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Biomedical subjects

A Kraus

Publications and source records attributed to A Kraus.

At least 109 records · Page 6Linked to original sources
PubMed1975

[Stereochemistry and mechanism of the methanol oxidase from Candida boidinii (author's transl)].

Under nitrogen atmosphere, methanol oxidase isolated from Candida boidinii catalyzes no hydrogen exchange of ethanol. Reactions with (1R)[1-3H]ethanol or (1S)[1-3H]ethanol occur stereoselectively. The ratio of hydrogen abstraction in the oxidation of ethanol is about 7:1 in favor of the pro R hydrogen atom. The isotope effect kH/k3H is 2 - 2.5 for (1R)[1-3H]ethanol. The isotope effects on Km and V have been determined for four different deuterium-labelled ethanols. The Km for [2H3]methanol is nearly twice that for CH3OH. That is about the same ratio as for ethanol/methanol. For the oxidation of CH3OH and 2H3COH, the ratio of VH/V2H3 = 2.44, while the ratio for methanol/ethanol is only 1.3. It has been conformed that catalase from bovine liver eliminates only the pro R hydrogen atom from ethanol. The isotope effect for the catalase-catalyzed oxidation of (1R)[1-3H]ethanol is 2.1.

Alcohol Oxidoreductases↗
PubMed1971

Validity of computer interpretation of the electrocardiogram.

Evaluation of the accuracy of computer interpretation of 2019 standard 12-lead ECG's has been carried out. In 762 records defined as normal by the cardiologist the computer agreed in 41%, found 49% with minor "abnormalities" and read 10% as having gross abnormalities.There were 1257 abnormal records. The computer read 43 of these as normal including five with infarction and three with LVH. Agreement in the various abnormal categories ranged from 31% to 85% and even after review disagreement remained in 33% of cases.

Bundle-Branch Block↗