[Epidemiologic study of cardiovascular diseases in Hokkaido--with special reference to hypertension, diabetes mellitus and ischemic heart disease].
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Biomedical subjects
Publications and source records attributed to A Hashimoto.
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Functional change in the left ventricle was studied in the light of changes in the left ventricular (LV) volume preload before and after Fontan's operation. Six cases with tricuspid atresia (TA) were studied, and they had either types Ib or IIb. The preoperative LV end-diastolic volume index (LVEDVI) was 123 +/- 44 ml/m2, which corresponds to 166% +/- 45% of normal values. This suggests that in TA the preload of the LV volume is increased because of its peculiar hemodynamic situation. After Fontan's operation, the LVEDV decreased by 24.6% to 119.6 +/- 87.7 ml (P = 0.01), which corresponds to 120% +/- 50.9% of normal values. Presenting a striking contrast to the decrease in LVEDV, the postoperative reduction in LV end-systolic volume (LVESV) was approximately 8%. Preoperative and postoperative values for LVESV were 67.1 +/- 50.8 ml and 62 +/- 45.6 ml, thus, the systolic volume was decreased. Because of the small change in LVESV, the ejection fraction (EF) of the left ventricle significantly decreased from 0.61 +/- 0.1 preoperatively to 0.48 +/- 0.1 postoperatively. The cardiac index (CI) remained in the range of 1.9-2.5 l/min/m2 with a mean of 2.2 +/- 0.2 l/min/m2 at 1 month after operation. But, later, improvement in EF was observed in one case, in which the CI increased from 2.5 to 3.2 l/min/m2.(ABSTRACT TRUNCATED AT 250 WORDS)
Six handicapped and six nonhandicapped subjects were given exercise tolerance tests on land and in a water environment. The subjects exercised with their arms only and had their cardiopulmonary performance evaluated. Based upon the results observed in this study, it appears that nonambulatory individuals with low fitness levels were able to experience greater cardiopulmonary work outputs when exercising in a water environment. The less severely handicapped individuals displayed similar patterns to those observed in the NH subjects (i.e., no observable pattern) and thus, may not receive as great a benefit as the more severely handicapped. The water environment appears to improve venous return, cardiac output and lung ventilation, which assists the H subjects to be more efficient during exercise.
Persistent fever during active-phase IE is an indication for surgical treatment in the light of the causative organism and the underlying disease. To counter worsening hemodynamics, surgery may be the only feasible way. Surgery is performed when the patient does not respond to vasodilators and he shows an FS of less than 25%. The introduction of translocation provides a solution for the treatment of active IE. Lesions, vegetations more than 5 mm in diameter, periannular abscess, and mycotic aneurysm that could never be overlooked by two-dimensional echocardiography may hasten the early-stage decision of ways to treat IE.
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