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Biomedical subjects

A Kint

Publications and source records attributed to A Kint.

At least 73 records · Page 4Linked to original sources

Iododerma.

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Aged↗

[Histochemical and ultrastructural study of cytochrome-oxydase in basal cell epithelioma].

The activity of cytochrome-oxydase is less pronounced in the basal cell epithelioma than in the basal cells of the surrounding normal epidermis. The electron microscopic study of the localisation of the enzyme reveals that the cells of the basal cell epithelioma contain two types of mitochondria, the first of which having the same size as the epidermal mitochondria, and the other being giant mitochondria. The latter seem to be less active. The weak reactivity of the basal cell epithelioma for cytochrome-oxydase is probably due to the reduction of the cristae in mitochondria and to the functional deficiency of the giant mitochondria.

Basal Cell Carcinoma↗

[Granulomatous cheilitis and Crohn's disease].

A case of Cheilitis granulomatosa is described. The various etiologic hypotheses concerning the disease are summarized and a relation with Crohn's disease is emphasized in this case. The Cheilitis granulomatosa Miescher is to be considered as a cutaneous symptom which can be observed in various diseases (e.g. sarcoidosis, herpetic infections. Crohn's disease, panniculitis).

Cheilitis↗

On the occurrence of sphaeridia in basalioma cells and the basal cells of the overlying epidermis.

302 nuclear sections of basalioma cells, 145 nuclear sections of the basal cells of the epidermis above the tumor, and 177 nuclear sections of the basal cells of normal epidermis were investigated and statistically evaluated with the aim of determining the presence of sphaeridia occur significantly more frequently in the basal cells of the epidermis above the tumor and in normal epidermis than in the tumor itself. These findings are discussed in connection with the degree of cellular protein synthesis.

Basal Cell Carcinoma↗

Lichen sclerosus et atrophicus: an electron microscopic study.

The ultrastructural changes in seven cases of lichen sclerosus et atrophicus are described. An interesting epidermal alteration was the presence of collagen fibrils in the intercellular space; furthermore, the basal cells were altered by condensation and homogenization of the tonofibrils. The basement membrane was not uniform and often multilayered. The anchoring fibrils were numerous. In the cutis intertwining strands of fine filaments, bundles of immature collagen and normal collagen could be found. In lichen sclerosus et atrophicus the dermo-epidermal interrelationship is disturbed.

Basement Membrane↗

[Ultrastructure of solid basalioma. A morphometric study (author's transl.)].

A morphometric investigation was made on mitochondria of basalioma cells and the cells of the basal layer of the epidermis lying over the tumor. The mitochondria of the basalioma cells occupy 4.7% and of the epidermal basal cells 5.3% of the cytoplasm. The number of mitochondrial sections yields a relation of 6.6:10 in favor of the epidermal cells. These results demonstrate an alteration in the size of the basalioma cell mitochondria. The possible causes of this mitochondria enlargement were discussed. An attenuation of the activities of the mitochondrial, membrane-bound enzymes in the basalioma cells is caused in all probability primarily by a reduction of the cristae material in comparison to the basal epidermal cells. The nucleus-cytoplasm relation amounts to 6.3:10 in the basalioma cells and 3.0:10 in the basal epidermal cells.

Basal Cell Carcinoma↗