Search PubMed⌕ Search

Biomedical subjects

A Jacobs

Publications and source records attributed to A Jacobs.

At least 379 records · Page 21Linked to original sources
PubMed1974

Effects of procaine and lignocaine on electrical and mechanical activity of smooth muscle of sheep carotid arteries.

1 Procaine in concentrations up to 20 mM facilitated or induced electrical and mechanical activity in arterial smooth muscle, even with tetrodotoxin present.2 Procaine (up to 20 mM) caused relaxation when electrical activity was blocked by prior potassium depolarization.3 Procaine (1 mM) reduced mechanical responses to noradrenaline (1 muM) which were not accompanied by action potentials. It generally reduced mechanical responses to noradrenaline (1 mM) while increasing electrical activity induced by this.4 Lignocaine (1 mM) did not facilitate electrical activity significantly; it relaxed arteries in saline or potassium-rich solution and reduced mechanical responses to noradrenaline.5 High concentrations of procaine (at least 80 mM) or lignocaine (at least 20 mM) blocked electrical activity and caused contraction followed by relaxation and complete unresponsiveness.

Animals↗
PubMed1974

A system for data processing in haematology.

The data processing problems which arise in the provision of a modern haematology service are discussed in the light of available resources, and the basic requirements of any automated data processing system are defined. The differences between the needs of haematology and those of other pathology specialities are emphasized. A strategy for the development of a simple system which covers data capture, analysis, and retrieval is described. Separation of the short-and long-term functions of the system provides a relatively simple, inexpensive solution which can be modulated to meet the particular circumstances of each laboratory.

Computers↗