the lung and the kidney. The cutaneous metastases were the first symptom of the disease in 2 of 4 cases and led to the diagnosis. Course, treatment and prognosis of secondary skin tumours are discussed in detail.

Adenocarcinoma↗
PubMed1983

[70th anniversary of Lainz hospital].

The Krankenhaus der Stadt Wien-Lainz was the first hospital built and administered by the municipality of Vienna. It was opened on 17th May, 1913 with 8 departments (991 beds) and 3 institutes; now it consists of 14 departments (1,504 beds) and 7 institutes. The main scientific investigational fields are mentioned. 10 research units are supported by the Ludwig Boltzmann-Gesellschaft. Besides these, many other investigations are performed. 3,246 papers, handbook articles and books have been published by the physicians of the hospital during the past decade.

Academies and Institutes↗
PubMed1983

Acute changes in peritoneal morphology and transport properties with infectious peritonitis and mechanical injury.

Peritoneal clearance studies were performed in rats undergoing acute peritoneal dialysis. Some of these animals were then exposed to laparotomy and mechanical drying of the peritoneum. Peritoneal clearance studies were repeated at intervals up to 11 days. Another group of rats was placed on daily peritoneal dialysis and allowed to spontaneously develop peritonitis which was not treated. These rats underwent peritoneal transport studies at differing durations of infection. In all groups, animals were sacrificed at the time of the last transport studies for morphological assessment of the peritoneum by light microscopy, scanning electron microscopy, and transmission electron microscopy. The results showed similar decreases in drainage volume and increases in glucose absorption and protein losses with both infection and drying. Both types of injury resulted in extensive mesothelial structural changes. While drying caused mainly denudation of the mesothelial surface, infectious peritonitis was associated with separation of mesothelial cells, and the appearance of numerous white blood cells between and on mesothelial cells. Exposure to peritoneal dialysis alone had no obvious effects on anatomy. Although changes in the peritoneal microcirculation and deeper structures cannot be excluded as contributing to peritoneal transport alterations, the findings suggest that alterations of mesothelium might explain some of the changes in peritoneal transport properties under the conditions of these studies.

Acute Disease↗
PubMed1983

Spontaneous arteriovenous plasma separation.

Plasmapheresis (PP) therapy was carried out by spontaneous arteriovenous membrane plasma separation. By cannulating the femoral artery and vein by Seldinger technique, this method could be performed by natural arteriovenous pressure gradient without blood pumps or special monitoring. Eight patients experienced 44 PP therapies without complication in the ICU. Spontaneous arteriovenous membrane plasma separation can suitably be combined with continuous arteriovenous hemofiltration.

Adult↗
PubMed1983

[ Fournier gangrene: a rare complication of multiple myeloma].

A 69-year-old male patient with multiple myeloma developed a dolent swelling of the right side of his scrotum at the time of maximal leukocyte depression after cytostatic drug therapy. Within a few hours the scrotal skin became gangrenous. After surgical debridement of the necrotic tissues and simultaneous antibiotic therapy the necrosis showed a favorable course.

Aged↗