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Biomedical subjects

A Louvel

Publications and source records attributed to A Louvel.

At least 73 records · Page 4Linked to original sources
PubMed1981

[Tubular filamentous intranuclear inclusions on multinucleated cells of bone giant cell tumors].

Electron microscopy revealed tubular filamentous inclusions within nuclei of giant cells in 22 per cent of 31 cases of genuine giant cell tumours of bone. These inclusions are, both on biopsy and on culture, similar to those of osteoclasts of Paget's disease but less constant, less numerous and mainly intranuclear. Controls by the study of giant multinucleated cells from osseous and extra osseous lesions were negative.

Bone Neoplasms↗
PubMed1980

[A case of alpha chain disease in an African negro (author's transl)].

A new case of alpha chain disease is described in an African negro (Zaïre). The initial diagnosis was lymphoma, diffuse immunoblastic type. serum protein electrophoresis exhibited a normal pattern but immunoelectrophoresis demonstrated alpha heavy chain without reactivity with anti light chains antisera. It seems to be the third case of alpha chain disease in a black patient.

Adult↗
PubMed1980

[Configuration and position of centrioles in mono- and multinuclear cells of giant cell tumors of the long bones].

In multinuclear cells of giant cell tumours of long bones studied in biopsies and histiotypic cultures the centrioles were found to be grouped at a distance from the nuclei, forming a giant centrosphere made of diplosomes in equal number to that of the nuclei. This arrangement renders the possibility of new mitotic activity highly unlikely. By contrast, close contacts between multinuclear cells and stromal cells together with the collapse of membranes between cells in contact and the centriolar arrangement represent arguments in favour of genesis by fusion from mononuclear cells of stromal type, in common with many polykaryons. The multinuclear cells of these tumours would appear to represent only the final stage in the evolution of certain mononuclear cells.

Bone Neoplasms↗
PubMed1979

[Clinicopathological profile of pancreatic lithiasis (author's transl)].

Clinical, radiological and histopathological features of 31 duodenopancreatectomies for chronic pancreatitis with lithiasis are analysed in relation to whether or not there was dilatation of the duct of Wirsung. Two groups of patients may be defined in the basis of this criterion: -- the first, without dilatation of the duct of Wirsung, with lithiasis predominantly affecting the head of the pancreas and irregular fibrosis, corresponding patients aged approximately 30 years, suffering from the disease for about 10 years, often already operated upon for pancreatitis; gastrointestinal bleeding is common; -- the second, with dilatation of the duct of Wirsung, with disseminated lithiasis, and very marked fibrosis, affecting patients aged over 50 years, suffering from the disease for less than 5 years and not yet operated upon for their pancreatitis. The problem of the independance of the two groups or of the possibility of progression of forms without dilatation of the duct of Wirsung to dilated forms remains.

Adult↗
PubMed1979

[Primary lymphoid sarcomas of the stomach. Ten cases (author's transl)].

These sarcomas fall within a precise definition and must be differentiated from gastrointestinal involvement in a haematological disorder. For certain histological forms (nodular forms), the prognosis is less bad than that of carcinomas. Pre-operative diagnosis, often difficult, must be established by large biopsies. The best results are likely to result from a combination of surgery and radiotherapy or of surgery and chemotherapy.

Adenocarcinoma↗
PubMed1979

[Heterotopic pancreas. Report of 8 new cases (author's transl)].

The authors report 8 new cases of heterotopic pancreas and the clinical signs of each case. The emphasise the difficulties of preoperative diagnosis owing to their usually small size and the necessity of surgical treatment justified by the same lesions which affect the normally placed pancreas including cancer.

Adult↗
PubMed1979

[Pathology of endocrine polyneoplasms (polyadenomatoses) (author's transl)].

The term "endocrine polyadenomatoses" includes two types of pathological entities in which there are an association of at least two endocrine tumors having no physiological relationships, and hereditary familial characteristics: Wermer's syndrome (Type I): pancreatic endocrine tumor, pituitary adenoma, and hyperplasia or adenoma of the parathyroids. Sipple' syndrome (Type II): medullary thyroid cancer, one of two pheochromocytomas, and parathyroid hyperplasia. The multifocal character of the pancreatic D-cell lesions in the first type, and the bilateral nature of the thyroid and adrenal lesions in the second type are particular features of each of them. Apart from some parathyroid lesions, for which the origin is still debatable, these endocrine tumors enter into the framework of the apudomes and are derived therefore from the neural crest. The association of other tumoral varieties of the APUD (carcinoid) type with nervous tissue tumors, and with dysmorphic anomalies suggests that these syndromes are the expression of a dysgenesis affecting more or less completely, structures derived from the neural crest.

Adrenal Gland Neoplasms↗
PubMed1978

[The Wirsung's duct of in surgical chronic pancreatitis. Radiologial and anatomical study (author's transl)].

On the basis of pancreatography findings and the study of operative specimens in 32 cases of duodenopancreatectomy, it was possible to distinguish two groups according to whether or not the duct of Wirsung was dilated. When the duct was not dilated, fibrosis was relatively marked, but disseminated and more notable in sections of the head than in sections of the isthmus. Lithiasis was essentially cephalic, but distributed more or less equally between the duct of Wirsung and the canaliculi. When the duct was dilated, there was marked fibrosis, distributed equally. Lithiasis was radiologically diffuse throughout the organ, but situated in particular in the duct of Wirsung itself.

Calculi↗
PubMed1978

[Isolated and involvement in Crohn's disease (author's transl)].

Anorectal lesions in Crohn's disease are usually associated with colonic involvement. Under other circumstances, they reflect an additional localisation of the disease, being indicative of its progression. However, they may remain strictly isolated and pose a diagnostic problem. The authors report here a case of anoperineal lesions which remained isolated after a 5 year course of the disease and which led to the need for anoperineal excision.

Aged↗
PubMed1978

[Diverticulosis of the small intestine (author's transl)].

The authors report two cases of acquired diverticulae of the small intestine with complications and study of pathological, clinical and therapeutic characteristics of this rare disease. Usually latent, these diverticulae were recognised generally during diverticulitis, intestinal obstruction, perforation or hemorrhage. The treatment was either removal of the diverticulum or segmental resection of the small intestine. Diverticulitis of the terminal ileum may lead to right ileo-colectomy.

Adult↗
PubMed1978

[Acute pancreatitis. Superficial capsular necrosis and parenchymatous involvement. 115 cases, 11 resections (author's transl)].

The authors report 115 cases of acute pancreatitis who were either operated on or autopsied and emphasise the severity of the glandular parenchymatous involvement which remains, furthermore, difficult to recognise during manual exploration. Necrosis is sometimes limited to the peripheral interstitial tissue and spares the gland itself (the prognosis is then less serious) and has led many surgeons to resections which did not always seem justified a posteriori. The authors refer to pancreatic decapsulation, described by rumanian authors, and suggest a method of operative diagnosis of the extent of glandular necrosis.

Humans↗
PubMed1978

[Angioimmunoblastic lymphadenopathy (AIL) rich in epithelioid cells presenting a Gougerot-Sjögren syndrome. Nosological relationship between Sjörgen "pseudolymphomas" and AIL (a case with a fatal course)].

The authors report the case of a 62-year-old woman in whom, 18 months following the development of bilateral parotid hypertrophy followed by a dry syndrome, there was the onset of an angioimmunoblastic lymphadenopathy (AIL) which consisted of the association of a multiple lymphadenopathy with a characteristic histological appearance, although poor in plasmocytes, and a febrile syndrome, but in the absence of a complete syndrom from a laboratory standpoint. This fact, incombination with the richness of the nodes in epitheloid cells, is such that this case resembles the type II "dysimmune and pseudo-lymphomatous lymphadenopathies" (DPLL) of Delsol et al. Although the term AIL has never been used before in the title of previous publications of pseudo-lymphomas occuring during Sjögren's syndrome, it would seem possible, as has already been suggested by Diebold et al. (3) with regard to several cases, that certain of these pseudo-lymphomas are true AIL. The rapidly fatal course with visceral spread shown at autopsy and above all the presence of exclusively immunoblastic plaques in several mode areas led, on the basis of the criteria of Nathwani et al. (22), to acceptance of the coexistence of an immunoblastic sarcoma.

Aged↗