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Biomedical subjects

A G Cox

Publications and source records attributed to A G Cox.

At least 55 records · Page 3Linked to original sources
PubMed1970

Supersensitivity and gastric emptying after vagotomy.

Investigations were carried out in man and dog to study the validity of Cannon's law of denervation supersensitivity in relation to parasympathetic denervation of the stomach. Subthreshold doses of carbachol did not accelerate gastric emptying before vagotomy but caused a significant increase in the rate of gastric emptying after vagotomy. These findings may be relevant to aberrations of gastrointestinal motility after vagotomy and may provide the basis of a test for completeness of gastric vagotomy.

Animals↗
PubMed1969

Significance of early and late positive responses to insulin hypoglycaemia in patients with intact vagi.

Insulin tests were performed on 100 subjects with duodenal ulcer who had not undergone surgery. Thirty-seven per cent had ;late' positive responses to insulin. It was suggested that a late response to insulin after surgery was not necessarily an indication of ;adequate' vagotomy. The secretory responses to insulin before operation revealed no difference in peak acid concentrations or outputs between those with early and late responses. Basal acid concentrations were higher in those with late responses, though the difference was only significant when the division between early and late responses was made at 60 minutes. The distribution of the timing of the peak responses suggested that the division into ;early' and ;late' responders was artificial.

Duodenal Ulcer↗