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A Hrycek

Publications and source records attributed to A Hrycek.

At least 55 records · Page 3Linked to original sources
PubMed1991

[Spontaneous migration and adherence of leukocytes and the NBT test of peripheral blood neutrophils in patients with iron deficiency anemia].

Literature reports suggest that iron-deficiency may contribute to the development or intensification of the condition termed generally "immunodeficiency". In the available literature no reports were found on a precise evaluation of the functions of peripheral blood neutrophils in iron deficiency anaemia. The purpose of the presented study was: 1) estimation of the adherence of neutrophils from peripheral blood to fibres, 2) evaluation of the indices of spontaneous and latex-stimulated NBT reduction by the neutrophils, and 3) the test of spontaneous migration of peripheral blood leucocytes. The study of 20 patients with iron-deficiency anaemia, with counts of total leucocytes and absolute neutrophil count in peripheral blood showed increased adherence of the neutrophils and reduced spontaneous migration of leucocytes in the 3-hour test, but no changes in the test of spontaneous and latex-stimulated NBT reduction. In the discussion an interpretation of the observed abnormalities in the studied biological functions of the neutrophils in patients with iron-deficiency anaemia is tentatively put forward, stressing that in this anaemia despite absence of changes in the counts of peripheral blood neutrophils, spontaneous migration of peripheral blood neutrophils in the 3-hour test is reduced, perhaps as a result of increased adherence of neutrophils.

Adult↗
PubMed1989

[Evaluation of the phagocytic activity of peripheral blood neutrophils in patients with hyperthyroidism].

In 80 women with hyperthyroidism (40 with diagnosed Graves disease and 40 with hyperactive nodular goiter) the following tests related to the function of peripheral blood neutrophils have been carried out: 1. nitrotetrazolium blue (NRT) reduction test. 2. evaluation of phagocyting activity by using latex particles and living bacteria cells, and 3. determination of immunoglobulin concentration and the C3 component of the complement in blood serum. The following features were found in the patients with hyperthyroidism: 1. the elevated values of the index of spontaneous NBT reduction which return to normal following the treatment with propranolol or metizol lasting 14 days, 2. a decrease in the phagocyting activity of neutrophils occurring with stimulation of phagocytosis by both the latex particles and bacteria cells. 3. the return to normal values of the index of neutrophils phagocyting the latex particles following two-week treatment with propranolol or metizol. It was concluded that in patients with hyperthyroidism the changes in NRT reduction and phagocyting activity of peripheral blood neutrophils return to normal following the two-week treatment of these patients with both propranolol and metizol.

Adult↗
PubMed1988

[Peripheral blood neutrophils in automobile tire factory workers in the light of cytochemical studies].

In 73 workers producing rubber mixtures and tubes the number and percentage composition of white peripheral blood cells as well as the NBT reduction test and cytochemical reactions to lactic (LDH) and succinic (SDH) dehydrogenases in neutrophils were estimated. The amount and percentage composition only slightly differed from controls. The NBT reduction index and the reactivity of LDH and SDH tests in neutrophils were elevated.

Adult↗
PubMed1984

[Cytochemical analysis of selected dehydrogenases in peripheral blood leukocytes of workers exposed to polychlorinated pesticides].

In 36 workers occupationally exposed to polychlorinated pesticides (Gammexane, DDT) and in a control group, cytochemical investigations of lactate and succinate dehydrogenases (LDH and SDH, respectively) in peripheral blood leukocytes were performed. In comparison with the control group, in workers exposed to pesticides, reduction of colour intensity in neutrophiles for SDH and in lymphocytes both for SDH and LDH was observed. In discussion, an attempt was made to interpret the obtained investigation results which seem to indicate disturbances in pyruvate metabolism in peripheral blood lymphocytes.

Adult↗