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Biomedical subjects

A K Pandey

Publications and source records attributed to A K Pandey.

At least 73 records · Page 4Linked to original sources
PubMed1981

Osseous haemangiomas.

Osseous haemangiomas are rather rare. They usually present with vague symptoms and bizarre radiological pictures. Clinical suspicion and radiological speculation can only be confirmed by proper histopathological examination. Localised lesions are curable following excision. Others should be subjected to radiotherapy. This paper presents observation on 29 cases of osseous haemangiomas.

Bone Neoplasms↗
PubMed1981

Pigmented villonodular synovitis with bone involvement.

Pigmented villonodular synovitis with bone involvements have been reported at various sites. The mode of bone involvement is still controversial. In the present report, out of 47 cases of pigmented villonodular synovitis there were six osseous involvements (at ankle, wrist, elbow, scapula, hip and knee) with bizarre manifestations. The lesions at ankle, wrist and elbow were peculiar, mimicking neoplasm. All cases were treated by operative methods.

Adolescent↗
PubMed1981

Experimental ancylostomiasis in Swiss albino mice: adrenal and thyroid histopathology.

Remarkable hypertrophic changes were observed in the adrenal and thyroid glands of male mice after 7 to 16 days of infection with the filariform larvae of Ancylostoma caninum, but not in females. The adrenal gland revealed enormous enlargement of cells in the zonae glomerulosa, fasciculata and medulla, and also the formation of big vacuoles in the glomerular zone, whereas the thyroid gland showed distinctly hypertrophied follicular epithelium with marked acolloidal condition and follicular mass formation. These changes in the cellular diameter were highly significant (P greater than 0.001 to less than 0.005). The possible reasons for hyperactivity of these glands are discussed.

Adrenal Cortex↗
PubMed1980

"T"-osteotomy of the calcaneum.

The relative length and height of the lateral and medial walls of the calcaneum probably govern the production and persistence of structural hindfoot deformity, forefoot supination and adduction, and pronation and abduction. Anatomical restoration of the proportions of the calcaneal walls forms the basis of the T-osteotomy of the calcaneum. We have undertaken this operation on 72 feet in 60 patients for cavovarus deformity with forefoot adduction. The calcaneum is approached from the lateral side and the T-shaped osteotomy is performed through the body, the vertical limb being 1 to 1.5 cm behind and parallel to the calcaneo-cuboid joint. The horizontal limb starts from the centre of the vertical cut and ends above the attachment of the tendo achillis. The postero-inferior segment is pushed out correcting the heel varus and at the same time broadening the heel. The forefoot is manipulated downwards and outwards to correct the residual cavus and the adduction and supination of the forefoot. The over-all results, with an average follow-up of 3.7 years, have been satisfactory.

Adolescent↗
PubMed1980

Total protein concentrations in human amniotic fluid from normal and twin pregnancies.

Total protein concentrations (TPC) in the human amniotic fluid, during 19 to 40 weeks of gestation, from normal and twins pregnancies were compared. In the normal pregnancies the protein concentrations were found to increase with progressing gestation, but to decrease gradually to the term. TPC fluctuations also showed a similar pattern in the twin pregnancies. There was no significant difference in the total protein contents between the normal and twin pregnancies, which probably indicates that the majority of the proteins originate from maternal source.

Amniotic Fluid↗
PubMedDate not supplied

Efficacy of amphotericin B in multi-drug resistant kala-azar in children in first decade of life.

Fifty children in the first decade of life, and suffering from multiple drug resistant kala-azar, confirmed by demonstration of amastigotes in aspirates of bone marrow or spleen were treated with amphotericin B in gradually increasing dosage to a total dose of 20 mg/kg. All patients had classical features of severe kala-azar, and had taken more than one course of antimony and pentamidine, and three patients had taken one additional course of ketoconazole besides many courses of antimony and pentamidine. The clinical response started just after first infusion in 8 patients, and the patients became afebrile. By 5th infusion, all looked better and 18 patients became afebrile. By 15th infusion all patients were afebrile and cheerful. Their spleens became smaller and body weights and total white cell counts increased. Forty eight patients had parasitological cure at the end of treatment, and only 2 patients required an additional 5 infusions for parasitological cure. All patients were ultimately cured. No one relapsed within six months of follow up. All patients had shivering, rigor and rise of temperature on the day of infusion, which could be minimized with prior administration of low dose of hydrocortisone, but could not be eliminated. Eighteen patients had loose motions during treatment, while 14 patients had decrease in appetite which improved quickly when the treatment was over. Fourteen patients had transient rise of blood urea, in six patients serum creatinine also increased and 16 patients had a minor fall in serum potassium.(ABSTRACT TRUNCATED AT 250 WORDS)

Amphotericin B↗