[Letter: Side effects of perhexiline maleate. Identification of a population with an increased risk of intolerance].
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Biomedical subjects
Publications and source records attributed to A Grand.
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The observations of 2 patients having carotid sinus syncopes treated by temporary (1 case), or definitive (1 case) endovenous demand cardiac pacing are correlated with 15 similar observations found in the literature. In all these patients, cardiac pacing is more effective than all the other treatments cutting off the hyperactive reflex. Indeed, carotid sinus hypersensibility seems to be good, though unusual indication of cardiac pacing.
A new case report of acute pericarditis due to Rickettsia conori, the seventh to be published in the French literature, highlights the following facts:--the widespread distribution of fièvre boutonneuse, which is to be found in a wide strip around the Meditteranean basin;--the mechanism by which the pericardium is affected, which is probably auto-immune;--the criteria for the biological diagnosis of the Rickettsial diseases;--above all, the neccessity for prolonged antibiotic therapy, however apparently benign the disease may have seemed.
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