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Biomedical subjects

A Franco

Publications and source records attributed to A Franco.

At least 307 records · Page 17Linked to original sources

[Objective evaluation of arterial intermittent claudication by the walking tolerance test. Comparative study of physiological walking and walking on a conveyor belt (author's transl)].

Two methods are used to evaluate the walking distance: physiological walking along a standard path (0% - 6 mk/h) and walking on a tread mill (10% - 3 km/h). In both tests, four data are checked: -- initial trouble distance, -- cramp or walking-distance, -- localisation of pain, -- recovery time. These tests are dependable for the diagnosis of arterial claudication, reproducible and well tolerated. Their results have been compared: there is no correlation between the initial trouble distance and the cramp distance. However there is a correlation between the cramp distance by physiological walking and on treadmill. Recovery time, if long, is a criteria of gravity. Interests of both methods are discussed.

Adult↗

[Results of the physiotherapy of arterial disease at the stage of intermittent claudication by programmed efforts training (author's transl)].

The results of treatment of intermittent claudication by a physical training programmed during 30 to 45 days in a rehabilitation center, are assessed on 148 patients of whom 105 have followed a full program at first (32 cases) or after surgery (73 cases). Ankle pressures are not altered. Irrigraphy shows a significant increase of 10 to 14% of the proximal indexes. Walking distance is greatly increased. 13 patients had a walking distance of about 900 m at the beginning and 31 patients at the end of the course ("functional remission"). Out of 105 patients, 98 showed improvement, 4 remained unchanged and 3 slightly worsened. The appreciation of his own progress is a strong psychological stimulation for the patient, this helping him to accent his illness, and to fight the corrigible risk factors of atherosclerosis, all significantly reduced. The interpretation of the results is discussed and shows the importance of non-hemodynamic factors in the achieved progress. The programmed exercise training is one of the best non surgical symptomatic treatments of intermittent claudication.

Adult↗

Effect of a Salmonella group H1 R factor on virulence and response of infections to antimicrobial therapy.

A group H1 R factor encoding resistance to chloramphenicol, streptomycin, sulfonamide, and tetracycline was transferred into Salmonella typhimurium LT-2. The virulence of LT-2 for mice, as assessed by intraperitoneal 50% lethal dose and the number of organisms in the spleen, was not affected by the R factor. On the other hand, the R factor conferred resistance in mouse infections to therapy with chloramphenicol and trimethoprim plus sulfamethoxazole.

Animals↗

[Partial blockage of the inferior vena cava. Results apropos of 110 cases].

Rheoplethysmography with occlusion (RPO) is useful in the diagnosis of deep venous thrombosis. Bilateral phlebography with cavography performed afterwards as an emergency gives information as to the embolic potential of the thrombosis and orientates treatment towards surgical interruption of the inferior vena cava. In the C.H.U. at Grenoble 83 clips, 25 umbrella filters and 2 ligatures were placed on the inferior vena cava from 1974 to 1977. Prevention of pulmonary emboli was achieved in 99% cases with lower limb embolic foci. Follow-up by RPO and isotopic phlebography showed that the course of venous thrombosis of the lower limbs seemed to be unchanged by partial interruption of the inferior vena cava, provided that elastic stockings and adequate anticoagulant therapy adapted to venous haemodynamics are used.

Adult↗

[Mortality by burns in children (author's transl)].

The mortality rate among 1,490 children, aged zero to fourteen years, hospitalized in the Burns Unit of Departament of Plastic Surgery in Ciudad Sanitaria de la Seguridad Social de Sevilla is studied. Analysis determined death probabilities for each case according to percentage of burned surface and age, and also LD50 in different age groups. The mortality analysis showed lethal factors related with primary care and evacuation, responsible for a decrease in survival probabilities of the children. Children with severe burns must be hospitalized in special units, which must have a high level of training in hydroelectrolitics disturbances and surgical management of this type of patients, who require homo or xenografts frequently.

Adolescent↗

[Myxoma of the left ventricle. Apropos of a successfully operated case].

Left ventricular myxomata are exceptional (12 published cases). In the case reported, the clinical picture included emboli (cerebral and coronary) and syncope. Auscultation, the electrocardiogram and the phonomechanocardiographic tracings suggested an impaired left ventricular ejection, while the left ventriculography demonstrated the tumour and the coronary arteriography its vascular relationship with the right coronary artery. Cure was obtained by surgical removal. In that respect, an attempt was made to describe the clinical and paraclinical bases for the diagnosis of the myxomata of the left ventricle.

Child↗