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Biomedical subjects

A Flatmark

Publications and source records attributed to A Flatmark.

At least 217 records · Page 12Linked to original sources
PubMed1975

Early colectomy in severe ulcerative colitis.

Before 1 February 1967 patients with severe attacks of ulcerative colitis were usually operated on after a prolonged period of medical treatment, and the mortality was 22%. During a 7-year period, beginning 1 February 1967, early colectomy has been perfomed in 21 patients with toxic megacolon and 58 patients with fulminating colitis. Immediate mortality in these 79 patients was 1.2% (one death). Two more patients died in connection with secondary operations. Thus the overall operative mortality in the present series was 3.7%.

Adolescent↗
PubMed1975

Ileorectal anastomosis in ulcerative colitis. Results in 57 patients.

The early results of colectomy and ileorectal anastomosis (IRA) in 57 patients with ulcerative colitis seemed fair. The operative mortality was relatively low (7%) also in fulminating cases (10.5%), which constituted one-third of the material. The late results were less satisfactory. Half the survivors were in need of rectal extirpation and ileostomy because of rectal dysfunction. Until now 6% have developed cancer of the rectal stump. The early diagnosis of this condition was difficult. The results regarding rectal function, stenosis, and inflammation were significantly worse in women than in men. Moreover, dyspareunia was a severe problem in more than half the women. We have abandoned IRA in the treatment of ulcerative colitis.

Adolescent↗
PubMed1975

Complete biliocolic fistula.

A case of postoperative complete biliocolic fistula is described. The patient had 10 daily voluminous motions of diarrhoea and lost 14 kg in weight in the course of two months. Increased faecal fat excretion was demonstrated. Treatment with oral tetracyclines resulted in cessation of the watery diarrhoea and some weight gain, but steatorrhoea persisted. Closure of the biliocolic fistula with re-established bile flow to the proximal small intestine cured the patient. A discussion of the case based on the present knowledge of bile salt metabolism and bile salt- bacterial interrelationship is presented.

Adult↗