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Biomedical subjects

A Longo

Publications and source records attributed to A Longo.

At least 127 records · Page 7Linked to original sources
PubMed1981

HLA segregation of human T-cell subpopulation markers.

Antisera recognizing subsets of human T lymphocytes can be produced by planned immunizations involving HLA-A and HLA-B compatible donors. The reactivity of these antisera against some individuals of a population, but not others, show that they recognize a polymorphic cell surface component. The study of informative families shows the HLA linkage of at least some of these alloantigenic determinants.

Antibody Specificity↗
PubMed1981

Human T lymphocytes subpopulation as defined by alloantigens and FC receptors a comparative analysis.

Human peripheral T cells were fractionated in accordance to their surface receptors for G or M immunoglobulins and analyzed for their reactivity with alloantisera obtained by planned immunization involving HLA-A and HLA-B compatible individuals. These alloantisera were previously shown to recognized polymorphic structure exclusively expressed on T cells. Although the majority of the alloantisera analyzed reacted with different proportions of both T(M) and T(G) populations, some antisera specifically recognized surface structure restricted to either T(M) or T(G) lymphocytes. The various alloantisera consistently reacted with a fraction only of T(G) and T(M) cells, this indicating that these T cell subsets can be further fractionated in accordance to the expression of the alloantigenic determinants recognized by these antisera.

Animals↗
PubMed1981

[Reevaluation of the electrocardiographic criteria of left anterior hemiblock associated with lower infarction].

UNLABELLED: A vectocardiographic (VCG) study of 90 consecutive cases of acute inferior myocardial infarction (IMI) was carried out by Frank's method. The overall incidence of intraventricular block was 40% and that of left anterior hemiblock (LAH) 20% (18 cases). The ECG features of the 18 cases of LAH-acute IMI and of the 55 cases of isolated acute IMI were compared with those of 100 cases of confirmed chronic IMI comprising 50 cases of isolated infarction-LAH (on VCG) and with 50 cases of isolated LAH (clinical and VCG diagnosis). The incidence of the six following electrocardiographic criteria were studied: 1) terminal negative forces in Lead II and positive forces in AVR with left axis deviation 2) W-shaped appearances in Leads II and AVF, 3) initial notching in Leads II, III and AVF, 4) abnormal growth of the R wave from Lead II to Lead III, 5) combinations of the four preceding criteria taken two by two, 6) the association of 3 of the 4 preceding criteria (from 1 to 4). RESULTS: A) Acute IMI: 1) isolated infarction: criteria 1 - 7%; 2 - 2%; 3 - 5%; 4 - 2%; 5 - 4%; 6 - 0%; 2) IMI - LAH: 33%, 56%, 61%, 17%, 50%, 6%, respectively. B) Chronic IMI: 1) isolated infarction: criteria 1 - 4%; 2 - 8%; 3 - 6%; 4 - 10%; 5 - 8%; 6 - 0%; 2) IMI - LAH: 72%, 22%, 60%, 74%, 42%, 44%, respectively. C) Isolated LAH: criteria 1 - 80%; 2 - 0%; 3 - 4%; 4 - 20%; 5 - 20%; 6 - 0%. CONCLUSIONS: Some of the ECG criteria studied were relatively sensitive and were suggestive of the association IMI - LAH, but VCG was much more sensitive and specific. Therefore, the incidence of LAH associated with acute IMI is probably underestimated by ECG alone.

Electrocardiography↗
PubMed1980

[Experimental study of the use of tissue adhesives in colonic surgery].

The authors report the own experience about the experimental use of tissue adhesive in the colonic surgery, on 14 rabbits, with quite satisfactory result. Therefore they evince that this tissue adhesive, althought it can't replace the surgical suture, yet it can help the surgeon out of a hard colonic anastomosis.

Animals↗
PubMed1979

[Our experience in laparoscopic diagnosis in general and emergency surgery (author's transl)].

After a brief review of the history of laparoscopy starting from the first endoscope, the authors remark on the great usefulness, ease, and essential harmlessness of the procedure. They list all the possible uses of laparoscopy in general and emergency surgery, exemplifying their claims with the illustration of personal cases and recommending widespread use of the method in surgery.

Acute Disease↗
PubMed1979

[The indications for laparoscopy in the diagnosis of hemoperitoneum (author's transl)].

In consideration of the well-known difficulties associated with the precise diagnosis of hemoperitoneum, the authors offer their personal experience in support of laparoscopy as a diagnostic aid in such dramatic events. They review 23 cases of emergency laparoscopy performed in the First Institute of Clinical Surgery of the University of Catania between January 1978 and January 1979. Recalling that the procedure was applied to patients as young as 3 and as old as 80, they confirm the opinion expressed from other quarters, namely that laparoscopy is an essentially harmless and rapid procedure conducive to very accurate diagnosis in view of appropriate planning of therapeutic treatment.

Adult↗
PubMed1979

[Aimed liver biopsy in the course of laparoscopy (author's transl)].

Following a discussion of the various methods that have been devised for liver biopsy, and an explanation of the advantages accruing from aimed liver biopsy in the course of laparoscopy, the authors express their preference for this method on account of its unquestionable diagnostic value, ease of execution, and freedom from complications. Accordingly, and in good agreements with other experts such as Kalk, Beck, and Dagnini, they advocate more widespread use of the procedure in liver pathology.

Biopsy, Needle↗
PubMed1979

Markers of human T cell subsets identified by alloantisera.

Analysis by the indirect fluorescence test followed by fluorescence-activated cell sorter (FACS) analysis has shown that antisera recognizing subsets of human T lymphocytes can be produced by planned immunizations involving HLA-A and HLA-B compatible donors. The reactivity of these antisera against some individuals of a population but not others shows that they recognize a polymorphic cell surface component. The reactive subpopulation largely overlaps with the JRA+ subset, which was previously shown to possess regulatory properties in functional assays. The specificity of the antisera for a T cell subset and the unrelatedness of the anti-B cell activity of the same antisera has been confirmed by two-color fluorescence tests.

Antibody Specificity↗