Search PubMed⌕ Search

Biomedical subjects

A Helgeland

Publications and source records attributed to A Helgeland.

65 records · Page 4Linked to original sources

The association between blood pressure and serum cholesterol in healthy men: the Oslo study.

The association between serum cholesterol and blood pressure (BP) has been studied in 16 525 men. The study reveals that these Oslo men in their forties present with a serum cholesterol value which is on average 0.71 mmol/l (27.4 mg/100 ml) higher at diastolic BP greater than 110 mmHg than at BP less than 70 mmHg. According to earlier studies in Oslo, this cholesterol difference alone imparts a 10-year myocardial infarction morbidity difference of 25--30%. These findings might be of practical importance for epidemiological studies and for preventive measures against the two factors. The influence of other variables on the association between blood pressure and cholesterol has been studied in a multivariate analysis. Of these variables, only body mass index and serum triglycerides significantly influence the relationship between blood pressure and cholesterol, whereas age, cigarette smoking, non-fasting blood sugar, season, socioeconomic status, and physical activity at work and leisure do not influence the correlation.

Adult↗

Coronary risk factors in various occupational groups: the Oslo study.

Coronary risk factors (CRF) have been recorded for nearly 15 000 men aged between 40 and 49 living in Oslo in 1972. These data are matched with the 1970 census data for Norway so as to analyse CRF within various occupational groups. A fairly good agreement between mortality statistics for Norway and CRF was found in many occupations. For instance, persons in pedagogical work have low total mortality rates consistent with their low coronary risk factors. Taxi and busdrivers, on the other hand, have been reported to have mortality rates from lung cancer and coronary heart disease consistent with their high smoking prevalence, serum triglycerides, and cholesterol levels.

Adult↗

Coronary risk factors and socioeconomic status. The Oslo study.

Coronary heart-disease (C.H.D.) had been reviewed as a "manager's disease". However, deaths from C.H.D. are now said to be more common in groups from the lower social classes than in those of higher socioeconomic status. We have examined wheather these differences in C.H.D. mortality can be explained by differences in the conventional risk factors for C.H.D.

Adult↗

The intercorrelation of serum cholesterol, cigarette smoking and body weight. The Oslo Study.

A screening for coronary risk factors in 18 000 Oslo men yielded 16 525 "healthy" men, aged 20-49. The intercorrelation of serum cholesterol, body weight and cigarette smoking was found to be more pronounced than described in other studies. Increasing daily exposure to cigarette smoke in the order: never-smoker, ex-smoker, non-inhaling smoker, inhaling smoker and present non-filter smoker, was parallelled by increasing cholesterol levels, but not by increasing body weight. Daily cigarette-smokers had lower body weight and higher serum cholesterol values than never-cigarette-smokers, with the exception of the 20+ cigarette-smokers who had higher serum cholesterol values and body weight than the never-cigarette-smokers. As regards ex-cigarette-smokers, both body weight and serum cholesterol tended to increase with the number of cigarettes smoked before quitting. Possible explanations of these findings are discussed.

Adult↗

Risk factors and raised atherosclerotic lesions in coronary and cerebral arteries. Statistical analysis from the Oslo study.

In 1972-1973, about 16,200 men living in Oslo, aged 40 to 49 years, were examined for cardiovascular disease, and had a number of coronary risk factors measured. This report gives the results of 129 autopsied cases with regard to the association between raised atherosclerotic lesions in coronary and cerebral arteries and various coronary risk factors. For coronary raised lesions, the high density lipoprotein (HDL) cholesterol ratio was the most significant risk factor. Systolic blood pressure and total serum cholesterol were also significantly associated. Physical activity at work and at leisure, nonfasting triglycerides, and cigarette smoking did not show a significant association with coronary artery raised lesions. The association between total serum cholesterol and systolic blood indicates that total serum cholesterol may be more important than systolic pressure in the synergism affecting the development of coronary atherosclerosis. For cerebral artery raised lesions, blood pressure was the most important risk factor, even though serum cholesterol was highly associated with the lesions. The interaction analysis also suggested that blood pressure was more important than serum cholesterol in the synergism.

Adult↗