Biomedical subjects
Publications and source records attributed to A I Esakov.
The surface of an adult rat tongue was investigated by scanning microscopy. Structural organization of the chemo- and mechanoreceptor formations of the tongue was described and their topographic chart was drawn on the basis of the experimental material. An attempt was made to explain the functional significance of these formations.
The changes in the formation of pores of the taste bulb on the rat tongue was investigated by scanning electron microscopy. The heterochronic maturation of the lingual chemosensory auxiliary apparatus at different periods of postnatal ontogenesis was shown. The pores first appeared in the papilli localized on the radix and the dorsum of the tongue and later along the lateral lingual surface.
Explore the source record for details and available documents.
The structure of catecholamine-containing dumb-bell shaped cells of the taste buds was studied by luminescent microscopy in the epithelial layer of the frog's tongue (Rana temporaria). On the unilateral section of the lingual nerve, a maintained adrenergic innervation of vessels and of the epithelium was observed, a decreased number of dumb-bell shaped cells in the taste bud, and their significant enlargement, and increased cathecholamine luminescence. With desympathization, no adrenergic nerves were observed on the vessels and the epithelium of the tongue. The size of the taste buds in desympathized cells of the tongue is sharply decreased and their number is increased. There is a tendency to grouping of the dumbbell shaped cells into 3--4 taste buds in one fungiform papillina. The experiments with sensory and sympathetic denervation of the frog tongue distinctly showed the trophic action of sensory and sympathetic nerves on the taste organ of the frog.
An electrophysiological method was used to study the centrifugal inhibition of the impulse activity of taste receptors of the frog tongue. A deficiency of catecholamines in the organism (reserpinization) or perfusion of the adrenaline-blocking agents through the lingual vessel (propranololi hydrochloridum, dibenamine) were found to prevent the centrifugal inhibition, while perfusion with an adrenomimetic agent (epinephrine) enhanced this effect. Such effects of the adrenergic agents were also observed in the animals which were subjected to desympathization by bilateral extirpation of the first ganglion of the sympathetic chain. A conclusion was drawn that catecholamines in the papilli were necessary to obtain the central inhibition influences on the function of the taste receptor apparatus.
The role of the lingual nerve fibers in the transmission of mechanosensory information from the receptors of the tongue and oral cavity of a cat was studied. A chart of the afferent innervation of both mechanosensory surfaces of the tongue (dorsal and ventral surfaces) with fibers of the anterior medial and posterior branches of the lingual nerve was drawn up on the basis of the experimental material. Different ratios of the mechanoreceptor reactions were described.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.