[History of the opening of the 1st x-ray facility in the Urals].
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Biomedical subjects
Publications and source records attributed to A I Novikov.
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The article presents results of examinations of 70 patients with congenital heart diseases with phenomena of secondary septic endocarditis subjected to the intravenous irradiation by quantum generators by the method described. A considerable positive effect of the intravenous laser irradiation on the development of septic endocarditis was confirmed by clinical and laboratory findings. The immunological examination of 8 patients from this group has revealed an immunostimulating effect of the intravenous laser irradiation: elevated concentration of immunoglobulins in blood, increased amount of immune-competent cells. A conclusion is made that the intravenous laser irradiation is an effective method of correction of the immune deficient states in congenital heart diseases.
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Different forms of dysentery, especially those caused by Sh. sonnei and Sh. flexneri, have been found to differ considerably in their cyclic recurrence. The development cycles of the epidemic processes of dysentery have an objective character, occur in the presence of any tendencies in the morbidity rate, and depend on the natural factors. Thus, the cycles of increase and decrease in morbidity are 3, 6, 9, 12 years for dysentery caused by Sh. sonnei and 6, 7, 8 years for dysentery caused by Sh. flexneri.
By means of light and electron microscopy methods during embryonal and postembryonal periods in birds (Gallus domesticus L.) myocardial reparative processes have been studied after its lesions produced with electrothermocoagulation. Primary closing of the wound in the cardiac wall of 3- and 5-day-old chick embryos is connected with certain reactive changes in epicardium and endocardium. In 7-10 days the cardiac wall completely restores its integrity by an intensive growth and development of intact cardiac areas. A weak development of the myocardial connective tissue stroma contributes to it. Reparative processes in the cardiac wall of 18-day-old chick embryos and in newly hatched chickens proceed with an active participation of the connective tissue, which subsequently forms a scar at the place of the lesion. Isolated redifferentiating cardiomyocytes surrounded with the connective tissue are subjected to atrophy on the 45th-60th day.
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A total of 102 radical cystectomies have been conducted for 1996-2001 (94 males, 8 females, age 37-78 years, mean age 57.5 years). Most of the patients (81.4%) were diagnosed to have transitional cell carcinoma. Supravesical urine derivation was made by means of ureterocutaneostomy and transureteroureteronephrostomy in 7(6.9) patients, ureterosigmoanastomosis--in 41(40.2%), Sigma-rectumpouch--in 1(0.9%) patients, ileocystoplasty, largely by Hautmann and Studer was carried out in 52(51%) patients. Postoperative complications developed in 25(24.5%) patients who often had adhesive ileus. Four patients died: 2 of pulmonary artery thromboembolism, 1 of acute cardiac failure and 1 of sepsis. Methods of continence urine derivation were preferred, such as ureterosigmoanastomosis by Mainz-Pouch II and creation of orthotopic bladder of the ileum.
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The paper presents the results of 114 radical cystectomies made in 1996-2002. The age of 114 patients (103 males, 11 females) ranged from 37 to 78 years (mean age 57.5 years). Transient cell carcinoma was diagnosed in 81.5% patients. Supravesical urine derivation was conducted by means of ureterocutaneostomy and transureteroureteronephrostomy in 9 (7.9%) patients, ureterosygmoanastomosis--in 43 (37.7%) patients, artificial orthotopic urinary bladder was created in 7 (6.1%) patients of a gastric segment and in 55 (48.2%) patients of the ileum. Postoperative complications were observed in 28 (24.6%) patients, intestinal obstruction being a prevailing complication. Five patients died: 2 of pulmonary artery thromboembolism, 1 of acute cardiac failure, 1 of sepsis and 1 of gastric bleeding. Continent methods of urine derivation were preferred, such as ureterosygmoanastomosis by Mainz-Pouch II and creation of orthotopic urinary bladder of the stomach or of the ileum.
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Urinary bladder plastic repair with a gastric segment on a. et v. gastroepyploici dex was made in 22 patients (18 males, 4 females, mean age 58.2 years) from November 2001 to June 2003. Gastrocystoplasty was made in 17 patients after radical cystectomy for urinary bladder cancer, and in 5 patients with neurogenic and small urinary bladder. Three patients have undergone surgery in our modification with a complete cross resection of the gastric body with the lesser curvature. Lethal outcomes were absent. Follow-up for 2-22 months demonstrated that all the patients achieved positive functional results and good quality of life.